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DudeMeds vs Sesame

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

DudeMeds vs Sesame: Overview

Choosing between DudeMeds and Sesame for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

DudeMeds focuses on semaglutide at $149/month with a rating of 7.6/10. Sesame also provides both semaglutide and tirzepatide at $89/month with a 7.9/10 rating.

The price difference of $60/month is significant - Sesame is the more budget-friendly option, while DudeMeds positions itself as a premium service.

Our recommended brand

After reviewing all 86 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$60/mo

Rating Difference

0.3

Winner

Sesame

Best For

Budget

DudeMeds

View full DudeMeds review →

Rating

7.6/10

Monthly Price

$149

Medications

semaglutide

Pros

✓The subscription terms are handled better than most in this category: renewals are disclosed up front and an email is sent before each renewal 'confirming the amount, date, and upcoming charge'
✓You can cancel or pause at any time from your account or by emailing care@dudemeds.com, and a support address is published rather than hidden behind a form
✓No membership fee, no separate doctor fee and free shipping, with medication typically shipped within 48 hours of approval
✓Oral and injectable GLP-1 options, with prices advertised from $149 a month
✓Plan lengths run from monthly to 12 months, so a short commitment is possible
✓24/7 patient portal with clinician messaging for dose adjustments
✓Explicitly accepts transfers from other GLP-1 and TRT clinics, which is useful if you are already mid-treatment elsewhere
✓Failed payments are retried a stated maximum of three times over 30 days rather than indefinitely

Cons

✗Published product information is thin. There is no dedicated GLP-1 product page, no named medication and dose list, and no price ladder - just 'Prices from: $149+ / month'
✗We could not find a compounded-medication disclosure anywhere on the site. Every comparable provider states in writing that compounded drugs are not FDA-approved; DudeMeds does not appear to
✗Semaglutide appears only in customer testimonials, not in any product description we could locate, so what you are actually buying is unclear until you are in the funnel
✗Trustpilot sits at 2.5 out of 5, though from just 8 reviews
✗Once a prescription is filled and shipped, that portion is non-refundable
✗The site's legal documents are buried behind a 'Legal' index page rather than linked directly, and the refund terms sit inside 'Terms of Sale' rather than a named refund policy
✗GLP-1 treatment sits alongside ED, TRT, hair loss and herpes products in a men's-lifestyle brand, so the weight-loss programme gets little dedicated clinical content
✗The marketing voice is aggressively gendered - 'We aren't in the business of making safe spaces' - which tells you who the service is designed for

Choose DudeMeds

Sesame

View full Sesame review →

Rating

7.9/10Better

Monthly Price

$89Cheaper

Medications

semaglutidetirzepatide

Pros

✓Very affordable
✓Transparent pricing
✓No subscription required
✓Multiple providers

Cons

✗Pay per visit
✗No dedicated support
✗Less hand-holding

Feature-by-feature comparison

Feature	DudeMeds	Sesame
Monthly Price	$149	$89
Rating	7.6/10	7.9/10
Medications	semaglutide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	24/7 patient portal claimed	Mon-Fri 9AM-6PM ET
Live Chat	No	Available
Free Shipping	Yes	No
Shipping Speed	Typically ships within 48 hours of approval	3-5 days
Mobile App	No	Available
Dedicated Coach	Not included	Not included
Follow-up Frequency	24/7 portal messaging with clinicians	As needed
Money-back Guarantee	None published; once a prescription is filled and shipped it is non-refundable	None
Cancellation Policy	Cancel or pause any time from your account or by email before your renewal date, with an email notice sent before each renewal	No subscription

Which should you choose?

Choose DudeMeds if you:

→Value: the subscription terms are handled better than most in this category: renewals are disclosed up front and an email is sent before each renewal 'confirming the amount, date, and upcoming charge'

Get started with DudeMeds

Choose Sesame if you:

→Want to save $60/month with a more affordable option
→Prefer a higher-rated service (7.9/10 vs 7.6/10)
→Want more medication options to choose from
→Value: very affordable

Get started with Sesame

Website previews

DudeMeds

DudeMeds website

Sesame

Sesame website

Our recommendation

Sesame comes out ahead with a higher rating of 7.9/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Sesame

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