Sesame vs Zepbound
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Sesame vs Zepbound: Overview
Choosing between Sesame and Zepbound for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Sesame offers both semaglutide and tirzepatide at $89/month with a rating of 7.9/10. Zepbound offers tirzepatide at $450/month with a 9.3/10 rating.
The price difference of $361/month is significant - Sesame is the more budget-friendly option, while Zepbound positions itself as a premium service.
Our recommended brand
After reviewing all 77 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Sesame
View full Sesame review →Pros
- ✓Very affordable
- ✓Transparent pricing
- ✓No subscription required
- ✓Multiple providers
Cons
- ✗Pay per visit
- ✗No dedicated support
- ✗Less hand-holding
Zepbound
View full Zepbound review →Pros
- ✓FDA-approved for chronic weight management
- ✓Weekly injection
- ✓Superior weight loss results (~21% average)
- ✓Same active ingredient as Mounjaro
- ✓Dual GIP/GLP-1 receptor agonist
Cons
- ✗Requires prescription and medical supervision
- ✗Can cause GI side effects
- ✗High cost without insurance coverage
- ✗Not available in all pharmacies
Feature-by-feature comparison
| Feature | Sesame | Zepbound |
|---|---|---|
| Monthly Price | $89 | $450 |
| Rating | 7.9/10 | 9.3/10 |
| Medications | semaglutide, tirzepatide | tirzepatide |
| Insurance Accepted | No | Yes |
| Support Hours | Mon-Fri 9AM-6PM ET | Mon-Fri 8AM-8PM ET |
| Live Chat | Available | No |
| Free Shipping | No | No |
| Shipping Speed | 3-5 days | Varies by pharmacy |
| Mobile App | Available | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | As needed | As prescribed by physician |
| Money-back Guarantee | None | Savings card available for eligible patients |
| Cancellation Policy | No subscription | Prescription-based, consult doctor |
Which should you choose?
Choose Sesame if you:
- →Want to save $361/month with a more affordable option
- →Want more medication options to choose from
- →Value: very affordable
Choose Zepbound if you:
- →Prefer a higher-rated service (9.3/10 vs 7.9/10)
- →Need insurance coverage for your treatment
- →Value: fda-approved for chronic weight management
Website previews
Sesame
Zepbound
