Zepbound vs Sesame

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Zepbound vs Sesame: Overview

Choosing between Zepbound and Sesame for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Zepbound focuses on tirzepatide at $450/month with a rating of 9.3/10. Sesame also provides both semaglutide and tirzepatide at $89/month with a 7.9/10 rating.

The price difference of $361/month is significant - Sesame is the more budget-friendly option, while Zepbound positions itself as a premium service.

VERIFIED

Our recommended brand

After reviewing all 78 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

At a glance

Price Difference
$361/mo
Rating Difference
1.4
Winner
Zepbound
Best For
Quality

Zepbound

View full Zepbound review →
Rating
9.3/10Better
Monthly Price
$450
Medications
tirzepatide

Pros

  • FDA-approved for chronic weight management
  • Weekly injection
  • Superior weight loss results (~21% average)
  • Same active ingredient as Mounjaro
  • Dual GIP/GLP-1 receptor agonist

Cons

  • Requires prescription and medical supervision
  • Can cause GI side effects
  • High cost without insurance coverage
  • Not available in all pharmacies
Choose Zepbound

Sesame

View full Sesame review →
Rating
7.9/10
Monthly Price
$89Cheaper
Medications
semaglutidetirzepatide

Pros

  • Very affordable
  • Transparent pricing
  • No subscription required
  • Multiple providers

Cons

  • Pay per visit
  • No dedicated support
  • Less hand-holding
Choose Sesame

Feature-by-feature comparison

FeatureZepboundSesame
Monthly Price$450$89
Rating9.3/107.9/10
Medicationstirzepatidesemaglutide, tirzepatide
Insurance AcceptedYesNo
Support HoursMon-Fri 8AM-8PM ETMon-Fri 9AM-6PM ET
Live ChatNoAvailable
Free ShippingNoNo
Shipping SpeedVaries by pharmacy3-5 days
Mobile AppNoAvailable
Dedicated CoachNot includedNot included
Follow-up FrequencyAs prescribed by physicianAs needed
Money-back GuaranteeSavings card available for eligible patientsNone
Cancellation PolicyPrescription-based, consult doctorNo subscription

Which should you choose?

Choose Zepbound if you:

  • Prefer a higher-rated service (9.3/10 vs 7.9/10)
  • Need insurance coverage for your treatment
  • Value: fda-approved for chronic weight management

Choose Sesame if you:

  • Want to save $361/month with a more affordable option
  • Want more medication options to choose from
  • Value: very affordable

Website previews

Zepbound

Zepbound website

Sesame

Sesame website

Our recommendation

Zepbound comes out ahead with a higher rating of 9.3/10.
Get started with Zepbound

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