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Sesame vs Yucca Health

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Sesame vs Yucca Health: Overview

Choosing between Sesame and Yucca Health for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Sesame offers both semaglutide and tirzepatide at $89/month with a rating of 7.9/10. Yucca Health also provides both semaglutide and tirzepatide at $146/month with a 8/10 rating.

The price difference of $57/month is significant - Sesame is the more budget-friendly option, while Yucca Health positions itself as a premium service.

Our recommended brand

After reviewing all 92 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$57/mo

Rating Difference

0.1

Winner

Yucca Health

Best For

Quality

Sesame

View full Sesame review →

Rating

7.9/10

Monthly Price

$89Cheaper

Medications

semaglutidetirzepatide

Pros

✓Very affordable
✓Transparent pricing
✓No subscription required
✓Multiple providers

Cons

✗Pay per visit
✗No dedicated support
✗Less hand-holding

Yucca Health

View full Yucca Health review →

Rating

8/10Better

Monthly Price

$146

Medications

semaglutidetirzepatide

Pros

✓The FAQ publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked July 27, 2026
✓A lifetime price lock is offered under code YUCCA4LIFE at $146/mo, which if honoured protects against the mid-treatment increases common in this category
✓Trustpilot rating of 4.6 across 1,197 reviews, closely matching the figure shown on site
✓The compounded, not-FDA-approved status is spelled out in full, including the point that these drugs do not undergo FDA review for manufacturing quality
✓The whole site is available in Spanish, which almost no other provider in this category offers
✓Licensed providers in all 50 states, US-licensed pharmacies and free expedited shipping
✓Refund policy and shipping policy are both published as separate documents
✓NAD+ and sermorelin are available if you want more than weight care, without being bundled into the GLP-1 price

Cons

✗A developer's note is rendering inside the live page. Between the product cards the text reads: 'the SSR pass triggers an "Invalid hook call" because the React renderer dispatcher is null in the Cloudflare Workers SSR pipeline'. An engineering comment left in production is not reassuring on a site handling prescriptions
✗Secondary product pricing contradicts itself: NAD+ is shown as 'Starting at $158' in one block and 'As low as $215' in another, and sermorelin as both '$158' and '$199'
✗'Pricing is shared after intake once eligibility is confirmed' sits directly above a FAQ answer that then states all the prices, so the site cannot decide whether pricing is gated
✗Social-proof counters disagree with each other - one product card claims '1000+ Patients enrolled in last 7 days' while others on the same page say '100+'
✗Describing compounded products as having 'the same active pharmaceutical ingredients as brand-name drugs' is the claim type the FDA cited in a February 2026 warning letter to a competitor, even though Yucca does disclaim FDA approval immediately afterwards
✗The 'for life' price lock has no published terms explaining what would void it
✗No published phone number or support hours
✗No BBB profile or complaint record to check against the Trustpilot score

Choose Yucca Health

Feature-by-feature comparison

Feature	Sesame	Yucca Health
Monthly Price	$89	$146
Rating	7.9/10	8/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Mon-Fri 9AM-6PM ET	Not published
Live Chat	Available	No
Free Shipping	No	Yes
Shipping Speed	3-5 days	Free expedited shipping claimed
Mobile App	Available	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	As needed	Not published
Money-back Guarantee	None	A refund policy is published as a separate document; no blanket money-back guarantee is advertised
Cancellation Policy	No subscription	Published separately; the lifetime price lock has no stated conditions

Which should you choose?

Choose Sesame if you:

→Want to save $57/month with a more affordable option
→Value: very affordable

Get started with Sesame

Choose Yucca Health if you:

→Prefer a higher-rated service (8/10 vs 7.9/10)
→Value: the faq publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked july 27, 2026

Get started with Yucca Health

Website previews

Sesame

Sesame website

Yucca Health

Yucca Health website

Our recommendation

Yucca Health comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Yucca Health

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