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AgelessRx vs PlushCare

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

AgelessRx vs PlushCare: Overview

Choosing between AgelessRx and PlushCare for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

AgelessRx offers both semaglutide and tirzepatide at $99/month with a rating of 8.4/10. PlushCare also provides both semaglutide and tirzepatide at $20/month with a 8.5/10 rating.

The price difference of $79/month is significant - PlushCare is the more budget-friendly option, while AgelessRx positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$79/mo

Rating Difference

0.1

Winner

PlushCare

Best For

Budget

AgelessRx

View full AgelessRx review →

Rating

8.4/10

Monthly Price

$99

Medications

semaglutidetirzepatideliraglutidemetformin

Pros

✓The branded-drug pricing model is the most cost-honest we have seen: $50 + cost of medication for the Wegovy pill, and $65 + medication for Wegovy or Zepbound, with the drug supplied through the manufacturer's own direct programme rather than marked up
✓Compounded microdosing options are cheap by category standards: microdosing semaglutide from $99/month and microdosing tirzepatide from $159/month (checked July 27, 2026)
✓Metformin from $25/month for patients who do not need or want a GLP-1
✓Eligibility is framed clinically rather than universally - 'Ideal for adults with BMI >27' and 'Use with reduced-calorie meal plan and exercise for best results'
✓Efficacy figures are attached to the FDA-approved products they actually come from, such as the 14% average for the Wegovy pill, rather than being borrowed for compounded versions
✓Trustpilot rating of 4.4 across 2,407 reviews
✓Longevity-trained clinicians and a broader diagnostic offering including BioAge tests and health monitoring
✓Compounded liraglutide is offered with a specific safety warning about allergic reactions, rather than generic boilerplate

Cons

✗The core compounded offering is microdosing, which is not an evidence-based protocol. The trials behind semaglutide and tirzepatide used full therapeutic doses; there is no comparable evidence for the lower doses sold here, and AgelessRx's own wording only claims it 'may support moderate weight loss'
✗If you want the weight loss the headline GLP-1 figures describe, microdosing is unlikely to deliver it - this is positioned as longevity support, not maximal weight reduction
✗A fourth price appears at category level: the GLP-1 landing block says 'Starting at $139' while the individual products are listed at $99 and $159. That $139 matches nothing on the page
✗For the branded route you pay the monitoring fee plus the full manufacturer price, so the real monthly cost is far above the $50-65 shown and depends entirely on the drug
✗The compounded disclosure is brief - it notes the products come from a licensed compounding pharmacy but does not state plainly on the product page that they are not FDA-approved
✗No published refund or cancellation policy was found on the pages we checked
✗No customer phone number or support hours are published
✗GLP-1 sits inside a wide longevity catalogue, so the weight-management pathway competes for attention with NAD+, GSH and BioAge testing

Choose AgelessRx

PlushCare

View full PlushCare review →

Rating

8.5/10Better

Monthly Price

$20Cheaper

Medications

semaglutidetirzepatideliraglutide

Pros

✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
✓Membership is $19.99/month with the first month free, and there is no minimum commitment
✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
✓A full refund is offered if the doctor is unable to treat you
✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure

Cons

✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site

Choose PlushCare

Feature-by-feature comparison

Feature	AgelessRx	PlushCare
Monthly Price	$99	$20
Rating	8.4/10	8.5/10
Medications	semaglutide, tirzepatide, liraglutide, metformin	semaglutide, tirzepatide, liraglutide
Insurance Accepted	No	Yes
Support Hours	Not published	Video visits available 24/7
Live Chat	No	No
Free Shipping	Yes	No
Shipping Speed	Not published	Filled at your pharmacy; not shipped by PlushCare
Mobile App	No	Available
Dedicated Coach	Not included	Not included
Follow-up Frequency	Clinician monitoring included in the Access & Monitoring fee	Ongoing management with a board-certified primary care physician
Money-back Guarantee	None published	Full refund if the doctor is unable to treat you; medication and lab costs are never included
Cancellation Policy	Not published on the product pages	Cancel anytime, no minimum commitment; first month of membership is free

Which should you choose?

Choose AgelessRx if you:

→Want more medication options to choose from
→Value: the branded-drug pricing model is the most cost-honest we have seen: $50 + cost of medication for the wegovy pill, and $65 + medication for wegovy or zepbound, with the drug supplied through the manufacturer's own direct programme rather than marked up

Get started with AgelessRx

Choose PlushCare if you:

→Want to save $79/month with a more affordable option
→Prefer a higher-rated service (8.5/10 vs 8.4/10)
→Need insurance coverage for your treatment
→Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit

Get started with PlushCare

Website previews

AgelessRx

AgelessRx website

PlushCare

PlushCare website

Our recommendation

PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with PlushCare

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