Every provider below prescribes a GLP-1 medication for weight loss and publishes enough about how it works that a patient can make an informed decision before handing over a card number. They are ranked on our overall score, which weighs price transparency, whether the medication is FDA-approved or compounded, how much clinician involvement there really is, and how clearly the refund, cancellation and pharmacy arrangements are disclosed.
We score each provider on what its own website publishes, not on what its marketing claims. Points are earned for a price you can see before signing up, FDA-approved medication, named pharmacies, published contact details, and refund and cancellation terms you can read in advance. Points are lost for prices that only appear inside an intake funnel, advertised review scores that do not match the public profile, auto-escalating charges, and disclaimers that contradict the headline. Providers with a documented FDA warning letter about false or misleading claims are excluded from these rankings entirely - their reviews remain, carrying the letter in full, but a page that reads as a recommendation is the wrong place for them.
Best point: Comprehensive care
Watch out for: Higher pricing
Membership fee: None. CoreAge states "No membership fees ever" and that your refill price never changes.
Best point: FDA-approved for chronic weight management
Watch out for: Requires prescription and medical supervision
Best point: First FDA-approved oral GLP-1 for weight loss
Watch out for: Newly approved - limited real-world data
The newest FDA-approved option and the only GLP-1 pill that can be taken at any time of day with no food or water restrictions. Less weight loss than the injectables, but published trial data and published pricing.
Best point: The first and only FDA-approved GLP-1 pill for weight loss that can be taken at any time of day with no food or water restrictions, approved 1 April 2026
Watch out for: Weight loss is meaningfully lower than the best injectables. 12.4% at the top dose sits below tirzepatide territory, so if maximum weight loss is the goal an injection still wins
Membership fee: None - there is no membership, this is a prescription medicine bought per fill
Best point: FDA-approved for type 2 diabetes
Watch out for: Primarily approved for diabetes, not weight loss
Best point: FDA-approved for chronic weight management
Watch out for: Requires prescription and monitoring
Brand-name semaglutide direct from the manufacturer at a self-pay price that undercuts a good number of compounded programmes. A pharmacy, not a care programme.
Best point: Brand-name Wegovy and Ozempic bought direct from the manufacturer's own pharmacy, so there is no question about what is in the vial or the bottle
Watch out for: The $149 pill price is tied to specific doses: patients pay $149 for each month of 1.5 mg and 4 mg, and the 4 mg offer runs only until 31 August 2026, after which 4 mg is $199 per month
Membership fee: None
Best point: FDA-approved for type 2 diabetes
Watch out for: Approved for diabetes, not weight loss
Best point: In-network with most major private insurance plans and Medicare, so Care Team visits, lab tests and medication are billed through insurance and you pay only your copay or deductible. Almost no other provider on this site accepts insurance at all
Watch out for: On the $299/month self-pay plan the fee covers the care team and platform only - medication cost is separate and on top, so the true monthly outlay can be far higher than $299
What that price buys: Average out-of-pocket cost per appointment for patients with accepted insurance. Medication is billed separately by your pharmacy.
The best option if you have commercial insurance: FDA-approved medication inside a real primary-care practice, with a published average out-of-pocket cost per visit.
Best point: It bills your insurance instead of asking you to forget insurance exists. Circle Medical states it is in-network with most commercial plans
Watch out for: Your cost is whatever your plan says it is. $35 is an average, not a price - deductibles and exclusions can leave you paying far more
Membership fee: None. The site states there are no memberships or hidden fees.
What that price buys: The $59 is the recurring "Success by Sesame" programme fee, and it depends on a 12-month commitment whose annual fee is explicitly non-refundable once paid. Medication is not included: Sesame publishes those prices separately and dose by dose, so the real monthly outlay is the subscription plus the drug.
Best point: Publishes cash prices dose by dose, which no other provider on this site does. Zepbound KwikPen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
Watch out for: The $59/mo headline depends on a 12-month 'Success by Sesame' commitment, and the annual fee is explicitly non-refundable once paid - cancel in month two and you do not get the remaining ten months back
Best point: $179/month is genuinely all-in. Henry states the price 'includes the cost of your provider visits, medication, supplies, and ongoing support' - there is no separate membership fee stacked on top, which is the trap several competitors rely on
Watch out for: Cancelling early can cost you. The terms note you 'may be required to pay out the rest of your balance unless you're unable to continue for medical-related reasons as determined by a healthcare provider', so a plan is not simply walk-away
Membership fee: None separate. Henry describes one monthly payment covering the provider visit, medication, supplies and ongoing care.
Best point: Advanced technology
Watch out for: Higher pricing
Best point: Prescribes FDA-approved, brand-name GLP-1s - Zepbound, Wegovy pen and pill, Ozempic, Saxenda and the new Foundayo pill - rather than compounded copies
Watch out for: The membership fee does not include your medication. At $149/mo month-to-month plus $449/mo for a maintenance dose of Zepbound, the realistic all-in cost is roughly $520-600 a month
Membership fee: The Ro Body membership is $39 for the first month, then $74-$149/month depending on the plan you choose - $74/month requires an annual prepaid plan. The $39 is refunded if you are not eligible for GLP-1s.
Best point: Psychology-based approach
Watch out for: Requires Noom subscription
Three things separate the good from the rest: whether the medication is FDA-approved or compounded, whether the full price is published before you sign up, and how much real clinician involvement there is. A provider that hides pricing until you have completed an intake, or that raises your bill every time your dose goes up, is optimising for conversion rather than for you.
No. Price mostly reflects the medication type and the business model, not the quality of care. Brand-name Wegovy bought direct from NovoCare Pharmacy costs less per month than several compounded programmes, and some of the cheapest compounded plans come with the tightest lock-ins.
A minority do. Most online GLP-1 services are cash-pay because insurers frequently deny weight-loss medication. Providers that bill insurance and handle prior authorisation for you are usually the cheapest route if your plan covers a GLP-1 at all - and the most frustrating if it does not.
Best semaglutide providers
Best tirzepatide providers
Best compounded GLP-1 providers
Cheapest GLP-1 programs
What the trials actually showed, how the two drugs differ, and which one suits which patient.
What compounded actually means, why the price gap has narrowed, and the questions to ask first.
Every pricing model in the market, decoded - and why the advertised number is rarely the real one.
The BMI thresholds, the contraindications that rule people out, and what providers actually check.
The common ones, the serious ones, and the practical steps that reduce the day-to-day misery.
Cold chain, room-temperature windows, what to do when a package sits in the sun, and why it matters.
This page is editorial research, not medical advice. GLP-1 medications are prescription drugs with real risks and contraindications, and a ranking cannot tell you whether one is right for you. Only a licensed clinician who knows your history can do that. Prices and policies in this market change frequently - confirm the current terms with any provider before you buy.