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AgelessRx vs Shameless Care

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

AgelessRx vs Shameless Care: Overview

Choosing between AgelessRx and Shameless Care for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

AgelessRx offers both semaglutide and tirzepatide at $99/month with a rating of 8.4/10. Shameless Care also provides both semaglutide and tirzepatide at $109/month with a 8/10 rating.

With only a $10/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$10/mo

Rating Difference

0.4

Winner

AgelessRx

Best For

Budget

AgelessRx

View full AgelessRx review →

Rating

8.4/10Better

Monthly Price

$99Cheaper

Medications

semaglutidetirzepatideliraglutidemetformin

Pros

✓The branded-drug pricing model is the most cost-honest we have seen: $50 + cost of medication for the Wegovy pill, and $65 + medication for Wegovy or Zepbound, with the drug supplied through the manufacturer's own direct programme rather than marked up
✓Compounded microdosing options are cheap by category standards: microdosing semaglutide from $99/month and microdosing tirzepatide from $159/month (checked July 27, 2026)
✓Metformin from $25/month for patients who do not need or want a GLP-1
✓Eligibility is framed clinically rather than universally - 'Ideal for adults with BMI >27' and 'Use with reduced-calorie meal plan and exercise for best results'
✓Efficacy figures are attached to the FDA-approved products they actually come from, such as the 14% average for the Wegovy pill, rather than being borrowed for compounded versions
✓Trustpilot rating of 4.4 across 2,407 reviews
✓Longevity-trained clinicians and a broader diagnostic offering including BioAge tests and health monitoring
✓Compounded liraglutide is offered with a specific safety warning about allergic reactions, rather than generic boilerplate

Cons

✗The core compounded offering is microdosing, which is not an evidence-based protocol. The trials behind semaglutide and tirzepatide used full therapeutic doses; there is no comparable evidence for the lower doses sold here, and AgelessRx's own wording only claims it 'may support moderate weight loss'
✗If you want the weight loss the headline GLP-1 figures describe, microdosing is unlikely to deliver it - this is positioned as longevity support, not maximal weight reduction
✗A fourth price appears at category level: the GLP-1 landing block says 'Starting at $139' while the individual products are listed at $99 and $159. That $139 matches nothing on the page
✗For the branded route you pay the monitoring fee plus the full manufacturer price, so the real monthly cost is far above the $50-65 shown and depends entirely on the drug
✗The compounded disclosure is brief - it notes the products come from a licensed compounding pharmacy but does not state plainly on the product page that they are not FDA-approved
✗No published refund or cancellation policy was found on the pages we checked
✗No customer phone number or support hours are published
✗GLP-1 sits inside a wide longevity catalogue, so the weight-management pathway competes for attention with NAD+, GSH and BioAge testing

Choose AgelessRx

Shameless Care

View full Shameless Care review →

Rating

8/10

Monthly Price

$109

Medications

sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline

Pros

✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost

Cons

✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
✗Not available in all 50 states - the site states 49
✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron

Choose Shameless Care

Feature-by-feature comparison

Feature	AgelessRx	Shameless Care
Monthly Price	$99	$109
Rating	8.4/10	8/10
Medications	semaglutide, tirzepatide, liraglutide, metformin	sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Not published	Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Clinician monitoring included in the Access & Monitoring fee	Board-certified physician assigned from start to finish; ongoing cadence not published
Money-back Guarantee	None published	Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published
Cancellation Policy	Not published on the product pages	No subscriptions - every purchase is one-off, so there is nothing to cancel

Which should you choose?

Choose AgelessRx if you:

→Want to save $10/month with a more affordable option
→Prefer a higher-rated service (8.4/10 vs 8/10)
→Value: the branded-drug pricing model is the most cost-honest we have seen: $50 + cost of medication for the wegovy pill, and $65 + medication for wegovy or zepbound, with the drug supplied through the manufacturer's own direct programme rather than marked up

Get started with AgelessRx

Choose Shameless Care if you:

→Want more medication options to choose from
→Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)

Get started with Shameless Care

Website previews

AgelessRx

AgelessRx website

Shameless Care

Shameless Care website

Our recommendation

AgelessRx comes out ahead with a higher rating of 8.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with AgelessRx

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