← All providers

altRx vs Direct Meds

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

altRx vs Direct Meds: Overview

Choosing between altRx and Direct Meds for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

altRx offers both semaglutide and tirzepatide at $149/month with a rating of 6.5/10. Direct Meds also provides both semaglutide and tirzepatide at $297/month with a 8/10 rating.

The price difference of $148/month is significant - altRx is the more budget-friendly option, while Direct Meds positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$148/mo

Rating Difference

1.5

Winner

Direct Meds

Best For

Quality

altRx

View full altRx review →

Rating

6.5/10

Monthly Price

$149Cheaper

Medications

semaglutidetirzepatide

Pros

✓Flat pricing across doses is promised in the banner: "SAME PRICE EVERY MONTH"
✓Promotional rates published up front - GLP-1 from $89/month and GLP-1 + GIP from $149/month
✓24/7 support advertised, and no insurance required

Cons

✗The FDA has formally told altRx that its labelling and its "clinically proven" claims misrepresented its compounded products - see the warning letter above
✗The medication is compounded and therefore not FDA-approved - the agency has not reviewed it for safety, effectiveness or manufacturing quality
✗Compounded GLP-1 pricing in this tier is cheap partly because the product carries none of the trial programme, patent or distribution costs of the approved drug - and none of its regulatory review either
✗The headline rates are a dated summer promotion ("OFFER ENDS AUGUST 5TH AT MIDNIGHT") against a standing price of $199/month, so the advertised figure is not the ongoing one
✗No phone number, refund policy or pharmacy named on the site

Direct Meds

View full Direct Meds review →

Rating

8/10Better

Monthly Price

$297

Medications

semaglutidetirzepatide

Pros

✓The compounding explanation is genuinely educational, citing USP 795 and USP 797 and identifying the pharmacy as a 503A facility rather than hand-waving about 'FDA-registered' status
✓Trustpilot rating of 4.6 from 12,750 reviews, a large and credible independent sample
✓The FAQ states flat monthly prices with no membership layered on: $297/month for semaglutide and $399/month for tirzepatide (checked July 27, 2026)
✓That price is stated to include the medication, doctor visits normally billed at $99 each, next-day FedEx or UPS shipping, and all injection supplies
✓Same price at every dose, so titrating up does not increase the bill
✓A full refund is given if your prescription is not approved
✓A published customer phone number, 888-696-7176, which most competitors do not offer
✓This offer is restricted in only one state, Arkansas

Cons

✗The headline price and the real price do not match. The landing page leads with 'Starting at $147' while the FAQ on the same site states 'For Semaglutide we charge $297/month. For Tirzepatide we charge $399/month' - roughly double
✗Discounts are advertised in three different sizes on one page: '$150 Off Today', 'Up to $200 OFF' and 'Get $150 OFF your prescription instantly', with no terms attached to any of them
✗The 'patient satisfaction guarantee' is undefined - 'If you are unhappy with your results, let us know and we'll make it right' commits to nothing specific
✗The landing page uses the same template as several other compounded GLP-1 funnels, down to the identical headline 'The proven way to lose 15% of your body weight fast!'
✗'We've been featured all over' appears with no named publications or links
✗The '15% of your body weight' figure comes from trials of the branded drugs, not from Direct Meds' compounded product or its own patients
✗No BBB profile could be found to set against the Trustpilot score
✗Support hours are not published, only the phone number and an email address

Choose Direct Meds

Feature-by-feature comparison

Feature	altRx	Direct Meds
Monthly Price	$149	$297
Rating	6.5/10	8/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	Available
Free Shipping	Yes	Yes
Shipping Speed	Not published	Next-day FedEx or UPS; arrives in 1-2 days
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Not published	1:1 medical support with messaging and refills
Money-back Guarantee	None published	Full refund if your prescription is not approved; a vaguely worded satisfaction guarantee otherwise
Cancellation Policy	Not published	Cancel anytime, no monthly membership

Which should you choose?

Choose altRx if you:

→Want to save $148/month with a more affordable option
→Value: flat pricing across doses is promised in the banner: "same price every month"

Get started with altRx

Choose Direct Meds if you:

→Prefer a higher-rated service (8/10 vs 6.5/10)
→Value: the compounding explanation is genuinely educational, citing usp 795 and usp 797 and identifying the pharmacy as a 503a facility rather than hand-waving about 'fda-registered' status

Get started with Direct Meds

Website previews

altRx

altRx website

Direct Meds

Direct Meds website

Our recommendation

Direct Meds comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Direct Meds

Related comparisons

altRx vs CoreAge Rx

altRx vs Zepbound

altRx vs Mounjaro

altRx vs Wegovy Pill

altRx vs Foundayo

altRx vs Wegovy

altRx vs NovoCare Pharmacy

altRx vs Ozempic

altRx vs Form Health

altRx vs Henry Meds

altRx vs Sesame Care

altRx vs FuturHealth

altRx vs Circle Medical

altRx vs Ro

altRx vs Midi Health

altRx vs Noom Med

altRx vs Precision Telemed

altRx vs Hims

altRx vs Calibrate

altRx vs PlushCare

Compare other providers

Compare GLP-1 Brands

First Brand

vs

Second Brand