← All providers

Amie vs RxSpan MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Amie vs RxSpan MD: Overview

Choosing between Amie and RxSpan MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Amie offers both semaglutide and tirzepatide at $99/month with a rating of 6.5/10. RxSpan MD also provides both semaglutide and tirzepatide at $249/month with a 7.6/10 rating.

The price difference of $150/month is significant - Amie is the more budget-friendly option, while RxSpan MD positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$150/mo

Rating Difference

1.1

Winner

RxSpan MD

Best For

Quality

Amie

View full Amie review →

Rating

6.5/10

Monthly Price

$99Cheaper

Medications

semaglutidetirzepatide

Pros

✓Pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
✓No shipment unless a provider approves you, stated on the pricing panel
✓Optional add-ons are priced separately and openly rather than bundled in silently

Cons

✗The FDA has formally told Amie that its website misrepresented its compounded products - see the warning letter above
✗The medication is compounded and therefore not FDA-approved - the agency has not reviewed it for safety, effectiveness or manufacturing quality
✗Compounded GLP-1 pricing in this tier is cheap partly because the product carries none of the trial programme, patent or distribution costs of the approved drug - and none of its regulatory review either
✗The three-month rate requires paying $249 up front
✗No phone number or support hours published

RxSpan MD

View full RxSpan MD review →

Rating

7.6/10Better

Monthly Price

$249

Medications

semaglutidetirzepatide

Pros

✓A full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked July 27, 2026)
✓Brand-name options are offered and priced openly too - Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069
✓The plan ladder is shown with each rate: $249/mo monthly, $219/mo on 3 months, $199/mo on 6 months and $194/mo on 12 months
✓The price is stated to include the consult, medication, supplies, shipping and support, with no separate membership fee
✓Oral capsule versions of both semaglutide and tirzepatide are available for people who do not want injections
✓Plans can be cancelled or changed at any time
✓The site states plainly that 'Prescription is not guaranteed' rather than implying approval is automatic
✓A named, credentialled physician is associated with the service rather than an anonymous 'medical team'

Cons

✗Every headline price is labelled 'For the first month'. What you pay from month two is not shown anywhere on the product screen, so the ongoing cost is unknown until you are further into the funnel
✗You pay at checkout before a provider reviews your case - the site confirms 'After checkout, a provider will review your information to determine if treatment is right for you' - so your money goes first and eligibility is decided afterwards
✗There is no independent review signal at all: no Trustpilot profile, no BBB file, and no rating displayed on site
✗Brand-name pricing is far above the manufacturers' own direct-pay programmes - $1,349 for Wegovy and $1,069 for Zepbound against considerably cheaper NovoCare and LillyDirect routes
✗No customer phone number is published; the only contact is an email address
✗The supervising physician's board certification is in plastic surgery, not obesity medicine, endocrinology or internal medicine
✗The banner copy - 'No Hidden Fees', 'Free, Expedited Delivery', 'Doctor-led Plans & Coaching' - is word-for-word identical to TrimRx's, indicating a shared white-label funnel rather than an independently built service
✗Product prices only render once JavaScript loads; with scripts blocked the weight-loss category reads 'No products found for Weight Loss'

Choose RxSpan MD

Feature-by-feature comparison

Feature	Amie	RxSpan MD
Monthly Price	$99	$249
Rating	6.5/10	7.6/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Not published; no shipment unless approved	Free expedited delivery claimed; timeframe not published
Mobile App	No	No
Dedicated Coach	Not included	Included
Follow-up Frequency	Not published	Doctor-led plans and coaching advertised; frequency not published
Money-back Guarantee	None published	None published; you are charged at checkout before a provider decides whether to prescribe
Cancellation Policy	Monthly or 3-month plans; terms not summarised on the pricing panel	Cancel or change plans at any time

Which should you choose?

Choose Amie if you:

→Want to save $150/month with a more affordable option
→Value: pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249

Get started with Amie

Choose RxSpan MD if you:

→Prefer a higher-rated service (7.6/10 vs 6.5/10)
→Want personalized coaching support included
→Value: a full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked july 27, 2026)

Get started with RxSpan MD

Website previews

Amie

Amie website

RxSpan MD

RxSpan MD website

Our recommendation

RxSpan MD comes out ahead with a higher rating of 7.6/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with RxSpan MD

Related comparisons

Amie vs CoreAge Rx

Amie vs Zepbound

Amie vs Mounjaro

Amie vs Wegovy Pill

Amie vs Foundayo

Amie vs Wegovy

Amie vs NovoCare Pharmacy

Amie vs Ozempic

Amie vs Form Health

Amie vs Henry Meds

Amie vs Sesame Care

Amie vs FuturHealth

Amie vs Circle Medical

Amie vs Ro

Amie vs Midi Health

Amie vs Noom Med

Amie vs Precision Telemed

Amie vs Hims

Amie vs Calibrate

Amie vs PlushCare

Compare other providers

Compare GLP-1 Brands

First Brand

vs

Second Brand