Calibrate vs Amie
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Calibrate vs Amie: Overview
Choosing between Calibrate and Amie for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Calibrate offers both semaglutide and tirzepatide at $199/month with a rating of 8.5/10. Amie also provides both semaglutide and tirzepatide at $99/month with a 6.5/10 rating.
The price difference of $100/month is significant - Amie is the more budget-friendly option, while Calibrate positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$100/mo
Rating Difference
2.0
Winner
Calibrate
Best For
Quality
Calibrate
View full Calibrate review →Rating
8.5/10Better
Monthly Price
$199
Medications
semaglutidetirzepatide
Pros
- ✓Prescribes only brand-name, FDA-approved GLP-1s - Zepbound, Mounjaro, Wegovy, Ozempic and Foundayo - with no compounded products
- ✓Publishes a genuine long-term outcome: 20% weight loss achieved at three years, which is a far longer follow-up than the 68-72 week trial data most providers cite
- ✓Includes 1:1 video coaching and lifestyle support rather than shipping medication and leaving you to it
- ✓Dedicated insurance navigation support to get the medication covered, instead of assuming cash-pay
- ✓Available either directly as an individual or through a participating employer
- ✓Starting price is published openly at $199/month (checked July 28, 2026)
Cons
- ✗At $199/month for the programme, this is a coaching-led service and the medication cost is separate - what you pay in total depends on your insurance
- ✗The $199 figure is a 'starting at' price
- ✗Because it only prescribes brand-name GLP-1s, cost without insurance coverage will be substantially higher than compounded alternatives
- ✗The 4.5 rating from 1,618 reviews is displayed on Calibrate's own site rather than an independent platform
- ✗GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy
Amie
View full Amie review →Rating
6.5/10
Monthly Price
$99Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓Pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
- ✓No shipment unless a provider approves you, stated on the pricing panel
- ✓Optional add-ons are priced separately and openly rather than bundled in silently
Cons
- ✗The FDA has formally told Amie that its website misrepresented its compounded products - see the warning letter above
- ✗The medication is compounded and therefore not FDA-approved - the agency has not reviewed it for safety, effectiveness or manufacturing quality
- ✗Compounded GLP-1 pricing in this tier is cheap partly because the product carries none of the trial programme, patent or distribution costs of the approved drug - and none of its regulatory review either
- ✗The three-month rate requires paying $249 up front
- ✗No phone number or support hours published
Feature-by-feature comparison
| Feature | Calibrate | Amie |
|---|---|---|
| Monthly Price | $199 | $99 |
| Rating | 8.5/10 | 6.5/10 |
| Medications | semaglutide, tirzepatide | semaglutide, tirzepatide |
| Insurance Accepted | Yes | No |
| Support Hours | Not published | Not published |
| Live Chat | No | No |
| Free Shipping | No | Yes |
| Shipping Speed | Prescriptions filled through your pharmacy | Not published; no shipment unless approved |
| Mobile App | Available | No |
| Dedicated Coach | Included | Not included |
| Follow-up Frequency | 1:1 video coaching throughout the Metabolic Reset programme | Not published |
| Money-back Guarantee | None published | None published |
| Cancellation Policy | Programme based; terms not published | Monthly or 3-month plans; terms not summarised on the pricing panel |
Which should you choose?
Choose Calibrate if you:
- →Prefer a higher-rated service (8.5/10 vs 6.5/10)
- →Need insurance coverage for your treatment
- →Want personalized coaching support included
- →Value: prescribes only brand-name, fda-approved glp-1s - zepbound, mounjaro, wegovy, ozempic and foundayo - with no compounded products
Choose Amie if you:
- →Want to save $100/month with a more affordable option
- →Value: pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
Website previews
Calibrate
Amie
Our recommendation
Calibrate comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with CalibrateRelated comparisons
Calibrate vs CoreAge Rx
$199
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vs
$99
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Calibrate vs Zepbound
$199
★ 8.5
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Calibrate vs Mounjaro
$199
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vs
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Calibrate vs Wegovy Pill
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vs
$149
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Calibrate vs Foundayo
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Calibrate vs Wegovy
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