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Call-On-Doc vs Enhance MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Call-On-Doc vs Enhance MD: Overview

Choosing between Call-On-Doc and Enhance MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Call-On-Doc offers both semaglutide and tirzepatide at $250/month with a rating of 7.9/10. Enhance MD also provides both semaglutide and tirzepatide at $212/month with a 7.7/10 rating.

With only a $38/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$38/mo

Rating Difference

0.2

Winner

Call-On-Doc

Best For

Quality

Call-On-Doc

View full Call-On-Doc review →

Rating

7.9/10Better

Monthly Price

$250

Medications

semaglutidetirzepatideliraglutide

Pros

✓A published, all-in price for the compounded semaglutide programme: $250.00 with home delivery included
✓Brand-name options are listed alongside compounded ones - Ozempic, Mounjaro, Saxenda, Wegovy, Zepbound and Contrave all appear in the medication catalogue
✓A published phone number, (214) 466-6618, plus email and text support - more contactable than most telehealth weight-loss services
✓Coverage across all 50 states plus the District of Columbia
✓Long service hours: Monday to Friday 5am to midnight CT, weekends 6am to 1am CT
✓No appointment needed - visits happen online when you start them
✓A "Subscribe & Save" programme brings general visits down to $12, useful if you use the service for more than weight loss
✓An RX Savings Card is offered to reduce prescription costs
✓Every programme includes a licensed provider visit that reviews your history and confirms the medication and dose

Cons

✗The $250 compounded semaglutide price is presented on the medication page, but the weight-loss programme pages do not carry a comparable published price for every option
✗Compounded medication is not FDA-approved and has not been reviewed by the FDA for safety, quality or efficacy
✗No refund or cancellation policy is published on the weight-loss pages
✗Insurance is not addressed on the weight-loss pages - this reads as a cash-pay service
✗Patient testimonials are duplicated verbatim across the page, which undermines their value as evidence
✗It is a broad urgent-care telehealth service first and a weight-loss provider second, so there is no dedicated coaching or nutrition programme
✗HSA/FSA acceptance is not stated

Choose Call-On-Doc

Enhance MD

View full Enhance MD review →

Rating

7.7/10

Monthly Price

$212Cheaper

Medications

semaglutidetirzepatide

Pros

✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
✓Product images are labelled 'Not actual vial - For marketing purposes only'
✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
✓Medication ships quarterly, so there are fewer delivery events to manage
✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
✗No published customer phone number or support hours
✗No BBB profile or independent complaint record to check
✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate

Choose Enhance MD

Feature-by-feature comparison

Feature	Call-On-Doc	Enhance MD
Monthly Price	$250	$212
Rating	7.9/10	7.7/10
Medications	semaglutide, tirzepatide, liraglutide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Mon-Fri 5am to midnight CT; weekends 6am to 1am CT	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Home delivery included in the $250 compounded semaglutide price	Medication shipped every 12 weeks
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Provider reviews at each visit; no fixed schedule published	Ongoing provider care and support included
Money-back Guarantee	None published	Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding
Cancellation Policy	Not published on the weight-loss pages	Plans run monthly or in 3+ month blocks; no separate cancellation policy published

Which should you choose?

Choose Call-On-Doc if you:

→Prefer a higher-rated service (7.9/10 vs 7.7/10)
→Want more medication options to choose from
→Value: a published, all-in price for the compounded semaglutide programme: $250.00 with home delivery included

Get started with Call-On-Doc

Choose Enhance MD if you:

→Want to save $38/month with a more affordable option
→Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Get started with Enhance MD

Website previews

Call-On-Doc

Call-On-Doc website

Enhance MD

Enhance MD website

Our recommendation

Call-On-Doc comes out ahead with a higher rating of 7.9/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Call-On-Doc

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