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Call-On-Doc vs Signos

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Call-On-Doc vs Signos: Overview

Choosing between Call-On-Doc and Signos for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Call-On-Doc offers both semaglutide and tirzepatide at $250/month with a rating of 7.9/10. Signos offers continuous glucose monitoring at $127/month with a 7.8/10 rating.

The price difference of $123/month is significant - Signos is the more budget-friendly option, while Call-On-Doc positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$123/mo

Rating Difference

0.1

Winner

Call-On-Doc

Best For

Quality

Call-On-Doc

View full Call-On-Doc review →

Rating

7.9/10Better

Monthly Price

$250

Medications

semaglutidetirzepatideliraglutide

Pros

✓A published, all-in price for the compounded semaglutide programme: $250.00 with home delivery included
✓Brand-name options are listed alongside compounded ones - Ozempic, Mounjaro, Saxenda, Wegovy, Zepbound and Contrave all appear in the medication catalogue
✓A published phone number, (214) 466-6618, plus email and text support - more contactable than most telehealth weight-loss services
✓Coverage across all 50 states plus the District of Columbia
✓Long service hours: Monday to Friday 5am to midnight CT, weekends 6am to 1am CT
✓No appointment needed - visits happen online when you start them
✓A "Subscribe & Save" programme brings general visits down to $12, useful if you use the service for more than weight loss
✓An RX Savings Card is offered to reduce prescription costs
✓Every programme includes a licensed provider visit that reviews your history and confirms the medication and dose

Cons

✗The $250 compounded semaglutide price is presented on the medication page, but the weight-loss programme pages do not carry a comparable published price for every option
✗Compounded medication is not FDA-approved and has not been reviewed by the FDA for safety, quality or efficacy
✗No refund or cancellation policy is published on the weight-loss pages
✗Insurance is not addressed on the weight-loss pages - this reads as a cash-pay service
✗Patient testimonials are duplicated verbatim across the page, which undermines their value as evidence
✗It is a broad urgent-care telehealth service first and a weight-loss provider second, so there is no dedicated coaching or nutrition programme
✗HSA/FSA acceptance is not stated

Choose Call-On-Doc

Signos

View full Signos review →

Rating

7.8/10

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Feature-by-feature comparison

Feature	Call-On-Doc	Signos
Monthly Price	$250	$127
Rating	7.9/10	7.8/10
Medications	semaglutide, tirzepatide, liraglutide	continuous glucose monitoring
Insurance Accepted	No	No
Support Hours	Mon-Fri 5am to midnight CT; weekends 6am to 1am CT	In-app dietitian chat; hours not published
Live Chat	No	Available
Free Shipping	Yes	Yes
Shipping Speed	Home delivery included in the $250 compounded semaglutide price	Free shipping; six-month plans ship in three-month bundles
Mobile App	No	Available
Dedicated Coach	Not included	Included
Follow-up Frequency	Provider reviews at each visit; no fixed schedule published	Continuous glucose data with in-app dietitian support
Money-back Guarantee	None published	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)
Cancellation Policy	Not published on the weight-loss pages	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused

Which should you choose?

Choose Call-On-Doc if you:

→Prefer a higher-rated service (7.9/10 vs 7.8/10)
→Want more medication options to choose from
→Value: a published, all-in price for the compounded semaglutide programme: $250.00 with home delivery included

Get started with Call-On-Doc

Choose Signos if you:

→Want to save $123/month with a more affordable option
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Website previews

Call-On-Doc

Call-On-Doc website

Signos

Signos website

Our recommendation

Call-On-Doc comes out ahead with a higher rating of 7.9/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Call-On-Doc

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