Circle Medical vs System Labs
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
These two prices are not directly comparable
- Circle Medical: the $35 figure is a per-visit consultation fee, not a month of treatment - the medication is billed separately.
Circle Medical vs System Labs: Overview
Choosing between Circle Medical and System Labs for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Circle Medical offers both semaglutide and tirzepatide at $35/month with a rating of 8.7/10. System Labs also provides both semaglutide and tirzepatide at $149/month with a 6.5/10 rating.
The price difference of $114/month is significant - Circle Medical is the more budget-friendly option, while System Labs positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$114/mo
Rating Difference
2.2
Winner
Circle Medical
Best For
Budget
Circle Medical
View full Circle Medical review →Rating
8.7/10Better
Monthly Price
$35Cheaper
Medications
semaglutidetirzepatideoral semaglutide
Pros
- ✓It bills your insurance instead of asking you to forget insurance exists. Circle Medical states it is in-network with most commercial plans
- ✓Publishes a real out-of-pocket figure rather than a marketing one: patients with accepted insurance paid an average of $35 per appointment over the previous six months
- ✓FDA-approved medication only - Wegovy, Zepbound and non-GLP-1 options such as Contrave when appropriate. No compounded product
- ✓No membership and no hidden fees, which is rare among insurance-accepting telehealth services
- ✓This is a full primary-care practice, so weight management sits inside ongoing medical care rather than being a standalone drug subscription
- ✓Clear, conventional eligibility criteria published up front: BMI 27+ with a weight-related condition such as high blood pressure, diabetes or sleep apnea, or BMI 30+ without one
- ✓A mobile app with regular provider check-ins
- ✓Honest about supply and coverage: the site warns these treatments have significant stock issues and are not always covered
- ✓Insurance verification is built into the booking flow, so you find out where you stand before the appointment
Cons
- ✗Your cost is whatever your plan says it is. $35 is an average, not a price - deductibles and exclusions can leave you paying far more
- ✗The medication itself is a separate cost from the visit, and coverage for weight-loss drugs is the single most commonly denied benefit in this category
- ✗You must live in the state you are treated in and have your primary pharmacy in that same state, which rules out anyone splitting time between states
- ✗The full list of available states is not published - you have to start booking an appointment to see it
- ✗You may be booked with any available provider (MD, DO, PA-C or NP) rather than choosing one
- ✗If your insurance denies weight-loss coverage, there is no cash-pay compounded fallback here
System Labs
View full System Labs review →Rating
6.5/10
Monthly Price
$149
Medications
NAD+sermorelinglutathioneMIC + B12GHK-Cu
Pros
- ✓Prices are published openly for every product, with the renewal rate shown alongside the introductory one: NAD+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, MIC + B12 $89/mo and GHK-Cu cream $109/mo (checked July 28, 2026)
- ✓Three delivery formats for NAD+ - injection, nasal spray and liposomal liquid - so needle-free options exist
- ✓Products are described as American made and third-party tested
- ✓The intake is short and a licensed provider reviews it before anything ships, with free 2-day shipping
- ✓No insurance required and no membership fee stacked on top of the product price
Cons
- ✗This is not a GLP-1 weight loss service. System Labs sells no semaglutide, no tirzepatide and no GLP-1 of any kind - the words do not appear anywhere on its site. If you are shopping for weight loss medication, this provider cannot supply it
- ✗We could not find any statement that the compounded peptides are not FDA-approved. That disclosure is standard across this category and its absence is the single biggest gap on the site
- ✗There is no refund or cancellation policy published at all - only a privacy policy and terms page
- ✗No independent review signal exists: no Trustpilot profile, no BBB file, and no rating displayed on site
- ✗Introductory pricing roughly doubles at renewal on most products, and the renewal price is the one you will pay for the rest of the course
- ✗Sermorelin, GHK-Cu and high-dose NAD+ have limited published human trial evidence for the benefits implied - 'perform 10 years younger' style claims are not supported by the kind of trials that back GLP-1 medications
- ✗No published phone number, support hours or physical address
- ✗The 'up to 1600mg' NAD+ potency claim is presented as an advantage without any evidence that higher doses produce better outcomes
Feature-by-feature comparison
| Feature | Circle Medical | System Labs |
|---|---|---|
| Monthly Price | $35 | $149 |
| Rating | 8.7/10 | 6.5/10 |
| Medications | semaglutide, tirzepatide, oral semaglutide | NAD+, sermorelin, glutathione, MIC + B12, GHK-Cu |
| Insurance Accepted | Yes | No |
| Support Hours | Not published | Medical team availability advertised; hours not published |
| Live Chat | No | Available |
| Free Shipping | No | Yes |
| Shipping Speed | Prescriptions go to your own pharmacy rather than shipping from the provider | Free 2-day shipping |
| Mobile App | Available | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Regular provider check-ins to monitor progress | Ongoing clinician support advertised; frequency not published |
| Money-back Guarantee | None published | None published |
| Cancellation Policy | Appointment-based care - there is no subscription to cancel | Not published |
Which should you choose?
Choose Circle Medical if you:
- →Want to save $114/month with a more affordable option
- →Prefer a higher-rated service (8.7/10 vs 6.5/10)
- →Need insurance coverage for your treatment
- →Value: it bills your insurance instead of asking you to forget insurance exists. circle medical states it is in-network with most commercial plans
Choose System Labs if you:
- →Want more medication options to choose from
- →Value: prices are published openly for every product, with the renewal rate shown alongside the introductory one: nad+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, mic + b12 $89/mo and ghk-cu cream $109/mo (checked july 28, 2026)
Website previews
Circle Medical
System Labs
Our recommendation
Circle Medical comes out ahead with a higher rating of 8.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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