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Direct Meds vs Willow

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Direct Meds vs Willow: Overview

Choosing between Direct Meds and Willow for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Direct Meds offers both semaglutide and tirzepatide at $297/month with a rating of 8/10. Willow also provides both semaglutide and tirzepatide at $299/month with a 7.4/10 rating.

With only a $2/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$2/mo

Rating Difference

0.6

Winner

Direct Meds

Best For

Budget

Direct Meds

View full Direct Meds review →

Rating

8/10Better

Monthly Price

$297Cheaper

Medications

semaglutidetirzepatide

Pros

✓The compounding explanation is genuinely educational, citing USP 795 and USP 797 and identifying the pharmacy as a 503A facility rather than hand-waving about 'FDA-registered' status
✓Trustpilot rating of 4.6 from 12,750 reviews, a large and credible independent sample
✓The FAQ states flat monthly prices with no membership layered on: $297/month for semaglutide and $399/month for tirzepatide (checked July 27, 2026)
✓That price is stated to include the medication, doctor visits normally billed at $99 each, next-day FedEx or UPS shipping, and all injection supplies
✓Same price at every dose, so titrating up does not increase the bill
✓A full refund is given if your prescription is not approved
✓A published customer phone number, 888-696-7176, which most competitors do not offer
✓This offer is restricted in only one state, Arkansas

Cons

✗The headline price and the real price do not match. The landing page leads with 'Starting at $147' while the FAQ on the same site states 'For Semaglutide we charge $297/month. For Tirzepatide we charge $399/month' - roughly double
✗Discounts are advertised in three different sizes on one page: '$150 Off Today', 'Up to $200 OFF' and 'Get $150 OFF your prescription instantly', with no terms attached to any of them
✗The 'patient satisfaction guarantee' is undefined - 'If you are unhappy with your results, let us know and we'll make it right' commits to nothing specific
✗The landing page uses the same template as several other compounded GLP-1 funnels, down to the identical headline 'The proven way to lose 15% of your body weight fast!'
✗'We've been featured all over' appears with no named publications or links
✗The '15% of your body weight' figure comes from trials of the branded drugs, not from Direct Meds' compounded product or its own patients
✗No BBB profile could be found to set against the Trustpilot score
✗Support hours are not published, only the phone number and an email address

Choose Direct Meds

Willow

View full Willow review →

Rating

7.4/10

Monthly Price

$299

Medications

semaglutidetirzepatide

Pros

✓Flat published pricing: $299/mo for compounded semaglutide as a weekly injection or a daily tablet, and $399/mo for compounded tirzepatide (checked July 26, 2026)
✓One fee covers the medical evaluation, the medication, unlimited doctor messaging and free discreet shipping, with no separate consultation charge
✓Names its partner pharmacies in its terms - Red Rock Home Pharmacy (Springville, UT), Epiq Pharmacy / Epiq Scripts (Richardson, TX) and The Pharmacy Hub (Miami, FL) - which most compounded GLP-1 sellers do not do
✓Publishes a Florida telehealth provider registration number (TPME1718) and names the exact states it is licensed to serve
✓The 'compounded drug products are not approved or evaluated for safety, effectiveness, or quality by the FDA' disclaimer sits on the homepage itself, not buried in a footer
✓Full refund if you cancel before the prescription is submitted to the pharmacy, processed within 5-10 business days
✓Needle-free daily tablets available for both semaglutide and tirzepatide, and the program is HSA/FSA eligible
✓Same-day prescription review claimed, with support from a named care team

Cons

✗In December 2025 the National Advertising Division found Willow had not substantiated its weight-loss and efficacy claims for compounded semaglutide, Willow declined to comply, and NAD referred it to state attorneys general and ad platforms. That is the most serious independent mark against any provider on this site
✗At $299-$399 a month this is one of the more expensive compounded GLP-1 programs; several competitors advertise $149-$199
✗The flat rate is not locked. The terms state your subscription fee 'may be increased or decreased if your prescription changes, such as by a dosage increase or frequency of refills', so titrating up can raise your bill
✗The site advertises '4.9/5 (2200 + 5 star reviews)' with no source named. Trustpilot, the one public platform we could find, showed 3.8 from 351 reviews on July 26, 2026
✗Cancellation must be received two full calendar days before your next shipping date, or the next order ships and bills
✗The terms tell you to cancel at startwillow.com/contact/ - that URL returned a 404 when we checked, as did the site's /contact and /help-center pages
✗No customer phone number or support email is published anywhere on the public site
✗The published terms are dated November 24, 2021, well before the current product line and pricing
✗Not available nationwide: Willow's terms limit service to 36 states, and this offer in particular is not available in Alabama, Alaska, Arkansas, Delaware, Kansas, Louisiana, Maine, Massachusetts, Mississippi, New Mexico, North Dakota, Rhode Island, South Dakota, Tennessee, Utah, Vermont, West Virginia or Wyoming
✗No insurance billing, and the terms confirm Medicare and Medicaid do not cover the service

Feature-by-feature comparison

Feature	Direct Meds	Willow
Monthly Price	$297	$299
Rating	8/10	7.4/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	24/7 online support claimed
Live Chat	Available	No
Free Shipping	Yes	Yes
Shipping Speed	Next-day FedEx or UPS; arrives in 1-2 days	Not published; same-day prescription review claimed
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	1:1 medical support with messaging and refills	Unlimited doctor messaging and free follow-ups claimed
Money-back Guarantee	Full refund if your prescription is not approved; a vaguely worded satisfaction guarantee otherwise	Full refund only if you cancel before the prescription reaches the pharmacy; no returns on medication once dispensed
Cancellation Policy	Cancel anytime, no monthly membership	Cancel anytime, but the request must arrive two full calendar days before your next shipping date

Which should you choose?

Choose Direct Meds if you:

→Want to save $2/month with a more affordable option
→Prefer a higher-rated service (8/10 vs 7.4/10)
→Value: the compounding explanation is genuinely educational, citing usp 795 and usp 797 and identifying the pharmacy as a 503a facility rather than hand-waving about 'fda-registered' status

Get started with Direct Meds

Choose Willow if you:

→Value: flat published pricing: $299/mo for compounded semaglutide as a weekly injection or a daily tablet, and $399/mo for compounded tirzepatide (checked july 26, 2026)

Get started with Willow

Website previews

Direct Meds

Direct Meds website

Willow

Willow website

Our recommendation

Direct Meds comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Direct Meds

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