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EllieMD vs System Labs

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

EllieMD vs System Labs: Overview

Choosing between EllieMD and System Labs for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

EllieMD offers both semaglutide and tirzepatide at $229/month with a rating of 7.2/10. System Labs also provides both semaglutide and tirzepatide at $149/month with a 6.5/10 rating.

The price difference of $80/month is significant - System Labs is the more budget-friendly option, while EllieMD positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$80/mo

Rating Difference

0.7

Winner

EllieMD

Best For

Quality

EllieMD

View full EllieMD review →

Rating

7.2/10Better

Monthly Price

$229

Medications

semaglutidetirzepatide

Pros

✓Published pricing for both microdose programmes: $229/month for the single-agonist GLP-1 ($687 total) and $239/month for the dual-agonist ($717 total)
✓No hidden membership, shipping or consultation fees, stated as a headline on the microdose page
✓Available in all 50 states
✓The partner pharmacy is named - Clover Pharmacy - and described as dispensing from 503A-compliant, state-licensed facilities
✓Payment is refunded if the medical provider determines you are not eligible for an EllieMD programme
✓24/7 access to a provider is included in the plan rather than sold as an upgrade
✓A state-licensed, board-certified MD, DO or qualified medical provider reviews your intake, and a phone call may be required rather than everything being asynchronous
✓The compounding disclaimer is explicit: compounded medications are not FDA-approved and the FDA does not review them for safety, efficacy or quality
✓It discloses that vial appearance, contents and dosage may vary based on your personalised prescription
✓Offers a paid 15-minute consultation with a wellness expert that comes with a $25 credit toward your next order

Cons

✗The whole proposition is microdosing, which has no controlled trial evidence behind it. Every published GLP-1 outcome - the 15% and 20% figures the category is built on - comes from full therapeutic doses
✗Both prices are quoted per month but billed as a multi-month total ($687 and $717), so the real commitment is three months up front
✗Compounded medication, not FDA-approved
✗The catalogue mixes prescription GLP-1s with Thymosin Alpha-1, hormone therapy, protein supplements and skincare, which blurs the line between medicine and wellness retail
✗The claim that "community support can double weight loss efficacy" is footnoted to a 2015 Northwestern citation and used to market a product that citation did not test
✗No phone number, support email or business address is published
✗No insurance billing and no HSA/FSA information
✗It is not clear from the site whether full therapeutic dosing is available at all, or only microdoses

System Labs

View full System Labs review →

Rating

6.5/10

Monthly Price

$149Cheaper

Medications

NAD+sermorelinglutathioneMIC + B12GHK-Cu

Pros

✓Prices are published openly for every product, with the renewal rate shown alongside the introductory one: NAD+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, MIC + B12 $89/mo and GHK-Cu cream $109/mo (checked July 28, 2026)
✓Three delivery formats for NAD+ - injection, nasal spray and liposomal liquid - so needle-free options exist
✓Products are described as American made and third-party tested
✓The intake is short and a licensed provider reviews it before anything ships, with free 2-day shipping
✓No insurance required and no membership fee stacked on top of the product price

Cons

✗This is not a GLP-1 weight loss service. System Labs sells no semaglutide, no tirzepatide and no GLP-1 of any kind - the words do not appear anywhere on its site. If you are shopping for weight loss medication, this provider cannot supply it
✗We could not find any statement that the compounded peptides are not FDA-approved. That disclosure is standard across this category and its absence is the single biggest gap on the site
✗There is no refund or cancellation policy published at all - only a privacy policy and terms page
✗No independent review signal exists: no Trustpilot profile, no BBB file, and no rating displayed on site
✗Introductory pricing roughly doubles at renewal on most products, and the renewal price is the one you will pay for the rest of the course
✗Sermorelin, GHK-Cu and high-dose NAD+ have limited published human trial evidence for the benefits implied - 'perform 10 years younger' style claims are not supported by the kind of trials that back GLP-1 medications
✗No published phone number, support hours or physical address
✗The 'up to 1600mg' NAD+ potency claim is presented as an advantage without any evidence that higher doses produce better outcomes

Choose System Labs

Feature-by-feature comparison

Feature	EllieMD	System Labs
Monthly Price	$229	$149
Rating	7.2/10	6.5/10
Medications	semaglutide, tirzepatide	NAD+, sermorelin, glutathione, MIC + B12, GHK-Cu
Insurance Accepted	No	No
Support Hours	Company advertises 24/7 support from doctors and specialists, included in the plan	Medical team availability advertised; hours not published
Live Chat	Available	Available
Free Shipping	Yes	Yes
Shipping Speed	Typically 2-10 business days; no shipping fees	Free 2-day shipping
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	24/7 direct access to a provider included in the plan	Ongoing clinician support advertised; frequency not published
Money-back Guarantee	Payment refunded if the medical provider determines you are not eligible	None published
Cancellation Policy	A refund and returns policy is published; multi-month programmes are billed as a total	Not published

Which should you choose?

Choose EllieMD if you:

→Prefer a higher-rated service (7.2/10 vs 6.5/10)
→Value: published pricing for both microdose programmes: $229/month for the single-agonist glp-1 ($687 total) and $239/month for the dual-agonist ($717 total)

Get started with EllieMD

Choose System Labs if you:

→Want to save $80/month with a more affordable option
→Want more medication options to choose from
→Value: prices are published openly for every product, with the renewal rate shown alongside the introductory one: nad+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, mic + b12 $89/mo and ghk-cu cream $109/mo (checked july 28, 2026)

Get started with System Labs

Website previews

EllieMD

EllieMD website

System Labs

System Labs website

Our recommendation

EllieMD comes out ahead with a higher rating of 7.2/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with EllieMD

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