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Fitish RX vs Signos

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Fitish RX vs Signos: Overview

Choosing between Fitish RX and Signos for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Fitish RX focuses on semaglutide at $219/month with a rating of 7.6/10. Signos offers continuous glucose monitoring at $127/month with a 7.8/10 rating.

The price difference of $92/month is significant - Signos is the more budget-friendly option, while Fitish RX positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$92/mo

Rating Difference

0.2

Winner

Signos

Best For

Budget

Fitish RX

View full Fitish RX review →

Rating

7.6/10

Monthly Price

$219

Medications

semaglutide

Pros

✓One number, everything in it: $219 for a monthly supply including the provider consult, the medication if approved, and shipping, with no separate consult or membership fees
✓A cheaper, honestly-labelled microdose lane at $179 a month for people who want a gentler approach - and it says outright that the microdose "does not titrate up"
✓It draws the distinction between the two lanes plainly rather than upselling: full dose for "serious, sustained weight management", microdose for a "gentle, mindful, cosmetic approach"
✓The compounding disclosure is unusually complete - it names the FDA-approved alternatives (Ozempic, Wegovy, Rybelsus) and states they are commercially available
✓A licensed provider reviews every intake, and the care team stays reachable through the patient portal for dose questions at no added cost
✓Medication ships monthly from a state-licensed sterile compounding pharmacy
✓Payment plans are offered (five payments of $43.80 shown on the product page)
✓Free standard shipping on orders over $100

Cons

✗Compounded semaglutide is not FDA-approved and does not undergo FDA review for safety, effectiveness or manufacturing quality
✗The microdosing lane is marketed for cosmetic weight loss, which is not an evidence-based clinical indication - no trial has tested fixed sub-therapeutic semaglutide dosing for that purpose
✗Only semaglutide. There is no tirzepatide option, so if semaglutide does not suit you there is nowhere to go inside the service
✗No phone number is published
✗The dispensing pharmacy is described only as "a state licensed sterile compounding pharmacy" and is never named
✗No refund, cancellation or money-back policy is published on the product page
✗No insurance billing and no HSA/FSA guidance
✗Marketed specifically to women, which is a positioning choice rather than a clinical one

Choose Fitish RX

Signos

View full Signos review →

Rating

7.8/10Better

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Feature-by-feature comparison

Feature	Fitish RX	Signos
Monthly Price	$219	$127
Rating	7.6/10	7.8/10
Medications	semaglutide	continuous glucose monitoring
Insurance Accepted	No	No
Support Hours	Patient portal messaging; hours not published	In-app dietitian chat; hours not published
Live Chat	No	Available
Free Shipping	Yes	Yes
Shipping Speed	Free standard shipping on all orders over $100; monthly cadence	Free shipping; six-month plans ship in three-month bundles
Mobile App	No	Available
Dedicated Coach	Not included	Included
Follow-up Frequency	Ongoing care-team access through the patient portal at no added cost	Continuous glucose data with in-app dietitian support
Money-back Guarantee	None published	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)
Cancellation Policy	Not published	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused

Which should you choose?

Choose Fitish RX if you:

→Value: one number, everything in it: $219 for a monthly supply including the provider consult, the medication if approved, and shipping, with no separate consult or membership fees

Get started with Fitish RX

Choose Signos if you:

→Want to save $92/month with a more affordable option
→Prefer a higher-rated service (7.8/10 vs 7.6/10)
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Website previews

Fitish RX

Fitish RX website

Signos

Signos website

Our recommendation

Signos comes out ahead with a higher rating of 7.8/10.

Get started with Signos

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