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HealthRX vs System Labs

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

HealthRX vs System Labs: Overview

Choosing between HealthRX and System Labs for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

HealthRX offers both semaglutide and tirzepatide at $133/month with a rating of 8.5/10. System Labs also provides both semaglutide and tirzepatide at $149/month with a 6.5/10 rating.

With only a $16/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$16/mo

Rating Difference

2.0

Winner

HealthRX

Best For

Budget

HealthRX

View full HealthRX review →

Rating

8.5/10Better

Monthly Price

$133Cheaper

Medications

semaglutidetirzepatide

Pros

✓Efficacy claims are cited to the actual trials with duration and source: 'Average 15% body-weight loss at 68 weeks in STEP-1' for semaglutide and 'Average 21% body-weight loss at 72 weeks in pivotal phase-3 trial' for tirzepatide, referencing NEJM 2021, each followed immediately by 'Not FDA-approved'
✓The competitor price comparison is dated and sourced - 'published monthly prices at comparable telehealth clinics, July 2026' and 'Prices as displayed on each clinic's public site' - rather than an unattributed claim of being cheapest
✓LegitScript certification is given with its certificate number (50087439), so it can be independently verified
✓Pricing is low and clearly tiered: compounded semaglutide from $133/mo on a 3-month plan or $99/mo on 12 months, and tirzepatide from $209/mo or $179/mo on 12 months (checked July 27, 2026)
✓Same price at every dose, so titration does not raise the bill
✓Full refund if a licensed provider does not approve you, and the site states outright that paying does not guarantee a prescription
✓Cancel anytime 'in one click', with free overnight cold-chain shipping and availability in all 50 states
✓The 503A regulatory category is named specifically rather than the vaguer 'FDA-registered facility' language competitors prefer

Cons

✗The '4.8 · 12,000+ members' rating shown in the header has no traceable source - we found no Trustpilot profile for the domain and no other public review platform carrying it
✗The advertised prices are plan prices, not month-to-month rates. '$133/mo' is the 3-month plan and '$99/mo' requires committing to a full year; no single-month price is displayed
✗Committing 12 months upfront to a compounded medication means paying for a year before you know how you tolerate it
✗No BBB profile or independent complaint record exists to check the service against
✗No published customer phone number or support hours
✗The competitor comparison, while dated and sourced, is still marketing produced by the company that benefits from it
✗As with every compounded GLP-1, the trial figures quoted come from the branded medicines rather than the compounded product actually dispensed - HealthRX says so, but the numbers still headline the page

Choose HealthRX

System Labs

View full System Labs review →

Rating

6.5/10

Monthly Price

$149

Medications

NAD+sermorelinglutathioneMIC + B12GHK-Cu

Pros

✓Prices are published openly for every product, with the renewal rate shown alongside the introductory one: NAD+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, MIC + B12 $89/mo and GHK-Cu cream $109/mo (checked July 28, 2026)
✓Three delivery formats for NAD+ - injection, nasal spray and liposomal liquid - so needle-free options exist
✓Products are described as American made and third-party tested
✓The intake is short and a licensed provider reviews it before anything ships, with free 2-day shipping
✓No insurance required and no membership fee stacked on top of the product price

Cons

✗This is not a GLP-1 weight loss service. System Labs sells no semaglutide, no tirzepatide and no GLP-1 of any kind - the words do not appear anywhere on its site. If you are shopping for weight loss medication, this provider cannot supply it
✗We could not find any statement that the compounded peptides are not FDA-approved. That disclosure is standard across this category and its absence is the single biggest gap on the site
✗There is no refund or cancellation policy published at all - only a privacy policy and terms page
✗No independent review signal exists: no Trustpilot profile, no BBB file, and no rating displayed on site
✗Introductory pricing roughly doubles at renewal on most products, and the renewal price is the one you will pay for the rest of the course
✗Sermorelin, GHK-Cu and high-dose NAD+ have limited published human trial evidence for the benefits implied - 'perform 10 years younger' style claims are not supported by the kind of trials that back GLP-1 medications
✗No published phone number, support hours or physical address
✗The 'up to 1600mg' NAD+ potency claim is presented as an advantage without any evidence that higher doses produce better outcomes

Choose System Labs

Feature-by-feature comparison

Feature	HealthRX	System Labs
Monthly Price	$133	$149
Rating	8.5/10	6.5/10
Medications	semaglutide, tirzepatide	NAD+, sermorelin, glutathione, MIC + B12, GHK-Cu
Insurance Accepted	No	No
Support Hours	Not published	Medical team availability advertised; hours not published
Live Chat	No	Available
Free Shipping	Yes	Yes
Shipping Speed	Free overnight shipping, ships cold in 24-48 hours	Free 2-day shipping
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Provider review and ongoing support included	Ongoing clinician support advertised; frequency not published
Money-back Guarantee	Full refund if a licensed provider does not approve you for treatment	None published
Cancellation Policy	Cancel anytime in one click; plan prices are paid upfront for the term selected	Not published

Which should you choose?

Choose HealthRX if you:

→Want to save $16/month with a more affordable option
→Prefer a higher-rated service (8.5/10 vs 6.5/10)
→Value: efficacy claims are cited to the actual trials with duration and source: 'average 15% body-weight loss at 68 weeks in step-1' for semaglutide and 'average 21% body-weight loss at 72 weeks in pivotal phase-3 trial' for tirzepatide, referencing nejm 2021, each followed immediately by 'not fda-approved'

Get started with HealthRX

Choose System Labs if you:

→Want more medication options to choose from
→Value: prices are published openly for every product, with the renewal rate shown alongside the introductory one: nad+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, mic + b12 $89/mo and ghk-cu cream $109/mo (checked july 28, 2026)

Get started with System Labs

Website previews

HealthRX

HealthRX website

System Labs

System Labs website

Our recommendation

HealthRX comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with HealthRX

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