← All providers

LifeMD vs Sesame Care

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

LifeMD vs Sesame Care: Overview

Choosing between LifeMD and Sesame Care for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

LifeMD offers both semaglutide and tirzepatide at $199/month with a rating of 8.5/10. Sesame Care also provides both semaglutide and tirzepatide at $59/month with a 8.7/10 rating.

The price difference of $140/month is significant - Sesame Care is the more budget-friendly option, while LifeMD positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$140/mo

Rating Difference

0.2

Winner

Sesame Care

Best For

Budget

LifeMD

View full LifeMD review →

Rating

8.5/10

Monthly Price

$199

Medications

semaglutidetirzepatide

Pros

✓Prescribes FDA-approved branded GLP-1s - Zepbound and Wegovy - rather than compounded preparations, so you get the exact product the trials studied
✓Accepts insurance including Medicare, and advertises as low as $0 copay for branded GLP-1s where coverage applies
✓Publishes cash prices too: Wegovy Pen from $199/month and Zepbound Vial from $349/month (checked July 28, 2026)
✓Offers an outcome-based guarantee: 'lose 10% of your weight or your money back', which ties the promise to a result rather than a satisfaction survey
✓HSA and FSA eligible
✓Weight care sits inside a full telehealth service, so urgent care, labs and other specialties are available under the same account

Cons

✗The rotating banner on the weight-management page shows the Wegovy Pen at both '$199' and '$499' in the same carousel, which makes the real starting price unclear before you sign up
✗The money-back guarantee carries a footnote marker on site, so read the qualifying conditions before relying on it
✗Insurance coverage for obesity medication is patchy, so the '$0 copay' outcome will not apply to many people and the cash prices are what you should plan around
✗A 4.0 Trustpilot average is mid-range for this category
✗Branded GLP-1s at $199-$349/month are more expensive than compounded alternatives, which is the trade-off for using an FDA-approved product
✗GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy

Sesame Care

View full Sesame Care review →

Rating

8.7/10Better

Monthly Price

$59Cheaper

Medications

semaglutidetirzepatideorforglipron

Pros

✓Publishes cash prices dose by dose, which no other provider on this site does. Zepbound KwikPen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
✓The same detail applies across the range: Wegovy pill $149/mo (1.5mg, 4mg) or $299 (9mg, 25mg); Wegovy pen $199 for the first two months for new patients then $349; Foundayo from $149 to $349 depending on dose (checked July 27, 2026)
✓Every medication offered is FDA-approved and branded - no compounded product is involved
✓Insurance is accepted, and with coverage medication can drop to as low as $25/mo
✓The care programme itself - video visits, dedicated provider, labs and messaging - starts at $59/mo
✓Efficacy milestones are properly sourced, citing a study of injectable semaglutide 2.4mg with the population spelled out (BMI 30+, or 27+ with a weight-related condition, non-diabetic) and paired with lifestyle change
✓A full refund is available if you cancel at least three hours before your first visit
✓The wider marketplace lets you compare individual providers on price, with appointments from $37

Cons

✗The $59/mo headline depends on a 12-month 'Success by Sesame' commitment, and the annual fee is explicitly non-refundable once paid - cancel in month two and you do not get the remaining ten months back
✗Medication costs are not included in the programme price, which Sesame states plainly but which means the real monthly outlay is the subscription plus the drug
✗Cash prices escalate steeply with dose. Zepbound more than doubles from $299 to $698 as you titrate to a maintenance dose, so the entry price is not the price you will end up paying
✗The Wegovy pen intro rate of $199 applies to new patients only and for two months, after which it is $349
✗Monthly subscribers are not refunded for months already paid, even if unused
✗Because pricing depends on insurance status, pharmacy and dose, there is no single figure you can plan around before signing up
✗This is a general healthcare marketplace, so the weight-loss programme sits alongside urgent care and prescription refills rather than being a dedicated speciality service

Choose Sesame Care

Feature-by-feature comparison

Feature	LifeMD	Sesame Care
Monthly Price	$199	$59
Rating	8.5/10	8.7/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide, orforglipron
Insurance Accepted	Yes	Yes
Support Hours	Mon-Fri 8AM-8PM ET	Not published
Live Chat	Available	No
Free Shipping	Yes	No
Shipping Speed	3-5 days	Filled at your pharmacy; not shipped by Sesame
Mobile App	Available	Available
Dedicated Coach	Not included	Included
Follow-up Frequency	Quarterly	Ongoing video visits, labs and messaging with a dedicated provider
Money-back Guarantee	Lose 10% of your weight or your money back (conditions apply)	Full refund if you cancel at least 3 hours before your first visit; annual fees are non-refundable once paid
Cancellation Policy	Cancel anytime	Self-cancel monthly or annual subscriptions any time, but past months and annual fees are not refunded

Which should you choose?

Choose LifeMD if you:

→Value: prescribes fda-approved branded glp-1s - zepbound and wegovy - rather than compounded preparations, so you get the exact product the trials studied

Get started with LifeMD

Choose Sesame Care if you:

→Want to save $140/month with a more affordable option
→Prefer a higher-rated service (8.7/10 vs 8.5/10)
→Want more medication options to choose from
→Want personalized coaching support included
→Value: publishes cash prices dose by dose, which no other provider on this site does. zepbound kwikpen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start

Get started with Sesame Care

Website previews

LifeMD

LifeMD website

Sesame Care

Sesame Care website

Our recommendation

Sesame Care comes out ahead with a higher rating of 8.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Sesame Care

Related comparisons

LifeMD vs CoreAge Rx

LifeMD vs Zepbound

LifeMD vs Mounjaro

LifeMD vs Wegovy Pill

LifeMD vs Foundayo

LifeMD vs Wegovy

LifeMD vs NovoCare Pharmacy

LifeMD vs Ozempic

LifeMD vs Form Health

LifeMD vs Henry Meds

LifeMD vs FuturHealth

LifeMD vs Circle Medical

LifeMD vs Ro

LifeMD vs Midi Health

LifeMD vs Noom Med

LifeMD vs Precision Telemed

LifeMD vs Hims

LifeMD vs Calibrate

LifeMD vs PlushCare

LifeMD vs Ascend Medical

Compare other providers

Compare GLP-1 Brands

First Brand

vs

Second Brand