Likeness Rx vs Signos
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Likeness Rx vs Signos: Overview
Choosing between Likeness Rx and Signos for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Likeness Rx offers both semaglutide and tirzepatide at $79/month with a rating of 0/10. Signos offers continuous glucose monitoring at $127/month with a 7.8/10 rating.
With only a $48/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 149 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $79/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$48/mo
Rating Difference
7.8
Winner
Signos
Best For
Quality
Likeness Rx
View full Likeness Rx review →Rating
0/10
Monthly Price
$79Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓Semaglutide from $79/month; tirzepatide from $129/month
- ✓Online provider review; prescription required
- ✓GLP-1 and prescription skincare options
Cons
- ✗These are provider-published terms checked October 4, 2026. Prescription approval is conditional. Compounded medications are not FDA-approved; we have not tested the treatment, pharmacy fulfillment or patient outcomes.
- ✗The lowest monthly equivalents accompany 12-month subscriptions: $948 for semaglutide or $1,548 for tirzepatide. One-month plans are $139 and $199. The page says the selected term renews automatically; check the amount due and cancellation date.
Signos
View full Signos review →Rating
7.8/10Better
Monthly Price
$127
Medications
continuous glucose monitoring
Pros
- ✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
- ✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
- ✓Two CGM sensors per month are included in every plan
- ✓HSA/FSA eligible, which matters at these prices
- ✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
- ✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
- ✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
- ✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
- ✓Stress and sleep tracking are built in alongside glucose
Cons
- ✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
- ✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
- ✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
- ✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
- ✗The results guarantee pays out in a free data audit, not money back
- ✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
- ✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm
Feature-by-feature comparison
| Feature | Likeness Rx | Signos |
|---|---|---|
| Monthly Price | $79 | $127 |
| Rating | 0/10 | 7.8/10 |
| Medications | semaglutide, tirzepatide | continuous glucose monitoring |
| Insurance Accepted | No | No |
| Support Hours | Confirm directly with the provider | In-app dietitian chat; hours not published |
| Live Chat | No | Available |
| Free Shipping | Yes | Yes |
| Shipping Speed | The site advertises shipment within two business days after approval; not independently tested. | Free shipping; six-month plans ship in three-month bundles |
| Mobile App | No | Available |
| Dedicated Coach | Not included | Included |
| Follow-up Frequency | Confirm directly with the provider | Continuous glucose data with in-app dietitian support |
| Money-back Guarantee | The site advertises a refund if a prescription is not approved; check the selected order policy. | 30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value) |
| Cancellation Policy | The lowest monthly equivalents accompany 12-month subscriptions: $948 for semaglutide or $1,548 for tirzepatide. One-month plans are $139 and $199. The page says the selected term renews automatically; check the amount due and cancellation date. | Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused |
Which should you choose?
Choose Likeness Rx if you:
- →Want to save $48/month with a more affordable option
- →Want more medication options to choose from
- →Value: semaglutide from $79/month; tirzepatide from $129/month
Choose Signos if you:
- →Prefer a higher-rated service (7.8/10 vs 0/10)
- →Want personalized coaching support included
- →Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
Website previews
Likeness Rx
Signos
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