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Live Vital vs Shameless Care

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Live Vital vs Shameless Care: Overview

Choosing between Live Vital and Shameless Care for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Live Vital offers both semaglutide and tirzepatide at $149/month with a rating of 6.4/10. Shameless Care also provides both semaglutide and tirzepatide at $109/month with a 8/10 rating.

With only a $40/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$40/mo

Rating Difference

1.6

Winner

Shameless Care

Best For

Budget

Live Vital

View full Live Vital review →

Rating

6.4/10

Monthly Price

$149

Medications

tesamorelinMOTS-cBPC-157TB-500CJC-1295/IpamorelinNAD+GHK-Cuglutathione

Pros

✓Every protocol is priced openly on one page: glutathione $66/mo, NAD+ $83/mo, GHK-Cu $99/mo, Wolverine and CJC-1295/Ipamorelin $116/mo, Glow, Klow and MOTS-c $149/mo, tesamorelin $166/mo (checked July 28, 2026)
✓A named, identifiable physician stands behind the service, and a free 15-minute phone consult with him is offered before you buy
✓It publishes a dedicated peptide therapy informed consent document covering risks, benefits and alternatives - genuinely rare in this corner of the market
✓Telehealth consent and a HIPAA notice are published alongside the usual terms and privacy policy
✓Products are prescribed after a medical intake and prepared by a licensed US pharmacy, with unlimited messaging included
✓Available in all 50 states, per the company

Cons

✗This is not a GLP-1 weight loss service. Live Vital sells no semaglutide and no tirzepatide - its 'Weight & metabolism' line is tesamorelin and MOTS-c, which work through entirely different mechanisms
✗Two of its headline ingredients, BPC-157 and TB-500, were placed by the FDA on its 503A Category 2 list - bulk substances identified as raising significant safety risks in compounding. They appear here both standalone and inside the Glow, Klow and Wolverine blends
✗MOTS-c and KPV have essentially no published human trial evidence for the benefits described, yet MOTS-c is sold as a weight and metabolism protocol at $149/mo
✗Tesamorelin is described as 'An FDA-studied analog that targets stubborn abdominal fat'. Its actual FDA approval is for HIV-associated lipodystrophy specifically, not general abdominal fat, and the compounded version sold here is not the approved product
✗We could not find any statement that these compounded peptides are not FDA-approved
✗No refund or cancellation policy appears among the published legal documents
✗No independent review record exists - no Trustpilot profile, no BBB file, no displayed rating
✗No published phone number or support hours beyond the booked consult

Choose Live Vital

Shameless Care

View full Shameless Care review →

Rating

8/10Better

Monthly Price

$109Cheaper

Medications

sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline

Pros

✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost

Cons

✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
✗Not available in all 50 states - the site states 49
✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron

Choose Shameless Care

Feature-by-feature comparison

Feature	Live Vital	Shameless Care
Monthly Price	$149	$109
Rating	6.4/10	8/10
Medications	tesamorelin, MOTS-c, BPC-157, TB-500, CJC-1295/Ipamorelin, NAD+, GHK-Cu, glutathione	sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Not published	Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Unlimited messaging with the care team	Board-certified physician assigned from start to finish; ongoing cadence not published
Money-back Guarantee	None published	Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published
Cancellation Policy	Not published among the legal documents	No subscriptions - every purchase is one-off, so there is nothing to cancel

Which should you choose?

Choose Live Vital if you:

→Want more medication options to choose from
→Value: every protocol is priced openly on one page: glutathione $66/mo, nad+ $83/mo, ghk-cu $99/mo, wolverine and cjc-1295/ipamorelin $116/mo, glow, klow and mots-c $149/mo, tesamorelin $166/mo (checked july 28, 2026)

Get started with Live Vital

Choose Shameless Care if you:

→Want to save $40/month with a more affordable option
→Prefer a higher-rated service (8/10 vs 6.4/10)
→Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)

Get started with Shameless Care

Website previews

Live Vital

Live Vital website

Shameless Care

Shameless Care website

Our recommendation

Shameless Care comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Shameless Care

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