Luvo Health vs Signos
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Luvo Health vs Signos: Overview
Choosing between Luvo Health and Signos for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
Luvo Health offers both semaglutide and tirzepatide at $249/month with a rating of 8.1/10. Signos offers continuous glucose monitoring at $127/month with a 7.8/10 rating.
The price difference of $122/month is significant - Signos is the more budget-friendly option, while Luvo Health positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$122/mo
Rating Difference
0.3
Winner
Luvo Health
Best For
Quality
Luvo Health
View full Luvo Health review →Rating
8.1/10Better
Monthly Price
$249
Medications
semaglutidetirzepatideNAD+sermorelinestradiolenclomiphene
Pros
- ✓The entire price ladder is published with no intake required, and it shows the per-week equivalent alongside the total: compounded semaglutide injection $249 for 4 weeks ($62/week), tirzepatide injection $339 ($85/week), semaglutide tablets $279 ($70/week) - checked July 28, 2026
- ✓Longer commitments cut the rate substantially: semaglutide injection falls to $55/week over 12 weeks, $50/week over 24 and $45/week over 52
- ✓One flat price with no membership fee - medication and provider visits are included rather than billed separately, which is the trap several competitors in this space rely on
- ✓Branded Ozempic is offered alongside the compounded options at $1,299 for 4 weeks, so you can choose the FDA-approved drug if you would rather not use a compounded preparation
- ✓'Compounded medications are not FDA-approved' appears on every single medication page, not just in the site footer
- ✓The NAD+ page is unusually honest about its own product: 'Clinics sometimes offer NAD+ therapies as part of wellness programs, although evidence for many longevity claims is still emerging.' Almost no competitor in the longevity space concedes that
- ✓Full refund if a provider disqualifies you for a medical reason before medication is ordered
- ✓Cancel at any time, with no commitment until a clinician has reviewed your intake
- ✓The longevity line is cheap relative to the category - NAD+ injection and sermorelin both start at $34/week - and NAD+ comes in three routes: injection, oral drops and nasal spray
- ✓A genuinely broad catalogue under one provider: weight loss, longevity, hormone replacement (estradiol in five formats), testosterone support (enclomiphene, gonadorelin) and prescription skincare
Cons
- ✗There is no Trustpilot profile and no BBB record, so there is no independent evidence about what the service is actually like. For a provider asking upwards of $2,000 for a year's supply, that is a real gap
- ✗The best rates require large upfront commitments. The $45/week semaglutide price means paying $2,327 for 52 weeks, and the refund policy only guarantees money back if a clinician disqualifies you before medication is ordered
- ✗You are charged for the first month as soon as you complete the intake form, before you know whether you will be approved
- ✗A separate 'Microdosing' programme is offered. Microdosing GLP-1s is not an evidence-based protocol - the trials behind these drugs used full therapeutic doses
- ✗The LegitScript certification claimed in the company's partner materials is not evidenced anywhere on its own site
- ✗Sermorelin is priced and promoted alongside NAD+, but the site does not extend the same 'evidence is still emerging' caveat to it, even though human outcome data for sermorelin in healthy adults is similarly thin
- ✗No published phone number - support runs through email and your account
- ✗Ozempic at $1,299 for four weeks is close to full list price, so the branded option is only realistic if you have no insurance route and specifically want the approved drug
- ✗Compounded semaglutide and tirzepatide are not FDA-approved, and the weight-loss figures associated with these molecules come from trials of the branded products, not compounded versions
Signos
View full Signos review →Rating
7.8/10
Monthly Price
$127Cheaper
Medications
continuous glucose monitoring
Pros
- ✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
- ✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
- ✓Two CGM sensors per month are included in every plan
- ✓HSA/FSA eligible, which matters at these prices
- ✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
- ✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
- ✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
- ✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
- ✓Stress and sleep tracking are built in alongside glucose
Cons
- ✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
- ✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
- ✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
- ✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
- ✗The results guarantee pays out in a free data audit, not money back
- ✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
- ✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm
Feature-by-feature comparison
| Feature | Luvo Health | Signos |
|---|---|---|
| Monthly Price | $249 | $127 |
| Rating | 8.1/10 | 7.8/10 |
| Medications | semaglutide, tirzepatide, NAD+, sermorelin, estradiol, enclomiphene | continuous glucose monitoring |
| Insurance Accepted | No | No |
| Support Hours | Not published | In-app dietitian chat; hours not published |
| Live Chat | No | Available |
| Free Shipping | Yes | Yes |
| Shipping Speed | Shipped to your door after clinician review | Free shipping; six-month plans ship in three-month bundles |
| Mobile App | No | Available |
| Dedicated Coach | Not included | Included |
| Follow-up Frequency | Ongoing clinician contact with dose adjustments as the plan evolves | Continuous glucose data with in-app dietitian support |
| Money-back Guarantee | Full refund if a provider disqualifies you for a medical reason before medication is ordered | 30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value) |
| Cancellation Policy | Cancel at any time via support@luvohealth.com or your account; first month is charged once the intake form is completed | Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused |
Which should you choose?
Choose Luvo Health if you:
- →Prefer a higher-rated service (8.1/10 vs 7.8/10)
- →Want more medication options to choose from
- →Value: the entire price ladder is published with no intake required, and it shows the per-week equivalent alongside the total: compounded semaglutide injection $249 for 4 weeks ($62/week), tirzepatide injection $339 ($85/week), semaglutide tablets $279 ($70/week) - checked july 28, 2026
Choose Signos if you:
- →Want to save $122/month with a more affordable option
- →Want personalized coaching support included
- →Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
Website previews
Luvo Health
Signos
Our recommendation
Luvo Health comes out ahead with a higher rating of 8.1/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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