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MEDVi Quad vs PlushCare

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

MEDVi Quad vs PlushCare: Overview

Choosing between MEDVi Quad and PlushCare for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

MEDVi Quad offers both semaglutide and tirzepatide at $114/month with a rating of 6.5/10. PlushCare also provides both semaglutide and tirzepatide at $20/month with a 8.5/10 rating.

The price difference of $94/month is significant - PlushCare is the more budget-friendly option, while MEDVi Quad positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$94/mo

Rating Difference

2.0

Winner

PlushCare

Best For

Budget

MEDVi Quad

View full MEDVi Quad review →

Rating

6.5/10

Monthly Price

$114

Medications

sildenafiltadalafilbremelanotide (PT-141)L-citrulline

Pros

✓$114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked July 28, 2026)
✓Cancel anytime, and the page states you are not charged if you do not qualify
✓All four active ingredients are named openly - PT-141 (bremelanotide), L-citrulline, sildenafil and tadalafil - rather than hidden behind a proprietary blend name
✓Sublingual delivery is a real advantage over tablets: it bypasses first-pass metabolism, so onset is faster and a heavy meal does not blunt absorption the way it can with oral sildenafil
✓Backed by a substantial independent review record - roughly 14,000 Trustpilot reviews at 4.4, with 99% of negative reviews answered
✓A published phone number, email address and physical address, which many competitors in this category omit entirely

Cons

✗'Peak rigidity guaranteed' appears directly in the product copy. No prescription medication can guarantee an outcome, and this is the most explicit outcome promise we have seen across every provider reviewed on this site
✗The formula stacks two PDE5 inhibitors - sildenafil and tadalafil - and then adds L-citrulline, a nitric oxide precursor. All three act on the same nitric oxide and cGMP pathway, so the blood-pressure-lowering effect compounds three ways rather than one
✗PT-141 adds a fourth agent that independently causes low blood pressure, nausea and flushing. Four actives, four routes to hypotension, and no discussion anywhere on the page of the combined risk
✗Bremelanotide's only FDA approval is as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Prescribing it to men in a compounded sublingual liquid is off-label and a different route of administration
✗The word FDA does not appear on the page at all. The product is compounded, and the page never states the consequence - that compounded preparations are not reviewed or approved by the FDA for safety, efficacy or quality
✗'The world's first 4-in-1 formula' and 'hospital-grade power' are unverifiable marketing superlatives attached to a prescription product
✗The advertised Trustpilot score covers MEDVi's business as a whole rather than this specific product
✗The published address is a suite at a Delaware registered-agent building, not a clinical facility
✗Anyone taking nitrates or riociguat must not use this product. The PT-141 component also interacts with 5-HT3 anti-emetics such as ondansetron, and stacking two PDE5 inhibitors makes the nitrate contraindication more dangerous, not less

Choose MEDVi Quad

PlushCare

View full PlushCare review →

Rating

8.5/10Better

Monthly Price

$20Cheaper

Medications

semaglutidetirzepatideliraglutide

Pros

✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
✓Membership is $19.99/month with the first month free, and there is no minimum commitment
✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
✓A full refund is offered if the doctor is unable to treat you
✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure

Cons

✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site

Choose PlushCare

Feature-by-feature comparison

Feature	MEDVi Quad	PlushCare
Monthly Price	$114	$20
Rating	6.5/10	8.5/10
Medications	sildenafil, tadalafil, bremelanotide (PT-141), L-citrulline	semaglutide, tirzepatide, liraglutide
Insurance Accepted	No	Yes
Support Hours	24/7 medical support advertised	Video visits available 24/7
Live Chat	No	No
Free Shipping	Yes	No
Shipping Speed	Free rush shipping included in the monthly price	Filled at your pharmacy; not shipped by PlushCare
Mobile App	No	Available
Dedicated Coach	Not included	Not included
Follow-up Frequency	24/7 medical support advertised; follow-up cadence not published	Ongoing management with a board-certified primary care physician
Money-back Guarantee	No charge if you do not qualify; no refund policy published for dispensed medication	Full refund if the doctor is unable to treat you; medication and lab costs are never included
Cancellation Policy	Cancel anytime	Cancel anytime, no minimum commitment; first month of membership is free

Which should you choose?

Choose MEDVi Quad if you:

→Want more medication options to choose from
→Value: $114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked july 28, 2026)

Get started with MEDVi Quad

Choose PlushCare if you:

→Want to save $94/month with a more affordable option
→Prefer a higher-rated service (8.5/10 vs 6.5/10)
→Need insurance coverage for your treatment
→Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit

Get started with PlushCare

Website previews

MEDVi Quad

MEDVi Quad website

PlushCare

PlushCare website

Our recommendation

PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with PlushCare

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