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MEDVi Quad vs TRT Nation

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

MEDVi Quad vs TRT Nation: Overview

Choosing between MEDVi Quad and TRT Nation for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

MEDVi Quad offers both semaglutide and tirzepatide at $114/month with a rating of 6.5/10. TRT Nation offers tirzepatide at $219/month with a 7.5/10 rating.

The price difference of $105/month is significant - MEDVi Quad is the more budget-friendly option, while TRT Nation positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$105/mo

Rating Difference

1.0

Winner

TRT Nation

Best For

Quality

MEDVi Quad

View full MEDVi Quad review →

Rating

6.5/10

Monthly Price

$114Cheaper

Medications

sildenafiltadalafilbremelanotide (PT-141)L-citrulline

Pros

✓$114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked July 28, 2026)
✓Cancel anytime, and the page states you are not charged if you do not qualify
✓All four active ingredients are named openly - PT-141 (bremelanotide), L-citrulline, sildenafil and tadalafil - rather than hidden behind a proprietary blend name
✓Sublingual delivery is a real advantage over tablets: it bypasses first-pass metabolism, so onset is faster and a heavy meal does not blunt absorption the way it can with oral sildenafil
✓Backed by a substantial independent review record - roughly 14,000 Trustpilot reviews at 4.4, with 99% of negative reviews answered
✓A published phone number, email address and physical address, which many competitors in this category omit entirely

Cons

✗'Peak rigidity guaranteed' appears directly in the product copy. No prescription medication can guarantee an outcome, and this is the most explicit outcome promise we have seen across every provider reviewed on this site
✗The formula stacks two PDE5 inhibitors - sildenafil and tadalafil - and then adds L-citrulline, a nitric oxide precursor. All three act on the same nitric oxide and cGMP pathway, so the blood-pressure-lowering effect compounds three ways rather than one
✗PT-141 adds a fourth agent that independently causes low blood pressure, nausea and flushing. Four actives, four routes to hypotension, and no discussion anywhere on the page of the combined risk
✗Bremelanotide's only FDA approval is as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Prescribing it to men in a compounded sublingual liquid is off-label and a different route of administration
✗The word FDA does not appear on the page at all. The product is compounded, and the page never states the consequence - that compounded preparations are not reviewed or approved by the FDA for safety, efficacy or quality
✗'The world's first 4-in-1 formula' and 'hospital-grade power' are unverifiable marketing superlatives attached to a prescription product
✗The advertised Trustpilot score covers MEDVi's business as a whole rather than this specific product
✗The published address is a suite at a Delaware registered-agent building, not a clinical facility
✗Anyone taking nitrates or riociguat must not use this product. The PT-141 component also interacts with 5-HT3 anti-emetics such as ondansetron, and stacking two PDE5 inhibitors makes the nitrate contraindication more dangerous, not less

Choose MEDVi Quad

TRT Nation

View full TRT Nation review →

Rating

7.5/10Better

Monthly Price

$219

Medications

tirzepatide

Pros

✓Flat pricing that does not punish titration: $219/month for tirzepatide with "Same Price at Any Dose — No Tiered Price Hikes"
✓Everything needed to inject is included - syringes, needles and step-by-step instructions - which sounds small until you have to source them yourself
✓Free, discreet shipping direct to your door
✓A published phone number, 813-413-1000, and stated support hours of Monday to Friday 10am-5pm EST
✓Provider-led care with ongoing medical consultations included rather than charged per visit
✓Weight-loss claims are footnoted to the actual trial - SURMOUNT-1, 72 weeks - with the caveat that individual results vary and are not guaranteed
✓An established men's health clinic with adjacent testosterone, anti-aging and sexual-health services and in-house lab ordering

Cons

✗A three-month minimum purchase, so $219/month is really a $657 commitment before you know how you tolerate the medication
✗The medication is compounded, not FDA-approved
✗Support hours are narrow: Monday to Friday, 10am to 5pm EST only, with nothing at evenings or weekends
✗Marketing claims are large and unverifiable from the page: "Trusted by 350,000+ Men" and "4.9★ (2,000+ Reviews)" are presented without linking to the source of either figure
✗Tirzepatide only - no semaglutide option within the weight-loss line
✗Framed entirely around men, so it is not the right starting point if you are not one
✗No insurance billing, and HSA/FSA acceptance is not stated
✗The scrolling marquee of claims across the top of the page is closer to advertising than disclosure

Choose TRT Nation

Feature-by-feature comparison

Feature	MEDVi Quad	TRT Nation
Monthly Price	$114	$219
Rating	6.5/10	7.5/10
Medications	sildenafil, tadalafil, bremelanotide (PT-141), L-citrulline	tirzepatide
Insurance Accepted	No	No
Support Hours	24/7 medical support advertised	Monday to Friday, 10am-5pm EST
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free rush shipping included in the monthly price	Free, discreet shipping direct to your door
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	24/7 medical support advertised; follow-up cadence not published	Ongoing medical consultations and provider check-ins included
Money-back Guarantee	No charge if you do not qualify; no refund policy published for dispensed medication	None published
Cancellation Policy	Cancel anytime	Three-month minimum purchase on the tirzepatide programme

Which should you choose?

Choose MEDVi Quad if you:

→Want to save $105/month with a more affordable option
→Want more medication options to choose from
→Value: $114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked july 28, 2026)

Get started with MEDVi Quad

Choose TRT Nation if you:

→Prefer a higher-rated service (7.5/10 vs 6.5/10)
→Value: flat pricing that does not punish titration: $219/month for tirzepatide with "same price at any dose — no tiered price hikes"

Get started with TRT Nation

Website previews

MEDVi Quad

MEDVi Quad website

TRT Nation

TRT Nation website

Our recommendation

TRT Nation comes out ahead with a higher rating of 7.5/10.

Get started with TRT Nation

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