MEDVi Quad vs Winona
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
MEDVi Quad vs Winona: Overview
Choosing between MEDVi Quad and Winona for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
MEDVi Quad offers both semaglutide and tirzepatide at $114/month with a rating of 6.5/10. Winona also provides both semaglutide and tirzepatide at $89/month with a 8.4/10 rating.
With only a $25/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$25/mo
Rating Difference
1.9
Winner
Winona
Best For
Budget
MEDVi Quad
View full MEDVi Quad review →Rating
6.5/10
Monthly Price
$114
Medications
sildenafiltadalafilbremelanotide (PT-141)L-citrulline
Pros
- ✓$114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked July 28, 2026)
- ✓Cancel anytime, and the page states you are not charged if you do not qualify
- ✓All four active ingredients are named openly - PT-141 (bremelanotide), L-citrulline, sildenafil and tadalafil - rather than hidden behind a proprietary blend name
- ✓Sublingual delivery is a real advantage over tablets: it bypasses first-pass metabolism, so onset is faster and a heavy meal does not blunt absorption the way it can with oral sildenafil
- ✓Backed by a substantial independent review record - roughly 14,000 Trustpilot reviews at 4.4, with 99% of negative reviews answered
- ✓A published phone number, email address and physical address, which many competitors in this category omit entirely
Cons
- ✗'Peak rigidity guaranteed' appears directly in the product copy. No prescription medication can guarantee an outcome, and this is the most explicit outcome promise we have seen across every provider reviewed on this site
- ✗The formula stacks two PDE5 inhibitors - sildenafil and tadalafil - and then adds L-citrulline, a nitric oxide precursor. All three act on the same nitric oxide and cGMP pathway, so the blood-pressure-lowering effect compounds three ways rather than one
- ✗PT-141 adds a fourth agent that independently causes low blood pressure, nausea and flushing. Four actives, four routes to hypotension, and no discussion anywhere on the page of the combined risk
- ✗Bremelanotide's only FDA approval is as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Prescribing it to men in a compounded sublingual liquid is off-label and a different route of administration
- ✗The word FDA does not appear on the page at all. The product is compounded, and the page never states the consequence - that compounded preparations are not reviewed or approved by the FDA for safety, efficacy or quality
- ✗'The world's first 4-in-1 formula' and 'hospital-grade power' are unverifiable marketing superlatives attached to a prescription product
- ✗The advertised Trustpilot score covers MEDVi's business as a whole rather than this specific product
- ✗The published address is a suite at a Delaware registered-agent building, not a clinical facility
- ✗Anyone taking nitrates or riociguat must not use this product. The PT-141 component also interacts with 5-HT3 anti-emetics such as ondansetron, and stacking two PDE5 inhibitors makes the nitrate contraindication more dangerous, not less
Winona
View full Winona review →Rating
8.4/10Better
Monthly Price
$89Cheaper
Medications
bioidentical estradiolprogesteroneestriolDHEAsildenafilminoxidil
Pros
- ✓The full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked July 28, 2026)
- ✓Multiple delivery routes are offered - patch, body cream, vaginal cream, tablet and capsule - so treatment can be matched to preference rather than to whatever the company happens to stock
- ✓Winona owns its own 503A compounding pharmacies rather than outsourcing to a partner, which gives it direct control over formulation and consistency
- ✓Its pharmacy page explains the 503A/503B distinction correctly and states that 503A pharmacies are regulated by State Boards of Pharmacy, not the FDA - an accurate description that competitors routinely overstate
- ✓Roughly 8,000 Trustpilot reviews at 4.6, with 99% of negative reviews answered and a typical reply time under 24 hours
- ✓The rating advertised on site matches the rating on the public Trustpilot profile
- ✓The initial visit is free, so you can be assessed before paying for treatment
- ✓Editorial content carries numbered citations rather than unsourced assertions, and the site runs a public subreddit alongside a help centre and published phone number
- ✓HSA/FSA eligible, with a dedicated page explaining eligibility
- ✓Adjacent products are priced transparently too - DHEA from $27 per 3-month supply, sildenafil arousal cream at $79 per order, minoxidil hair serum at $150 per 3-month supply
Cons
- ✗Everything Winona dispenses is compounded in its own 503A pharmacies, which means it is not FDA-approved and has not been evaluated by the FDA for safety, efficacy or quality. The site explains 503A status clearly but does not foreground the 'not FDA-approved' consequence as plainly
- ✗Pharmaceutical products cannot be returned, per the terms - so once a prescription ships, you own it
- ✗The terms carry a mandatory arbitration clause on an individual basis with a class-action waiver, set out in capitals at the top of the document
- ✗Every headline price is a 'from' figure, so the actual monthly cost depends on the dose your clinician prescribes and is not knowable before the consultation
- ✗The hormone therapy explainer describes HRT as 'scientifically proven to be the safest, most effective treatment' for menopause symptoms. It is cited, but that is a strong framing for a therapy whose risk profile still depends heavily on age, time since menopause and personal history
- ✗Trustpilot notes Winona invites customers to review, which tends to lift scores relative to organic-only profiles, and that it may use AI-assisted replies
- ✗Systemic estrogen is not appropriate for everyone - women with a history of breast or endometrial cancer, unexplained vaginal bleeding, blood clots, stroke or liver disease should not start it without specialist input
- ✗Compounded hormone therapy in general lacks the long-term outcome data that exists for FDA-approved products, so the evidence cited for HRT as a class does not transfer automatically to these specific preparations
Feature-by-feature comparison
| Feature | MEDVi Quad | Winona |
|---|---|---|
| Monthly Price | $114 | $89 |
| Rating | 6.5/10 | 8.4/10 |
| Medications | sildenafil, tadalafil, bremelanotide (PT-141), L-citrulline | bioidentical estradiol, progesterone, estriol, DHEA, sildenafil, minoxidil |
| Insurance Accepted | No | No |
| Support Hours | 24/7 medical support advertised | Help centre and chat available; hours not published |
| Live Chat | No | Available |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free rush shipping included in the monthly price | Shipped to your door after clinician review; free shipping included |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | 24/7 medical support advertised; follow-up cadence not published | Ongoing clinician access through the patient portal; cadence not published |
| Money-back Guarantee | No charge if you do not qualify; no refund policy published for dispensed medication | None published; pharmaceutical products cannot be returned. A separate cancellation and refund policy governs subscriptions |
| Cancellation Policy | Cancel anytime | Subscriptions can be cancelled from your account; a separate cancellation policy governs when it takes effect |
Which should you choose?
Choose MEDVi Quad if you:
- →Value: $114/month, reduced from a stated $179, and the price is all-in: doctor consultation, free rush shipping and 24/7 medical support are included with no separate consultation fee (checked july 28, 2026)
Choose Winona if you:
- →Want to save $25/month with a more affordable option
- →Prefer a higher-rated service (8.4/10 vs 6.5/10)
- →Want more medication options to choose from
- →Value: the full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked july 28, 2026)
Website previews
MEDVi Quad
Winona
Our recommendation
Winona comes out ahead with a higher rating of 8.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with WinonaRelated comparisons
MEDVi Quad vs CoreAge Rx
$114
★ 6.5
vs
$99
★ 9.6
MEDVi Quad vs Zepbound
$114
★ 6.5
vs
$450
★ 9.3
MEDVi Quad vs Mounjaro
$114
★ 6.5
vs
$1080
★ 9.2
MEDVi Quad vs Wegovy Pill
$114
★ 6.5
vs
$149
★ 9.2
MEDVi Quad vs Foundayo
$114
★ 6.5
vs
$149
★ 9.2
MEDVi Quad vs Wegovy
$114
★ 6.5
vs
$349
★ 9.1
MEDVi Quad vs NovoCare Pharmacy
$114
★ 6.5
vs
$149
★ 9
MEDVi Quad vs Ozempic
$114
★ 6.5
vs
$349
★ 8.9
MEDVi Quad vs Form Health
$114
★ 6.5
vs
$299
★ 8.8
MEDVi Quad vs Henry Meds
$114
★ 6.5
vs
$179
★ 8.7
MEDVi Quad vs Sesame Care
$114
★ 6.5
vs
$59
★ 8.7
MEDVi Quad vs FuturHealth
$114
★ 6.5
vs
$225
★ 8.7
MEDVi Quad vs Circle Medical
$114
★ 6.5
vs
$35
★ 8.7
MEDVi Quad vs Ro
$114
★ 6.5
vs
$149
★ 8.6
MEDVi Quad vs Midi Health
$114
★ 6.5
vs
$164
★ 8.6
MEDVi Quad vs Noom Med
$114
★ 6.5
vs
$149
★ 8.6
MEDVi Quad vs Precision Telemed
$114
★ 6.5
vs
$150
★ 8.6
MEDVi Quad vs Hims
$114
★ 6.5
vs
$298
★ 8.5
MEDVi Quad vs Calibrate
$114
★ 6.5
vs
$199
★ 8.5
MEDVi Quad vs PlushCare
$114
★ 6.5
vs
$20
★ 8.5
Compare other providers
Compare GLP-1 Brands
vs