Midi Health vs Sesame Care
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Midi Health vs Sesame Care: Overview
Choosing between Midi Health and Sesame Care for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Midi Health offers both semaglutide and tirzepatide at $164/month with a rating of 8.6/10. Sesame Care also provides both semaglutide and tirzepatide at $59/month with a 8.7/10 rating.
The price difference of $105/month is significant - Sesame Care is the more budget-friendly option, while Midi Health positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$105/mo
Rating Difference
0.1
Winner
Sesame Care
Best For
Budget
Midi Health
View full Midi Health review →Rating
8.6/10
Monthly Price
$164
Medications
compounded GLP-1compounded GLP-1/GIPbrand-name GLP-1s
Pros
- ✓The GLP-1 pricing page is the most transparent we have seen anywhere in this category: a dose-by-dose table for four different products, with shipping and supplies included in every figure (checked July 28, 2026)
- ✓Compounded GLP-1 injectable runs $165.90 for the lowest doses, $270.90 in the mid range and $355.00 at the top; the dual-action GLP-1/GIP injectable runs $210.00 to $434.00, all for a 4-week supply
- ✓Sublingual options are offered as well, from $164.00 for GLP-1 and $209.00 for dual-action GLP-1/GIP, for people who will not inject
- ✓Its partner compounding pharmacies are 503B-accredited. 503B outsourcing facilities register with the FDA, are subject to current good manufacturing practice requirements and are FDA-inspected - a materially higher standard than the 503A pharmacies most competitors use
- ✓There is no membership fee. You pay for care and medication only
- ✓Visits are insurance-covered for qualifying patients, and HSA/FSA funds can be used for copays and services
- ✓Midi will also prescribe brand-name GLP-1s sent to a pharmacy of your choice, so you are not locked into compounded product if you would rather have the approved drug
- ✓The efficacy claim is the best-sourced in this category. Midi reports patients lost an average of 16 lbs after six or more months, and footnotes it to a retrospective analysis of 6,958 patients who completed two or more weight management visits between 1 May 2025 and 30 April 2026, while stating plainly that weight data were self-reported and results are not guaranteed
- ✓Care is genuinely whole-person for midlife women - perimenopause, menopause, weight, mood and memory, sexual wellness, hair and skin, sleep, and cancer survivorship - with lab orders and lifestyle support included where appropriate
- ✓Available in all 50 states
Cons
- ✗The compounded products are still not FDA-approved. 503B accreditation raises the manufacturing standard considerably but does not mean the FDA has reviewed these preparations for safety or efficacy
- ✗Midi never names the active drug anywhere in its pricing. Everything is labelled 'GLP-1' or 'GLP-1/GIP'. The dose ladders shown - 0.25 through 2.5 mg, and 2.5 through 15 mg - match the standard semaglutide and tirzepatide titrations exactly, but you should confirm with the clinician what you are actually being prescribed
- ✗Microdosing is offered from $34 a week for eligible patients. Microdosing is not an evidence-based protocol - the trials behind these drugs used full therapeutic doses, and the 16 lb outcome figure covers patients on 'a range of treatments', not microdosing specifically
- ✗Medicaid and Medi-Cal patients cannot be treated at all, even if they offer to pay cash
- ✗Medicare does not cover Midi, and beneficiaries cannot submit claims for visits, medications or associated services
- ✗Prices rise steeply as you titrate up. Injectable GLP-1 more than doubles from $165.90 to $355.00, and the dual-action sublingual runs from $209.00 to $460.00, so the entry price is not what you will pay long term
- ✗The 16 lb average comes from self-reported weights in a retrospective chart review with no control group - well documented, but not a controlled trial
- ✗GLP-1 medications are not suitable for anyone with a personal or family history of medullary thyroid carcinoma or MEN 2, or during pregnancy. Pancreatitis and gallbladder disease are recognised risks
Sesame Care
View full Sesame Care review →Rating
8.7/10Better
Monthly Price
$59Cheaper
Medications
semaglutidetirzepatideorforglipron
Pros
- ✓Publishes cash prices dose by dose, which no other provider on this site does. Zepbound KwikPen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
- ✓The same detail applies across the range: Wegovy pill $149/mo (1.5mg, 4mg) or $299 (9mg, 25mg); Wegovy pen $199 for the first two months for new patients then $349; Foundayo from $149 to $349 depending on dose (checked July 27, 2026)
- ✓Every medication offered is FDA-approved and branded - no compounded product is involved
- ✓Insurance is accepted, and with coverage medication can drop to as low as $25/mo
- ✓The care programme itself - video visits, dedicated provider, labs and messaging - starts at $59/mo
- ✓Efficacy milestones are properly sourced, citing a study of injectable semaglutide 2.4mg with the population spelled out (BMI 30+, or 27+ with a weight-related condition, non-diabetic) and paired with lifestyle change
- ✓A full refund is available if you cancel at least three hours before your first visit
- ✓The wider marketplace lets you compare individual providers on price, with appointments from $37
Cons
- ✗The $59/mo headline depends on a 12-month 'Success by Sesame' commitment, and the annual fee is explicitly non-refundable once paid - cancel in month two and you do not get the remaining ten months back
- ✗Medication costs are not included in the programme price, which Sesame states plainly but which means the real monthly outlay is the subscription plus the drug
- ✗Cash prices escalate steeply with dose. Zepbound more than doubles from $299 to $698 as you titrate to a maintenance dose, so the entry price is not the price you will end up paying
- ✗The Wegovy pen intro rate of $199 applies to new patients only and for two months, after which it is $349
- ✗Monthly subscribers are not refunded for months already paid, even if unused
- ✗Because pricing depends on insurance status, pharmacy and dose, there is no single figure you can plan around before signing up
- ✗This is a general healthcare marketplace, so the weight-loss programme sits alongside urgent care and prescription refills rather than being a dedicated speciality service
Feature-by-feature comparison
| Feature | Midi Health | Sesame Care |
|---|---|---|
| Monthly Price | $164 | $59 |
| Rating | 8.6/10 | 8.7/10 |
| Medications | compounded GLP-1, compounded GLP-1/GIP, brand-name GLP-1s | semaglutide, tirzepatide, orforglipron |
| Insurance Accepted | Yes | Yes |
| Support Hours | Not published | Not published |
| Live Chat | No | No |
| Free Shipping | Yes | No |
| Shipping Speed | Discreet shipping included in every quoted medication price | Filled at your pharmacy; not shipped by Sesame |
| Mobile App | No | Available |
| Dedicated Coach | Not included | Included |
| Follow-up Frequency | Continued care visits with the same clinician, covered by insurance for qualifying patients | Ongoing video visits, labs and messaging with a dedicated provider |
| Money-back Guarantee | None published | Full refund if you cancel at least 3 hours before your first visit; annual fees are non-refundable once paid |
| Cancellation Policy | No membership fee and no subscription lock-in; you pay for care and medication only | Self-cancel monthly or annual subscriptions any time, but past months and annual fees are not refunded |
Which should you choose?
Choose Midi Health if you:
- →Value: the glp-1 pricing page is the most transparent we have seen anywhere in this category: a dose-by-dose table for four different products, with shipping and supplies included in every figure (checked july 28, 2026)
Choose Sesame Care if you:
- →Want to save $105/month with a more affordable option
- →Prefer a higher-rated service (8.7/10 vs 8.6/10)
- →Want personalized coaching support included
- →Value: publishes cash prices dose by dose, which no other provider on this site does. zepbound kwikpen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
Website previews
Midi Health
Sesame Care
Our recommendation
Sesame Care comes out ahead with a higher rating of 8.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with Sesame CareRelated comparisons
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