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Ozempic vs Signos

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Ozempic vs Signos: Overview

Choosing between Ozempic and Signos for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Ozempic focuses on semaglutide at $349/month with a rating of 8.9/10. Signos offers continuous glucose monitoring at $127/month with a 7.8/10 rating.

The price difference of $222/month is significant - Signos is the more budget-friendly option, while Ozempic positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$222/mo

Rating Difference

1.1

Winner

Ozempic

Best For

Quality

Ozempic

View full Ozempic review →

Rating

8.9/10Better

Monthly Price

$349

Medications

semaglutide

Pros

✓FDA-approved for type 2 diabetes
✓Weekly injection
✓Effective for weight loss (~10-15%)
✓Widely available
✓Often covered by insurance for diabetes

Cons

✗Approved for diabetes, not weight loss
✗Requires prescription
✗GI side effects common
✗May be prescribed off-label for weight loss

Signos

View full Signos review →

Rating

7.8/10

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Feature-by-feature comparison

Feature	Ozempic	Signos
Monthly Price	$349	$127
Rating	8.9/10	7.8/10
Medications	semaglutide	continuous glucose monitoring
Insurance Accepted	Yes	No
Support Hours	Mon-Fri 8AM-8PM ET	In-app dietitian chat; hours not published
Live Chat	No	Available
Free Shipping	No	Yes
Shipping Speed	Varies by pharmacy	Free shipping; six-month plans ship in three-month bundles
Mobile App	No	Available
Dedicated Coach	Not included	Included
Follow-up Frequency	As prescribed by physician	Continuous glucose data with in-app dietitian support
Money-back Guarantee	Savings card available (as low as $25 for eligible patients)	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)
Cancellation Policy	Prescription-based, consult doctor	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused

Which should you choose?

Choose Ozempic if you:

→Prefer a higher-rated service (8.9/10 vs 7.8/10)
→Need insurance coverage for your treatment
→Value: fda-approved for type 2 diabetes

Get started with Ozempic

Choose Signos if you:

→Want to save $222/month with a more affordable option
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Website previews

Ozempic

Ozempic website

Signos

Signos website

Our recommendation

Ozempic comes out ahead with a higher rating of 8.9/10.

Get started with Ozempic

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