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Refills vs Enhance MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Refills vs Enhance MD: Overview

Choosing between Refills and Enhance MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Refills offers both semaglutide and tirzepatide at $150/month with a rating of 7.8/10. Enhance MD also provides both semaglutide and tirzepatide at $212/month with a 7.7/10 rating.

The price difference of $62/month is significant - Refills is the more budget-friendly option, while Enhance MD positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$62/mo

Rating Difference

0.1

Winner

Refills

Best For

Budget

Refills

View full Refills review →

Rating

7.8/10Better

Monthly Price

$150Cheaper

Medications

semaglutidetirzepatide

Pros

✓The largest verifiable review base of any provider in this batch: the Trustpilot profile for refills.com showed a 4-star TrustScore from roughly 1,244 reviews when we checked
✓No membership or app fees, stated as a headline promise: "Never Pay for Monthly Memberships or App Fees"
✓All dosages cost the same - "We don't charge you based on dosage changes" - which removes the titration price trap that catches most compounded GLP-1 patients
✓Both a GLP-1 (semaglutide-class) and a GIP + GLP-1 (tirzepatide-class) injectable are offered
✓A published phone number, 888-458-5061, and support@refills.com, with 24/7 health-concierge support advertised
✓Free and discreet shipping on every order
✓Unusually candid disclaimers: it states plainly that compounded drug products are not approved or evaluated by the FDA, and that Refills Health is not a medical services provider but a technology platform
✓It names its clinical partners - Beluga Health, Bask Health and Wasef Health - rather than referring vaguely to "our providers"
✓Certificates of Analysis are available on request for any batch
✓LegitScript certification is displayed

Cons

✗Pricing is quoted per day, not per month. "GLP-1s from $5/day" reads as cheap but is $150 a month, and the site never states a monthly figure
✗Refills is a technology platform, not a medical provider. It does not manufacture or dispense medication and does not employ the clinicians who prescribe
✗All prescription sales are final. State and federal rules do not allow returns of dispensed prescription medication, and once your card is charged and the package is handed to the carrier there is no refund
✗Returns are only accepted on unopened, non-prescription items within 30 days, and you pay the return shipping
✗It does not ship refrigerated products, which the returns page presents as a benefit ("your product will not be affected by increased transit time") but which is worth understanding before you order
✗The medication is compounded, so it has not been evaluated by the FDA for safety, quality or efficacy
✗Available across the US but explicitly not in the District of Columbia
✗Before/after testimonials headline losses of 40 to 120 pounds. The disclaimer that results are not typical is present but far less prominent than the numbers

Enhance MD

View full Enhance MD review →

Rating

7.7/10

Monthly Price

$212

Medications

semaglutidetirzepatide

Pros

✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
✓Product images are labelled 'Not actual vial - For marketing purposes only'
✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
✓Medication ships quarterly, so there are fewer delivery events to manage
✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
✗No published customer phone number or support hours
✗No BBB profile or independent complaint record to check
✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate

Choose Enhance MD

Feature-by-feature comparison

Feature	Refills	Enhance MD
Monthly Price	$150	$212
Rating	7.8/10	7.7/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Company advertises free 24/7 support from a health concierge	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; non-refrigerated products shipped via USPS, FedEx or UPS	Medication shipped every 12 weeks
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Providers reassess and adjust dose, titration pace or treatment on request	Ongoing provider care and support included
Money-back Guarantee	None. All prescription sales are final once dispatched	Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding
Cancellation Policy	You can log in and cancel your subscription, change your address or change your payment method any time before the order is sent to the pharmacy	Plans run monthly or in 3+ month blocks; no separate cancellation policy published

Which should you choose?

Choose Refills if you:

→Want to save $62/month with a more affordable option
→Prefer a higher-rated service (7.8/10 vs 7.7/10)
→Value: the largest verifiable review base of any provider in this batch: the trustpilot profile for refills.com showed a 4-star trustscore from roughly 1,244 reviews when we checked

Get started with Refills

Choose Enhance MD if you:

→Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Get started with Enhance MD

Website previews

Refills

Refills website

Enhance MD

Enhance MD website

Our recommendation

Refills comes out ahead with a higher rating of 7.8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Refills

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