Refills vs RxSpan MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Refills vs RxSpan MD: Overview

Choosing between Refills and RxSpan MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Refills offers both semaglutide and tirzepatide at $150/month with a rating of 7.8/10. RxSpan MD also provides both semaglutide and tirzepatide at $249/month with a 7.6/10 rating.

The price difference of $99/month is significant - Refills is the more budget-friendly option, while RxSpan MD positions itself as a premium service.

VERIFIED

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

At a glance

Price Difference
$99/mo
Rating Difference
0.2
Winner
Refills
Best For
Budget

Refills

View full Refills review →
Rating
7.8/10Better
Monthly Price
$150Cheaper
Medications
semaglutidetirzepatide

Pros

  • The largest verifiable review base of any provider in this batch: the Trustpilot profile for refills.com showed a 4-star TrustScore from roughly 1,244 reviews when we checked
  • No membership or app fees, stated as a headline promise: "Never Pay for Monthly Memberships or App Fees"
  • All dosages cost the same - "We don't charge you based on dosage changes" - which removes the titration price trap that catches most compounded GLP-1 patients
  • Both a GLP-1 (semaglutide-class) and a GIP + GLP-1 (tirzepatide-class) injectable are offered
  • A published phone number, 888-458-5061, and support@refills.com, with 24/7 health-concierge support advertised
  • Free and discreet shipping on every order
  • Unusually candid disclaimers: it states plainly that compounded drug products are not approved or evaluated by the FDA, and that Refills Health is not a medical services provider but a technology platform
  • It names its clinical partners - Beluga Health, Bask Health and Wasef Health - rather than referring vaguely to "our providers"
  • Certificates of Analysis are available on request for any batch
  • LegitScript certification is displayed

Cons

  • Pricing is quoted per day, not per month. "GLP-1s from $5/day" reads as cheap but is $150 a month, and the site never states a monthly figure
  • Refills is a technology platform, not a medical provider. It does not manufacture or dispense medication and does not employ the clinicians who prescribe
  • All prescription sales are final. State and federal rules do not allow returns of dispensed prescription medication, and once your card is charged and the package is handed to the carrier there is no refund
  • Returns are only accepted on unopened, non-prescription items within 30 days, and you pay the return shipping
  • It does not ship refrigerated products, which the returns page presents as a benefit ("your product will not be affected by increased transit time") but which is worth understanding before you order
  • The medication is compounded, so it has not been evaluated by the FDA for safety, quality or efficacy
  • Available across the US but explicitly not in the District of Columbia
  • Before/after testimonials headline losses of 40 to 120 pounds. The disclaimer that results are not typical is present but far less prominent than the numbers
Choose Refills

RxSpan MD

View full RxSpan MD review →
Rating
7.6/10
Monthly Price
$249
Medications
semaglutidetirzepatide

Pros

  • A full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked July 27, 2026)
  • Brand-name options are offered and priced openly too - Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069
  • The plan ladder is shown with each rate: $249/mo monthly, $219/mo on 3 months, $199/mo on 6 months and $194/mo on 12 months
  • The price is stated to include the consult, medication, supplies, shipping and support, with no separate membership fee
  • Oral capsule versions of both semaglutide and tirzepatide are available for people who do not want injections
  • Plans can be cancelled or changed at any time
  • The site states plainly that 'Prescription is not guaranteed' rather than implying approval is automatic
  • A named, credentialled physician is associated with the service rather than an anonymous 'medical team'

Cons

  • Every headline price is labelled 'For the first month'. What you pay from month two is not shown anywhere on the product screen, so the ongoing cost is unknown until you are further into the funnel
  • You pay at checkout before a provider reviews your case - the site confirms 'After checkout, a provider will review your information to determine if treatment is right for you' - so your money goes first and eligibility is decided afterwards
  • There is no independent review signal at all: no Trustpilot profile, no BBB file, and no rating displayed on site
  • Brand-name pricing is far above the manufacturers' own direct-pay programmes - $1,349 for Wegovy and $1,069 for Zepbound against considerably cheaper NovoCare and LillyDirect routes
  • No customer phone number is published; the only contact is an email address
  • The supervising physician's board certification is in plastic surgery, not obesity medicine, endocrinology or internal medicine
  • The banner copy - 'No Hidden Fees', 'Free, Expedited Delivery', 'Doctor-led Plans & Coaching' - is word-for-word identical to TrimRx's, indicating a shared white-label funnel rather than an independently built service
  • Product prices only render once JavaScript loads; with scripts blocked the weight-loss category reads 'No products found for Weight Loss'
Choose RxSpan MD

Feature-by-feature comparison

FeatureRefillsRxSpan MD
Monthly Price$150$249
Rating7.8/107.6/10
Medicationssemaglutide, tirzepatidesemaglutide, tirzepatide
Insurance AcceptedNoNo
Support HoursCompany advertises free 24/7 support from a health conciergeNot published
Live ChatNoNo
Free ShippingYesYes
Shipping SpeedFree shipping; non-refrigerated products shipped via USPS, FedEx or UPSFree expedited delivery claimed; timeframe not published
Mobile AppNoNo
Dedicated CoachNot includedIncluded
Follow-up FrequencyProviders reassess and adjust dose, titration pace or treatment on requestDoctor-led plans and coaching advertised; frequency not published
Money-back GuaranteeNone. All prescription sales are final once dispatchedNone published; you are charged at checkout before a provider decides whether to prescribe
Cancellation PolicyYou can log in and cancel your subscription, change your address or change your payment method any time before the order is sent to the pharmacyCancel or change plans at any time

Which should you choose?

Choose Refills if you:

  • Want to save $99/month with a more affordable option
  • Prefer a higher-rated service (7.8/10 vs 7.6/10)
  • Value: the largest verifiable review base of any provider in this batch: the trustpilot profile for refills.com showed a 4-star trustscore from roughly 1,244 reviews when we checked

Choose RxSpan MD if you:

  • Want personalized coaching support included
  • Value: a full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked july 27, 2026)

Website previews

Refills

Refills website

RxSpan MD

RxSpan MD website

Our recommendation

Refills comes out ahead with a higher rating of 7.8/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with Refills

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