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Refills vs SynergyRX

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Refills vs SynergyRX: Overview

Choosing between Refills and SynergyRX for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Refills offers both semaglutide and tirzepatide at $150/month with a rating of 7.8/10. SynergyRX also provides both semaglutide and tirzepatide at $199/month with a 7.4/10 rating.

With only a $49/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$49/mo

Rating Difference

0.4

Winner

Refills

Best For

Budget

Refills

View full Refills review →

Rating

7.8/10Better

Monthly Price

$150Cheaper

Medications

semaglutidetirzepatide

Pros

✓The largest verifiable review base of any provider in this batch: the Trustpilot profile for refills.com showed a 4-star TrustScore from roughly 1,244 reviews when we checked
✓No membership or app fees, stated as a headline promise: "Never Pay for Monthly Memberships or App Fees"
✓All dosages cost the same - "We don't charge you based on dosage changes" - which removes the titration price trap that catches most compounded GLP-1 patients
✓Both a GLP-1 (semaglutide-class) and a GIP + GLP-1 (tirzepatide-class) injectable are offered
✓A published phone number, 888-458-5061, and support@refills.com, with 24/7 health-concierge support advertised
✓Free and discreet shipping on every order
✓Unusually candid disclaimers: it states plainly that compounded drug products are not approved or evaluated by the FDA, and that Refills Health is not a medical services provider but a technology platform
✓It names its clinical partners - Beluga Health, Bask Health and Wasef Health - rather than referring vaguely to "our providers"
✓Certificates of Analysis are available on request for any batch
✓LegitScript certification is displayed

Cons

✗Pricing is quoted per day, not per month. "GLP-1s from $5/day" reads as cheap but is $150 a month, and the site never states a monthly figure
✗Refills is a technology platform, not a medical provider. It does not manufacture or dispense medication and does not employ the clinicians who prescribe
✗All prescription sales are final. State and federal rules do not allow returns of dispensed prescription medication, and once your card is charged and the package is handed to the carrier there is no refund
✗Returns are only accepted on unopened, non-prescription items within 30 days, and you pay the return shipping
✗It does not ship refrigerated products, which the returns page presents as a benefit ("your product will not be affected by increased transit time") but which is worth understanding before you order
✗The medication is compounded, so it has not been evaluated by the FDA for safety, quality or efficacy
✗Available across the US but explicitly not in the District of Columbia
✗Before/after testimonials headline losses of 40 to 120 pounds. The disclaimer that results are not typical is present but far less prominent than the numbers

SynergyRX

View full SynergyRX review →

Rating

7.4/10

Monthly Price

$199

Medications

semaglutidetirzepatide

Pros

✓A complete GLP-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked July 27, 2026)
✓Brand-name options are priced too, and Ozempic at $499 is notably cheaper here than Wegovy or Mounjaro at $947
✓Oral dissolving tablet versions of both molecules are available for people who will not inject
✓A $100 welcome credit is applied automatically at checkout with no code to hunt for
✓FSA and HSA eligible, with free shipping
✓The FAQ explicitly raises the compounded-versus-brand-name question rather than avoiding it
✓Longevity, hair, skin and sexual health lines are available from the same provider

Cons

✗On a weight-loss landing page, the product carousel opens on the longevity tab. Every GLP-1 and its price is hidden behind a 'WEIGHT LOSS' tab you have to find and click - a visitor who does not spot it sees only NAD+, sermorelin, glutathione, B12 and PT-141
✗There is no public review footprint at all - no Trustpilot profile, no BBB file - against a claim of 50,000+ patients
✗The oral tablets cost more than the injections ($299 against $199 for semaglutide), the reverse of how most competitors price them, with no explanation given
✗The call-to-action button reads 'SEE IF I'M ELLIGIBLE' - misspelled, and repeated twice on the page
✗The headline - 'The Proven Way to lose 15% of your body weight fast! Lose 1-2lbs per week' - is word-for-word the copy used by TrimRx and Embody, indicating a shared white-label funnel rather than an independently written site
✗The testimonial block under a weight-loss heading mixes weight-loss quotes with an NAD+ energy testimonial, and the same three quotes repeat on a loop
✗No refund or cancellation policy could be found anywhere on the site
✗No published phone number, support email or support hours

Choose SynergyRX

Feature-by-feature comparison

Feature	Refills	SynergyRX
Monthly Price	$150	$199
Rating	7.8/10	7.4/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Company advertises free 24/7 support from a health concierge	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; non-refrigerated products shipped via USPS, FedEx or UPS	Fast, free shipping claimed
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Providers reassess and adjust dose, titration pace or treatment on request	Not published
Money-back Guarantee	None. All prescription sales are final once dispatched	None published
Cancellation Policy	You can log in and cancel your subscription, change your address or change your payment method any time before the order is sent to the pharmacy	Not published

Which should you choose?

Choose Refills if you:

→Want to save $49/month with a more affordable option
→Prefer a higher-rated service (7.8/10 vs 7.4/10)
→Value: the largest verifiable review base of any provider in this batch: the trustpilot profile for refills.com showed a 4-star trustscore from roughly 1,244 reviews when we checked

Get started with Refills

Choose SynergyRX if you:

→Value: a complete glp-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked july 27, 2026)

Get started with SynergyRX

Website previews

Refills

Refills website

SynergyRX

SynergyRX website

Our recommendation

Refills comes out ahead with a higher rating of 7.8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Refills

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