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RNK Health vs Signos

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

RNK Health vs Signos: Overview

Choosing between RNK Health and Signos for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

RNK Health offers both semaglutide and tirzepatide at $197/month with a rating of 7.7/10. Signos offers continuous glucose monitoring at $127/month with a 7.8/10 rating.

The price difference of $70/month is significant - Signos is the more budget-friendly option, while RNK Health positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$70/mo

Rating Difference

0.1

Winner

Signos

Best For

Budget

RNK Health

View full RNK Health review →

Rating

7.7/10

Monthly Price

$197

Medications

semaglutidetirzepatide

Pros

✓Per-product prices are listed openly on the homepage rather than hidden behind a quiz: semaglutide from $197/mo, tirzepatide from $297/mo, NAD+ from $129/mo, sermorelin from $129/mo, B12-MIC from $97/mo (checked July 27, 2026)
✓Cancel or pause at any time with no long-term commitment, managed from your own account rather than by emailing support
✓Publishes both the dispensing pharmacy's location and the medical provider's address, which is unusually specific for this category
✓1-on-1 calls with US doctors are part of the programme, not an upsell
✓A satisfaction guarantee is advertised alongside progress tracking and built-in guidance
✓Trustpilot rating of 4.1 across 454 reviews gives at least a moderate independent signal
✓Wide catalogue if you want more than weight care - NAD+ in three delivery formats, sermorelin, enclomiphene and an 80-biomarker DNA panel

Cons

✗The affiliate link for this offer lands on RNK's NAD+ funnel, not its GLP-1 pages, so anyone following the link for weight loss arrives at a longevity product and has to navigate away
✗'Full pricing details are shown during checkout' - so the advertised 'from' prices are a floor, and what you actually pay is not visible until you are committing
✗We could not find an explicit 'not FDA-approved' disclosure for the compounded medications. Nearly every competitor states this plainly; RNK describes its products only as 'USA Compounded: Lab-tested, high-purity'
✗GLP-1 pricing is at the higher end - $197 for semaglutide and $297 for tirzepatide, where several rivals advertise under $150
✗The NAD+ landing page promises you will 'LOOK, FEEL & PERFORM 10 YEARS YOUNGER' with 'the most powerful NAD+ protocol on the market' - claims with no cited evidence
✗The 'satisfaction guarantee' and 'Risk FREE' language is used without published terms defining what either actually entitles you to
✗No BBB profile or complaint history to check
✗As with all compounded GLP-1s, no efficacy data specific to RNK's own patients is published

Choose RNK Health

Signos

View full Signos review →

Rating

7.8/10Better

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Feature-by-feature comparison

Feature	RNK Health	Signos
Monthly Price	$197	$127
Rating	7.7/10	7.8/10
Medications	semaglutide, tirzepatide	continuous glucose monitoring
Insurance Accepted	No	No
Support Hours	Not published	In-app dietitian chat; hours not published
Live Chat	No	Available
Free Shipping	Yes	Yes
Shipping Speed	Not published	Free shipping; six-month plans ship in three-month bundles
Mobile App	No	Available
Dedicated Coach	Not included	Included
Follow-up Frequency	1-on-1 calls with US doctors plus progress tracking	Continuous glucose data with in-app dietitian support
Money-back Guarantee	A satisfaction guarantee is advertised, but we found no published terms defining it	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)
Cancellation Policy	Cancel or pause any time from your account, with no long-term commitment	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused

Which should you choose?

Choose RNK Health if you:

→Want more medication options to choose from
→Value: per-product prices are listed openly on the homepage rather than hidden behind a quiz: semaglutide from $197/mo, tirzepatide from $297/mo, nad+ from $129/mo, sermorelin from $129/mo, b12-mic from $97/mo (checked july 27, 2026)

Get started with RNK Health

Choose Signos if you:

→Want to save $70/month with a more affordable option
→Prefer a higher-rated service (7.8/10 vs 7.7/10)
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Website previews

RNK Health

RNK Health website

Signos

Signos website

Our recommendation

Signos comes out ahead with a higher rating of 7.8/10.

Get started with Signos

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