Ro vs Enhance MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Ro vs Enhance MD: Overview

Choosing between Ro and Enhance MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Ro offers both semaglutide and tirzepatide at $149/month with a rating of 8.6/10. Enhance MD also provides both semaglutide and tirzepatide at $212/month with a 7.7/10 rating.

The price difference of $63/month is significant - Ro is the more budget-friendly option, while Enhance MD positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$63/mo

Rating Difference

0.9

Winner

Ro

Best For

Budget

Ro

View full Ro review →

Rating

8.6/10Better

Monthly Price

$149Cheaper

Medications

semaglutidetirzepatide

Pros

✓Prescribes FDA-approved, brand-name GLP-1s - Zepbound, Wegovy pen and pill, Ozempic, Saxenda and the new Foundayo pill - rather than compounded copies
✓Real insurance support: a dedicated team handles prior authorizations and appeals, and there is a free GLP-1 insurance checker you can run before paying anything
✓Publishes exact cash-pay prices for the Zepbound KwikPen: $299/mo at 2.5 mg, $399/mo at 5 mg and $449/mo at 7.5-15 mg with the manufacturer offer (checked July 26, 2026)
✓Membership is $39 for the first month, and as low as $74/mo if you prepay for a year
✓Long-established: trading since 2017, BBB accredited since 2018, and one of the largest telehealth platforms in the US
✓Prescriptions are typically filled and shipped within 1-4 days
✓Cash-pay Zepbound single-dose vials are available if you want to skip the insurance process entirely
✓Ongoing provider messaging, check-ins and progress tracking are included in the membership fee

Cons

✗The membership fee does not include your medication. At $149/mo month-to-month plus $449/mo for a maintenance dose of Zepbound, the realistic all-in cost is roughly $520-600 a month
✗The discounted $449 refill price depends on completing a check-in within 45 days of your last delivery. Miss that window and the price jumps to $499 for 7.5 mg, or $699 for the 10, 12.5 and 15 mg doses
✗All sales are final. Ro states it cannot issue refunds or accept returns on prescription products, except where it has made an error filling your prescription
✗The headline $74/mo membership rate requires prepaying a full year upfront
✗BBB lists 619 complaints, and Trustpilot sits at 3.8 from 4,796 reviews, with cancellation and billing the dominant negative themes
✗No customer phone number or support email is published on the site; support runs through your account
✗Because the medication price depends on your insurance, what you will actually pay each month cannot be known until after you have signed up and been assessed
✗The homepage claim 'Lose 20% body weight on average with Zepbound' comes from the manufacturer's trial of the branded drug, not from Ro's own patients

Choose Ro

Enhance MD

View full Enhance MD review →

Rating

7.7/10

Monthly Price

$212

Medications

semaglutidetirzepatide

Pros

✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
✓Product images are labelled 'Not actual vial - For marketing purposes only'
✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
✓Medication ships quarterly, so there are fewer delivery events to manage
✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
✗No published customer phone number or support hours
✗No BBB profile or independent complaint record to check
✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate

Choose Enhance MD

Feature-by-feature comparison

Feature	Ro	Enhance MD
Monthly Price	$149	$212
Rating	8.6/10	7.7/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	Yes	No
Support Hours	On-demand provider messaging (hours not published)	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Typically filled and shipped within 1-4 days	Medication shipped every 12 weeks
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Ongoing check-ins plus on-demand provider messaging	Ongoing provider care and support included
Money-back Guarantee	None - Ro states all sales of prescription products are final, except where it filled your prescription in error	Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding
Cancellation Policy	Cancel the membership before your next billing date; charges already processed are not refunded	Plans run monthly or in 3+ month blocks; no separate cancellation policy published

Which should you choose?

Choose Ro if you:

→Want to save $63/month with a more affordable option
→Prefer a higher-rated service (8.6/10 vs 7.7/10)
→Need insurance coverage for your treatment
→Want personalized coaching support included
→Value: prescribes fda-approved, brand-name glp-1s - zepbound, wegovy pen and pill, ozempic, saxenda and the new foundayo pill - rather than compounded copies

Get started with Ro

Choose Enhance MD if you:

→Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Get started with Enhance MD

Website previews

Ro

Enhance MD

Our recommendation

Ro comes out ahead with a higher rating of 8.6/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Ro

Ro vs Enhance MD

Ro vs Enhance MD: Overview

Our recommended brand

At a glance

Ro

Pros

Cons

Enhance MD

Pros

Cons

Feature-by-feature comparison

Which should you choose?

Choose Ro if you:

Choose Enhance MD if you:

Website previews

Ro

Enhance MD

Our recommendation

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