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RxSpan MD vs Sesame Care

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

RxSpan MD vs Sesame Care: Overview

Choosing between RxSpan MD and Sesame Care for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

RxSpan MD offers both semaglutide and tirzepatide at $249/month with a rating of 7.6/10. Sesame Care also provides both semaglutide and tirzepatide at $59/month with a 8.7/10 rating.

The price difference of $190/month is significant - Sesame Care is the more budget-friendly option, while RxSpan MD positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$190/mo

Rating Difference

1.1

Winner

Sesame Care

Best For

Budget

RxSpan MD

View full RxSpan MD review →

Rating

7.6/10

Monthly Price

$249

Medications

semaglutidetirzepatide

Pros

✓A full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked July 27, 2026)
✓Brand-name options are offered and priced openly too - Ozempic $1,299, Wegovy $1,349 and Zepbound $1,069
✓The plan ladder is shown with each rate: $249/mo monthly, $219/mo on 3 months, $199/mo on 6 months and $194/mo on 12 months
✓The price is stated to include the consult, medication, supplies, shipping and support, with no separate membership fee
✓Oral capsule versions of both semaglutide and tirzepatide are available for people who do not want injections
✓Plans can be cancelled or changed at any time
✓The site states plainly that 'Prescription is not guaranteed' rather than implying approval is automatic
✓A named, credentialled physician is associated with the service rather than an anonymous 'medical team'

Cons

✗Every headline price is labelled 'For the first month'. What you pay from month two is not shown anywhere on the product screen, so the ongoing cost is unknown until you are further into the funnel
✗You pay at checkout before a provider reviews your case - the site confirms 'After checkout, a provider will review your information to determine if treatment is right for you' - so your money goes first and eligibility is decided afterwards
✗There is no independent review signal at all: no Trustpilot profile, no BBB file, and no rating displayed on site
✗Brand-name pricing is far above the manufacturers' own direct-pay programmes - $1,349 for Wegovy and $1,069 for Zepbound against considerably cheaper NovoCare and LillyDirect routes
✗No customer phone number is published; the only contact is an email address
✗The supervising physician's board certification is in plastic surgery, not obesity medicine, endocrinology or internal medicine
✗The banner copy - 'No Hidden Fees', 'Free, Expedited Delivery', 'Doctor-led Plans & Coaching' - is word-for-word identical to TrimRx's, indicating a shared white-label funnel rather than an independently built service
✗Product prices only render once JavaScript loads; with scripts blocked the weight-loss category reads 'No products found for Weight Loss'

Choose RxSpan MD

Sesame Care

View full Sesame Care review →

Rating

8.7/10Better

Monthly Price

$59Cheaper

Medications

semaglutidetirzepatideorforglipron

Pros

✓Publishes cash prices dose by dose, which no other provider on this site does. Zepbound KwikPen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
✓The same detail applies across the range: Wegovy pill $149/mo (1.5mg, 4mg) or $299 (9mg, 25mg); Wegovy pen $199 for the first two months for new patients then $349; Foundayo from $149 to $349 depending on dose (checked July 27, 2026)
✓Every medication offered is FDA-approved and branded - no compounded product is involved
✓Insurance is accepted, and with coverage medication can drop to as low as $25/mo
✓The care programme itself - video visits, dedicated provider, labs and messaging - starts at $59/mo
✓Efficacy milestones are properly sourced, citing a study of injectable semaglutide 2.4mg with the population spelled out (BMI 30+, or 27+ with a weight-related condition, non-diabetic) and paired with lifestyle change
✓A full refund is available if you cancel at least three hours before your first visit
✓The wider marketplace lets you compare individual providers on price, with appointments from $37

Cons

✗The $59/mo headline depends on a 12-month 'Success by Sesame' commitment, and the annual fee is explicitly non-refundable once paid - cancel in month two and you do not get the remaining ten months back
✗Medication costs are not included in the programme price, which Sesame states plainly but which means the real monthly outlay is the subscription plus the drug
✗Cash prices escalate steeply with dose. Zepbound more than doubles from $299 to $698 as you titrate to a maintenance dose, so the entry price is not the price you will end up paying
✗The Wegovy pen intro rate of $199 applies to new patients only and for two months, after which it is $349
✗Monthly subscribers are not refunded for months already paid, even if unused
✗Because pricing depends on insurance status, pharmacy and dose, there is no single figure you can plan around before signing up
✗This is a general healthcare marketplace, so the weight-loss programme sits alongside urgent care and prescription refills rather than being a dedicated speciality service

Choose Sesame Care

Feature-by-feature comparison

Feature	RxSpan MD	Sesame Care
Monthly Price	$249	$59
Rating	7.6/10	8.7/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide, orforglipron
Insurance Accepted	No	Yes
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	No
Shipping Speed	Free expedited delivery claimed; timeframe not published	Filled at your pharmacy; not shipped by Sesame
Mobile App	No	Available
Dedicated Coach	Included	Included
Follow-up Frequency	Doctor-led plans and coaching advertised; frequency not published	Ongoing video visits, labs and messaging with a dedicated provider
Money-back Guarantee	None published; you are charged at checkout before a provider decides whether to prescribe	Full refund if you cancel at least 3 hours before your first visit; annual fees are non-refundable once paid
Cancellation Policy	Cancel or change plans at any time	Self-cancel monthly or annual subscriptions any time, but past months and annual fees are not refunded

Which should you choose?

Choose RxSpan MD if you:

→Value: a full product price list is published rather than a single teaser figure: semaglutide injection $249, tirzepatide injection $329, semaglutide capsules $249 and tirzepatide capsules $349 for the first month (checked july 27, 2026)

Get started with RxSpan MD

Choose Sesame Care if you:

→Want to save $190/month with a more affordable option
→Prefer a higher-rated service (8.7/10 vs 7.6/10)
→Want more medication options to choose from
→Need insurance coverage for your treatment
→Value: publishes cash prices dose by dose, which no other provider on this site does. zepbound kwikpen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start

Get started with Sesame Care

Website previews

RxSpan MD

RxSpan MD website

Sesame Care

Sesame Care website

Our recommendation

Sesame Care comes out ahead with a higher rating of 8.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Sesame Care

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