Sequence vs Zepbound

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Sequence vs Zepbound: Overview

Choosing between Sequence and Zepbound for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

Sequence offers both semaglutide and tirzepatide at $279/month with a rating of 9.2/10. Zepbound offers tirzepatide at $450/month with a 9.3/10 rating.

The price difference of $171/month is significant - Sequence is the more budget-friendly option, while Zepbound positions itself as a premium service.

VERIFIED

Our recommended brand

After reviewing all 78 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

At a glance

Price Difference
$171/mo
Rating Difference
0.1
Winner
Zepbound
Best For
Quality

Sequence

View full Sequence review →
Rating
9.2/10
Monthly Price
$279Cheaper
Medications
semaglutidetirzepatide

Pros

  • Top-tier medical team
  • Comprehensive care
  • Both GLP-1 options
  • Excellent results
  • White-glove service

Cons

  • Premium pricing
  • Not available in all states
  • Waitlist in some areas
Choose Sequence

Zepbound

View full Zepbound review →
Rating
9.3/10Better
Monthly Price
$450
Medications
tirzepatide

Pros

  • FDA-approved for chronic weight management
  • Weekly injection
  • Superior weight loss results (~21% average)
  • Same active ingredient as Mounjaro
  • Dual GIP/GLP-1 receptor agonist

Cons

  • Requires prescription and medical supervision
  • Can cause GI side effects
  • High cost without insurance coverage
  • Not available in all pharmacies
Choose Zepbound

Feature-by-feature comparison

FeatureSequenceZepbound
Monthly Price$279$450
Rating9.2/109.3/10
Medicationssemaglutide, tirzepatidetirzepatide
Insurance AcceptedYesYes
Support Hours24/7Mon-Fri 8AM-8PM ET
Live ChatAvailableNo
Free ShippingYesNo
Shipping Speed1-3 days expressVaries by pharmacy
Mobile AppAvailableNo
Dedicated CoachIncludedNot included
Follow-up FrequencyWeekly for first month, then bi-weeklyAs prescribed by physician
Money-back Guarantee90-day satisfaction guaranteeSavings card available for eligible patients
Cancellation PolicyCancel anytime, prorated refundPrescription-based, consult doctor

Which should you choose?

Choose Sequence if you:

  • Want to save $171/month with a more affordable option
  • Want more medication options to choose from
  • Want personalized coaching support included
  • Need 24/7 customer support availability
  • Value: top-tier medical team

Choose Zepbound if you:

  • Prefer a higher-rated service (9.3/10 vs 9.2/10)
  • Value: fda-approved for chronic weight management

Website previews

Sequence

Sequence website

Zepbound

Zepbound website

Our recommendation

Zepbound comes out ahead with a higher rating of 9.3/10.
Get started with Zepbound

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