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Sesame Care vs Zepbound

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Sesame Care vs Zepbound: Overview

Choosing between Sesame Care and Zepbound for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

Sesame Care offers both semaglutide and tirzepatide at $59/month with a rating of 8.7/10. Zepbound offers tirzepatide at $450/month with a 9.3/10 rating.

The price difference of $391/month is significant - Sesame Care is the more budget-friendly option, while Zepbound positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$391/mo

Rating Difference

0.6

Winner

Zepbound

Best For

Quality

Sesame Care

View full Sesame Care review →

Rating

8.7/10

Monthly Price

$59Cheaper

Medications

semaglutidetirzepatideorforglipron

Pros

✓Publishes cash prices dose by dose, which no other provider on this site does. Zepbound KwikPen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
✓The same detail applies across the range: Wegovy pill $149/mo (1.5mg, 4mg) or $299 (9mg, 25mg); Wegovy pen $199 for the first two months for new patients then $349; Foundayo from $149 to $349 depending on dose (checked July 27, 2026)
✓Every medication offered is FDA-approved and branded - no compounded product is involved
✓Insurance is accepted, and with coverage medication can drop to as low as $25/mo
✓The care programme itself - video visits, dedicated provider, labs and messaging - starts at $59/mo
✓Efficacy milestones are properly sourced, citing a study of injectable semaglutide 2.4mg with the population spelled out (BMI 30+, or 27+ with a weight-related condition, non-diabetic) and paired with lifestyle change
✓A full refund is available if you cancel at least three hours before your first visit
✓The wider marketplace lets you compare individual providers on price, with appointments from $37

Cons

✗The $59/mo headline depends on a 12-month 'Success by Sesame' commitment, and the annual fee is explicitly non-refundable once paid - cancel in month two and you do not get the remaining ten months back
✗Medication costs are not included in the programme price, which Sesame states plainly but which means the real monthly outlay is the subscription plus the drug
✗Cash prices escalate steeply with dose. Zepbound more than doubles from $299 to $698 as you titrate to a maintenance dose, so the entry price is not the price you will end up paying
✗The Wegovy pen intro rate of $199 applies to new patients only and for two months, after which it is $349
✗Monthly subscribers are not refunded for months already paid, even if unused
✗Because pricing depends on insurance status, pharmacy and dose, there is no single figure you can plan around before signing up
✗This is a general healthcare marketplace, so the weight-loss programme sits alongside urgent care and prescription refills rather than being a dedicated speciality service

Choose Sesame Care

Zepbound

View full Zepbound review →

Rating

9.3/10Better

Monthly Price

$450

Medications

tirzepatide

Pros

✓FDA-approved for chronic weight management
✓Weekly injection
✓Superior weight loss results (~21% average)
✓Same active ingredient as Mounjaro
✓Dual GIP/GLP-1 receptor agonist

Cons

✗Requires prescription and medical supervision
✗Can cause GI side effects
✗High cost without insurance coverage
✗Not available in all pharmacies

Choose Zepbound

Feature-by-feature comparison

Feature	Sesame Care	Zepbound
Monthly Price	$59	$450
Rating	8.7/10	9.3/10
Medications	semaglutide, tirzepatide, orforglipron	tirzepatide
Insurance Accepted	Yes	Yes
Support Hours	Not published	Mon-Fri 8AM-8PM ET
Live Chat	No	No
Free Shipping	No	No
Shipping Speed	Filled at your pharmacy; not shipped by Sesame	Varies by pharmacy
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Ongoing video visits, labs and messaging with a dedicated provider	As prescribed by physician
Money-back Guarantee	Full refund if you cancel at least 3 hours before your first visit; annual fees are non-refundable once paid	Savings card available for eligible patients
Cancellation Policy	Self-cancel monthly or annual subscriptions any time, but past months and annual fees are not refunded	Prescription-based, consult doctor

Which should you choose?

Choose Sesame Care if you:

→Want to save $391/month with a more affordable option
→Want more medication options to choose from
→Want personalized coaching support included
→Value: publishes cash prices dose by dose, which no other provider on this site does. zepbound kwikpen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start

Get started with Sesame Care

Choose Zepbound if you:

→Prefer a higher-rated service (9.3/10 vs 8.7/10)
→Value: fda-approved for chronic weight management

Get started with Zepbound

Website previews

Sesame Care

Sesame Care website

Zepbound

Zepbound website

Our recommendation

Zepbound comes out ahead with a higher rating of 9.3/10.

Get started with Zepbound

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