Shameless Care vs Ro
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Shameless Care vs Ro: Overview
Choosing between Shameless Care and Ro for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Shameless Care offers both semaglutide and tirzepatide at $109/month with a rating of 8/10. Ro also provides both semaglutide and tirzepatide at $149/month with a 8.6/10 rating.
With only a $40/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$40/mo
Rating Difference
0.6
Winner
Ro
Best For
Quality
Shameless Care
View full Shameless Care review →Rating
8/10
Monthly Price
$109Cheaper
Medications
sildenafiltadalafilapomorphinebremelanotideoxytocinvalacyclovirdoxycycline
Pros
- ✓The whole price list sits on the homepage with no intake required: 14-panel STI testing $279, ED from $109, DoxyPEP from $99, valacyclovir from $109, and UTI, bacterial vaginosis and yeast infection treatment at $63 each (checked July 28, 2026)
- ✓There are no subscriptions at all. 'No subscriptions. No recurring charges. Ever.' is stated on every product page, which removes the auto-renewal trap that affects most of this category
- ✓Every price is all-in: physician consult, prescription, medication and overnight or 2-day shipping are included with no separate consultation fee
- ✓The compounding disclosure is precise and correct, and appears on each compounded product rather than buried in a footer
- ✓Exact doses and beyond-use dates are published for compounded products - genuinely rare, and it lets you see how long a preparation is actually good for
- ✓The ED range clearly separates FDA-approved generic sildenafil and tadalafil from the compounded Duo and Trio blends, so you can choose a plain approved medicine if you prefer
- ✓The STI panel is clinically thoughtful. It includes oral and anal swabs and explains why: chlamydia and gonorrhoea can infect the throat or rectum, and urine-and-blood-only panels miss those infections entirely. Most direct-to-consumer STI kits do not collect those sites
- ✓Testing is physician-ordered with a named board-certified physician assigned, and results come 2-3 days after the lab receives your kit
- ✓Its own editorial is unusually candid about the industry it operates in, including a piece on 'The Uncomfortable Truth About Online ED Sales'
- ✓Compounded medication is made to order within three business days and shipped in insulated packaging at no extra cost
Cons
- ✗Prices are high relative to alternatives. DoxyPEP starts at $99 here against $22 at Wisp, and UTI treatment is $63 against Wisp's cheaper generics. You are paying a premium for the all-in, no-subscription model
- ✗The Trio blend stacks two PDE5 inhibitors - sildenafil and tadalafil - and adds apomorphine. Duo stacks the two PDE5 inhibitors. No FDA-approved product combines two PDE5 inhibitors, and doubling the same mechanism compounds the blood-pressure-lowering effect without established added benefit
- ✗Shameless Desire combines tadalafil with apomorphine and oxytocin. Apomorphine independently lowers blood pressure and causes nausea, so the combined hypotensive risk deserves a direct conversation with the prescriber
- ✗Bremelanotide is FDA-approved only as Vyleesi, an autoinjector for premenopausal women with hypoactive sexual desire disorder. Selling it as a compounded nasal spray for both men and women is a different route of administration and an off-label use
- ✗Oxytocin at 100 IU sublingually for desire has essentially no controlled trial evidence supporting it
- ✗The bremelanotide nasal spray carries a 30-day beyond-use date, so a $235 purchase has to be used quickly or wasted
- ✗The advertised '4.9-Star Rating' and '10,000+ patients served' could not be verified against any independent source
- ✗Not available in all 50 states - the site states 49
- ✗Anyone taking nitrates or riociguat must not use the PDE5-containing products, and the apomorphine-containing ones interact seriously with 5-HT3 anti-emetics such as ondansetron
Ro
View full Ro review →Rating
8.6/10Better
Monthly Price
$149
Medications
semaglutidetirzepatide
Pros
- ✓Prescribes FDA-approved, brand-name GLP-1s - Zepbound, Wegovy pen and pill, Ozempic, Saxenda and the new Foundayo pill - rather than compounded copies
- ✓Real insurance support: a dedicated team handles prior authorizations and appeals, and there is a free GLP-1 insurance checker you can run before paying anything
- ✓Publishes exact cash-pay prices for the Zepbound KwikPen: $299/mo at 2.5 mg, $399/mo at 5 mg and $449/mo at 7.5-15 mg with the manufacturer offer (checked July 26, 2026)
- ✓Membership is $39 for the first month, and as low as $74/mo if you prepay for a year
- ✓Long-established: trading since 2017, BBB accredited since 2018, and one of the largest telehealth platforms in the US
- ✓Prescriptions are typically filled and shipped within 1-4 days
- ✓Cash-pay Zepbound single-dose vials are available if you want to skip the insurance process entirely
- ✓Ongoing provider messaging, check-ins and progress tracking are included in the membership fee
Cons
- ✗The membership fee does not include your medication. At $149/mo month-to-month plus $449/mo for a maintenance dose of Zepbound, the realistic all-in cost is roughly $520-600 a month
- ✗The discounted $449 refill price depends on completing a check-in within 45 days of your last delivery. Miss that window and the price jumps to $499 for 7.5 mg, or $699 for the 10, 12.5 and 15 mg doses
- ✗All sales are final. Ro states it cannot issue refunds or accept returns on prescription products, except where it has made an error filling your prescription
- ✗The headline $74/mo membership rate requires prepaying a full year upfront
- ✗BBB lists 619 complaints, and Trustpilot sits at 3.8 from 4,796 reviews, with cancellation and billing the dominant negative themes
- ✗No customer phone number or support email is published on the site; support runs through your account
- ✗Because the medication price depends on your insurance, what you will actually pay each month cannot be known until after you have signed up and been assessed
- ✗The homepage claim 'Lose 20% body weight on average with Zepbound' comes from the manufacturer's trial of the branded drug, not from Ro's own patients
Feature-by-feature comparison
| Feature | Shameless Care | Ro |
|---|---|---|
| Monthly Price | $109 | $149 |
| Rating | 8/10 | 8.6/10 |
| Medications | sildenafil, tadalafil, apomorphine, bremelanotide, oxytocin, valacyclovir, doxycycline | semaglutide, tirzepatide |
| Insurance Accepted | No | Yes |
| Support Hours | Not published | On-demand provider messaging (hours not published) |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Made to order within three business days, then overnight or UPS 2nd Day Air in insulated packaging at no extra cost | Typically filled and shipped within 1-4 days |
| Mobile App | No | Available |
| Dedicated Coach | Not included | Included |
| Follow-up Frequency | Board-certified physician assigned from start to finish; ongoing cadence not published | Ongoing check-ins plus on-demand provider messaging |
| Money-back Guarantee | Advertises a '100% Service Guarantee' and '100% Satisfaction'; specific terms not published | None - Ro states all sales of prescription products are final, except where it filled your prescription in error |
| Cancellation Policy | No subscriptions - every purchase is one-off, so there is nothing to cancel | Cancel the membership before your next billing date; charges already processed are not refunded |
Which should you choose?
Choose Shameless Care if you:
- →Want to save $40/month with a more affordable option
- →Want more medication options to choose from
- →Value: the whole price list sits on the homepage with no intake required: 14-panel sti testing $279, ed from $109, doxypep from $99, valacyclovir from $109, and uti, bacterial vaginosis and yeast infection treatment at $63 each (checked july 28, 2026)
Choose Ro if you:
- →Prefer a higher-rated service (8.6/10 vs 8/10)
- →Need insurance coverage for your treatment
- →Want personalized coaching support included
- →Value: prescribes fda-approved, brand-name glp-1s - zepbound, wegovy pen and pill, ozempic, saxenda and the new foundayo pill - rather than compounded copies
Website previews
Shameless Care
Ro
Our recommendation
Ro comes out ahead with a higher rating of 8.6/10. It also provides multiple medication options including both semaglutide and tirzepatide.
Get started with RoRelated comparisons
Shameless Care vs CoreAge Rx
$109
★ 8
vs
$99
★ 9.6
Shameless Care vs Zepbound
$109
★ 8
vs
$450
★ 9.3
Shameless Care vs Mounjaro
$109
★ 8
vs
$1080
★ 9.2
Shameless Care vs Wegovy Pill
$109
★ 8
vs
$149
★ 9.2
Shameless Care vs Foundayo
$109
★ 8
vs
$149
★ 9.2
Shameless Care vs Wegovy
$109
★ 8
vs
$349
★ 9.1
Shameless Care vs NovoCare Pharmacy
$109
★ 8
vs
$149
★ 9
Shameless Care vs Ozempic
$109
★ 8
vs
$349
★ 8.9
Shameless Care vs Form Health
$109
★ 8
vs
$299
★ 8.8
Shameless Care vs Henry Meds
$109
★ 8
vs
$179
★ 8.7
Shameless Care vs Sesame Care
$109
★ 8
vs
$59
★ 8.7
Shameless Care vs FuturHealth
$109
★ 8
vs
$225
★ 8.7
Shameless Care vs Circle Medical
$109
★ 8
vs
$35
★ 8.7
Shameless Care vs Midi Health
$109
★ 8
vs
$164
★ 8.6
Shameless Care vs Noom Med
$109
★ 8
vs
$149
★ 8.6
Shameless Care vs Precision Telemed
$109
★ 8
vs
$150
★ 8.6
Shameless Care vs Hims
$109
★ 8
vs
$298
★ 8.5
Shameless Care vs Calibrate
$109
★ 8
vs
$199
★ 8.5
Shameless Care vs PlushCare
$109
★ 8
vs
$20
★ 8.5
Shameless Care vs LifeMD
$109
★ 8
vs
$199
★ 8.5
Compare other providers
Compare GLP-1 Brands
vs