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Shed vs Signos

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Shed vs Signos: Overview

Choosing between Shed and Signos for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Shed offers both semaglutide and tirzepatide at $159/month with a rating of 8.1/10. Signos offers continuous glucose monitoring at $127/month with a 7.8/10 rating.

With only a $32/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$32/mo

Rating Difference

0.3

Winner

Shed

Best For

Quality

Shed

View full Shed review →

Rating

8.1/10Better

Monthly Price

$159

Medications

semaglutidetirzepatide

Pros

✓Compounded semaglutide advertised from $159/mo and compounded tirzepatide from $239/mo, alongside brand-name Wegovy, Zepbound and the new Foundayo pill (checked July 26, 2026)
✓Three delivery formats: weekly injections, daily sublingual liquid drops and daily lozenges, so needle-free options are genuinely available
✓A 120-day weight loss guarantee that is actually written into the terms with defined conditions, rather than an unexplained banner claim
✓The arbitration clause and class action waiver can be opted out of within 30 days of accepting the terms
✓Buy-now-pay-later refunds are handled explicitly: Shed transmits refunds to Affirm, Klarna or Afterpay within three business days, and the terms state each lender's refund window
✓Non-GLP-1 options too - metformin, naltrexone, topiramate, MIC + B12 - so a provider has alternatives if a GLP-1 is not appropriate
✓Health coaching and a member success manager are part of the program, not an upsell
✓Members enrolled under a previous guarantee are grandfathered rather than moved to worse terms

Cons

✗The '120-Day Weight Loss Guarantee' is far more demanding than the asterisk suggests. To qualify you must log at least two weigh-ins a month (eight over the period), complete at least 50% of daily app check-ins - 60 days out of 120 - and submit every provider follow-up form on time. Miss the check-in quota and the guarantee lapses
✗The guarantee only pays out if you fail to lose 5% of your baseline body weight, so modest results still disqualify you from a refund
✗Trustpilot showed 1.8 out of 5, albeit from just 22 reviews - a small but uniformly poor public signal
✗Oral formats are not available in Alaska, Alabama, Arkansas, Connecticut, Indiana, Kentucky, Louisiana, Michigan, Minnesota, North Carolina, New Jersey, South Carolina, Virginia, Vermont, Wisconsin or West Virginia
✗'As low as $159' is a floor price; the site does not publish the plan ladder or say what commitment that rate requires
✗Shed's own product menu misspells its second GLP-1 as 'Compounded Trizepatide', which is not reassuring on a prescription page
✗The compounded products are not FDA-approved, and the '15%' and '20%' body-weight figures on the landing page come from trials of the branded drugs
✗Disputes go to binding arbitration unless you actively opt out in the first 30 days

Signos

View full Signos review →

Rating

7.8/10

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Feature-by-feature comparison

Feature	Shed	Signos
Monthly Price	$159	$127
Rating	8.1/10	7.8/10
Medications	semaglutide, tirzepatide	continuous glucose monitoring
Insurance Accepted	No	No
Support Hours	Not published	In-app dietitian chat; hours not published
Live Chat	No	Available
Free Shipping	Yes	Yes
Shipping Speed	Not published	Free shipping; six-month plans ship in three-month bundles
Mobile App	Available	Available
Dedicated Coach	Included	Included
Follow-up Frequency	Daily app check-ins expected under the guarantee, plus provider follow-up forms	Continuous glucose data with in-app dietitian support
Money-back Guarantee	120-day guarantee, but only if you complete 60 daily app check-ins, 8 weigh-ins and every provider form, and still fail to lose 5% of baseline body weight	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)
Cancellation Policy	Subscription based; refunds are governed by the 120-day guarantee conditions, with BNPL refunds transmitted within 3 business days	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused

Which should you choose?

Choose Shed if you:

→Prefer a higher-rated service (8.1/10 vs 7.8/10)
→Want more medication options to choose from
→Value: compounded semaglutide advertised from $159/mo and compounded tirzepatide from $239/mo, alongside brand-name wegovy, zepbound and the new foundayo pill (checked july 26, 2026)

Get started with Shed

Choose Signos if you:

→Want to save $32/month with a more affordable option
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Website previews

Shed

Shed website

Signos

Signos website

Our recommendation

Shed comes out ahead with a higher rating of 8.1/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Shed

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