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Shed vs Winona

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Shed vs Winona: Overview

Choosing between Shed and Winona for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

Shed offers both semaglutide and tirzepatide at $159/month with a rating of 8.1/10. Winona also provides both semaglutide and tirzepatide at $89/month with a 8.4/10 rating.

The price difference of $70/month is significant - Winona is the more budget-friendly option, while Shed positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$70/mo

Rating Difference

0.3

Winner

Winona

Best For

Budget

Shed

View full Shed review →

Rating

8.1/10

Monthly Price

$159

Medications

semaglutidetirzepatide

Pros

✓Compounded semaglutide advertised from $159/mo and compounded tirzepatide from $239/mo, alongside brand-name Wegovy, Zepbound and the new Foundayo pill (checked July 26, 2026)
✓Three delivery formats: weekly injections, daily sublingual liquid drops and daily lozenges, so needle-free options are genuinely available
✓A 120-day weight loss guarantee that is actually written into the terms with defined conditions, rather than an unexplained banner claim
✓The arbitration clause and class action waiver can be opted out of within 30 days of accepting the terms
✓Buy-now-pay-later refunds are handled explicitly: Shed transmits refunds to Affirm, Klarna or Afterpay within three business days, and the terms state each lender's refund window
✓Non-GLP-1 options too - metformin, naltrexone, topiramate, MIC + B12 - so a provider has alternatives if a GLP-1 is not appropriate
✓Health coaching and a member success manager are part of the program, not an upsell
✓Members enrolled under a previous guarantee are grandfathered rather than moved to worse terms

Cons

✗The '120-Day Weight Loss Guarantee' is far more demanding than the asterisk suggests. To qualify you must log at least two weigh-ins a month (eight over the period), complete at least 50% of daily app check-ins - 60 days out of 120 - and submit every provider follow-up form on time. Miss the check-in quota and the guarantee lapses
✗The guarantee only pays out if you fail to lose 5% of your baseline body weight, so modest results still disqualify you from a refund
✗Trustpilot showed 1.8 out of 5, albeit from just 22 reviews - a small but uniformly poor public signal
✗Oral formats are not available in Alaska, Alabama, Arkansas, Connecticut, Indiana, Kentucky, Louisiana, Michigan, Minnesota, North Carolina, New Jersey, South Carolina, Virginia, Vermont, Wisconsin or West Virginia
✗'As low as $159' is a floor price; the site does not publish the plan ladder or say what commitment that rate requires
✗Shed's own product menu misspells its second GLP-1 as 'Compounded Trizepatide', which is not reassuring on a prescription page
✗The compounded products are not FDA-approved, and the '15%' and '20%' body-weight figures on the landing page come from trials of the branded drugs
✗Disputes go to binding arbitration unless you actively opt out in the first 30 days

Winona

View full Winona review →

Rating

8.4/10Better

Monthly Price

$89Cheaper

Medications

bioidentical estradiolprogesteroneestriolDHEAsildenafilminoxidil

Pros

✓The full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked July 28, 2026)
✓Multiple delivery routes are offered - patch, body cream, vaginal cream, tablet and capsule - so treatment can be matched to preference rather than to whatever the company happens to stock
✓Winona owns its own 503A compounding pharmacies rather than outsourcing to a partner, which gives it direct control over formulation and consistency
✓Its pharmacy page explains the 503A/503B distinction correctly and states that 503A pharmacies are regulated by State Boards of Pharmacy, not the FDA - an accurate description that competitors routinely overstate
✓Roughly 8,000 Trustpilot reviews at 4.6, with 99% of negative reviews answered and a typical reply time under 24 hours
✓The rating advertised on site matches the rating on the public Trustpilot profile
✓The initial visit is free, so you can be assessed before paying for treatment
✓Editorial content carries numbered citations rather than unsourced assertions, and the site runs a public subreddit alongside a help centre and published phone number
✓HSA/FSA eligible, with a dedicated page explaining eligibility
✓Adjacent products are priced transparently too - DHEA from $27 per 3-month supply, sildenafil arousal cream at $79 per order, minoxidil hair serum at $150 per 3-month supply

Cons

✗Everything Winona dispenses is compounded in its own 503A pharmacies, which means it is not FDA-approved and has not been evaluated by the FDA for safety, efficacy or quality. The site explains 503A status clearly but does not foreground the 'not FDA-approved' consequence as plainly
✗Pharmaceutical products cannot be returned, per the terms - so once a prescription ships, you own it
✗The terms carry a mandatory arbitration clause on an individual basis with a class-action waiver, set out in capitals at the top of the document
✗Every headline price is a 'from' figure, so the actual monthly cost depends on the dose your clinician prescribes and is not knowable before the consultation
✗The hormone therapy explainer describes HRT as 'scientifically proven to be the safest, most effective treatment' for menopause symptoms. It is cited, but that is a strong framing for a therapy whose risk profile still depends heavily on age, time since menopause and personal history
✗Trustpilot notes Winona invites customers to review, which tends to lift scores relative to organic-only profiles, and that it may use AI-assisted replies
✗Systemic estrogen is not appropriate for everyone - women with a history of breast or endometrial cancer, unexplained vaginal bleeding, blood clots, stroke or liver disease should not start it without specialist input
✗Compounded hormone therapy in general lacks the long-term outcome data that exists for FDA-approved products, so the evidence cited for HRT as a class does not transfer automatically to these specific preparations

Feature-by-feature comparison

Feature	Shed	Winona
Monthly Price	$159	$89
Rating	8.1/10	8.4/10
Medications	semaglutide, tirzepatide	bioidentical estradiol, progesterone, estriol, DHEA, sildenafil, minoxidil
Insurance Accepted	No	No
Support Hours	Not published	Help centre and chat available; hours not published
Live Chat	No	Available
Free Shipping	Yes	Yes
Shipping Speed	Not published	Shipped to your door after clinician review; free shipping included
Mobile App	Available	No
Dedicated Coach	Included	Not included
Follow-up Frequency	Daily app check-ins expected under the guarantee, plus provider follow-up forms	Ongoing clinician access through the patient portal; cadence not published
Money-back Guarantee	120-day guarantee, but only if you complete 60 daily app check-ins, 8 weigh-ins and every provider form, and still fail to lose 5% of baseline body weight	None published; pharmaceutical products cannot be returned. A separate cancellation and refund policy governs subscriptions
Cancellation Policy	Subscription based; refunds are governed by the 120-day guarantee conditions, with BNPL refunds transmitted within 3 business days	Subscriptions can be cancelled from your account; a separate cancellation policy governs when it takes effect

Which should you choose?

Choose Shed if you:

→Want personalized coaching support included
→Value: compounded semaglutide advertised from $159/mo and compounded tirzepatide from $239/mo, alongside brand-name wegovy, zepbound and the new foundayo pill (checked july 26, 2026)

Get started with Shed

Choose Winona if you:

→Want to save $70/month with a more affordable option
→Prefer a higher-rated service (8.4/10 vs 8.1/10)
→Want more medication options to choose from
→Value: the full price list is published openly, with no intake required to see it: progesterone capsules from $39/mo, estrogen tablets from $54/mo, estrogen body cream (with progesterone) from $89/mo, vaginal estrogen cream from $89/mo and the estrogen patch from $149/mo (checked july 28, 2026)

Get started with Winona

Website previews

Shed

Shed website

Winona

Winona website

Our recommendation

Winona comes out ahead with a higher rating of 8.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Winona

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