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Strut Health vs Signos

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Strut Health vs Signos: Overview

Choosing between Strut Health and Signos for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

Strut Health offers both semaglutide and tirzepatide at $149/month with a rating of 8/10. Signos offers continuous glucose monitoring at $127/month with a 7.8/10 rating.

With only a $22/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$22/mo

Rating Difference

0.2

Winner

Strut Health

Best For

Quality

Strut Health

View full Strut Health review →

Rating

8/10Better

Monthly Price

$149

Medications

semaglutidetirzepatide

Pros

✓Compounded injectable semaglutide from $149/month and compounded tirzepatide from $199/month on auto-refill, with a 30-day tirzepatide supply listed at $325 without it (checked July 27, 2026)
✓Explains what compounded medication actually is, and why it is not FDA-approved, instead of burying a disclaimer - the clearest patient-facing explanation of the distinction we found
✓Free online MD visit, free shipping and free follow-up care are all included in the price
✓Damaged or defective orders can be reported within two weeks, far more workable than the 24 to 48-hour windows most competitors impose
✓Publishes a support email, a street address and actual support hours rather than a contact form alone
✓Oral semaglutide is offered alongside injectables, plus sermorelin for those who want a non-GLP-1 option
✓Cancel anytime, and the pricing page states plainly that medical necessity is required rather than implying everyone qualifies
✓Separate men's and women's weight-loss pathways, and a broad catalogue covering hair, skin, sexual health and menopause

Cons

✗The refund policy was last modified on 21 September 2021, years before Strut added its GLP-1 line, so the document governing your money predates the product you are buying
✗No returns or refunds once medication leaves the pharmacy, and no refund for cancellations received after the pharmacy has processed the order
✗The tirzepatide page places 'Just $6.63' beside a '30 DAY SUPPLY $325' heading. The $6.63 figure is the daily rate for the $199 auto-refill price, not for the $325 supply shown next to it
✗'As low as' pricing is tied to committing to auto-refill, and the site does not show what a single non-recurring order costs for semaglutide
✗There is no independent review signal at all - no Trustpilot profile, no BBB file - so nothing external corroborates the service quality
✗GLP-1 sits inside a large catalogue spanning hair, skin and sexual health, so the weight-loss programme gets less dedicated clinical content than a specialist provider offers
✗Support runs weekdays 9am-5pm ET only, with no evening, weekend or phone coverage published
✗Compounded products carry the usual caveat that they have not been evaluated by the FDA for safety, efficacy or quality

Choose Strut Health

Signos

View full Signos review →

Rating

7.8/10

Monthly Price

$127Cheaper

Medications

continuous glucose monitoring

Pros

✓A genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription
✓Published plan pricing: $127/month on the longest plan, $150/month on the mid plan and $225/month on the shortest, each discounted from a higher list price
✓Two CGM sensors per month are included in every plan
✓HSA/FSA eligible, which matters at these prices
✓Registered dietitian support is included, with in-app chat and the option of a face-to-face session
✓A 30-day results guarantee: if you do not learn something new about how your body loses weight, a senior Signos coach audits your data free, described as a $250 value
✓One membership covers the sensors, the app, the coaching and the behaviour-change programme instead of stacking separate subscriptions
✓It pairs sensibly with a GLP-1 rather than competing with one, and the company states medication costs are included in the Signos programme where applicable
✓Stress and sleep tracking are built in alongside glucose

Cons

✗This is not a GLP-1 prescribing service in the way the rest of this site is. If you came here for a semaglutide prescription, Signos is a different kind of product
✗The cheapest per-month rate requires the longest commitment, and six-month plans ship in three-month bundles
✗CGM-guided eating for weight loss in people without diabetes has far weaker evidence behind it than GLP-1 medication
✗HSA/FSA eligibility is qualified - "Possibly, but it depends on your HSA/FSA provider" - and Signos states it is not responsible for reimbursement, with the cancellation policy still applying if your provider refuses
✗The results guarantee pays out in a free data audit, not money back
✗Outcome claims reflect individual Signos patient experiences rather than published clinical studies, which the company discloses
✗Not suitable if you are on insulin without speaking to your own clinician first, which the signup flow asks you to confirm

Feature-by-feature comparison

Feature	Strut Health	Signos
Monthly Price	$149	$127
Rating	8/10	7.8/10
Medications	semaglutide, tirzepatide	continuous glucose monitoring
Insurance Accepted	No	No
Support Hours	Mon-Fri 9am-5pm ET	In-app dietitian chat; hours not published
Live Chat	Available	Available
Free Shipping	Yes	Yes
Shipping Speed	Not published	Free shipping; six-month plans ship in three-month bundles
Mobile App	No	Available
Dedicated Coach	Not included	Included
Follow-up Frequency	Free follow-up care included	Continuous glucose data with in-app dietitian support
Money-back Guarantee	None - no refunds once medication leaves the pharmacy; defective or damaged orders can be reported within two weeks	30-day results guarantee - if you do not learn something new about how your body loses weight, a senior coach audits your data free (stated as a $250 value)
Cancellation Policy	Cancel anytime, but not after the pharmacy has processed your order	Subscription plans; cancellation terms apply even if HSA/FSA reimbursement is refused

Which should you choose?

Choose Strut Health if you:

→Prefer a higher-rated service (8/10 vs 7.8/10)
→Want more medication options to choose from
→Value: compounded injectable semaglutide from $149/month and compounded tirzepatide from $199/month on auto-refill, with a 30-day tirzepatide supply listed at $325 without it (checked july 27, 2026)

Get started with Strut Health

Choose Signos if you:

→Want to save $22/month with a more affordable option
→Want personalized coaching support included
→Value: a genuinely different approach: a continuous glucose monitor plus an app that tells you how your own body responds to specific foods, rather than a prescription subscription

Get started with Signos

Website previews

Strut Health

Strut Health website

Signos

Signos website

Our recommendation

Strut Health comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Strut Health

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