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SynergyRX vs MadeMed

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

SynergyRX vs MadeMed: Overview

Choosing between SynergyRX and MadeMed for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

SynergyRX offers both semaglutide and tirzepatide at $199/month with a rating of 7.4/10. MadeMed also provides both semaglutide and tirzepatide at $239/month with a 7.3/10 rating.

With only a $40/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$40/mo

Rating Difference

0.1

Winner

SynergyRX

Best For

Budget

SynergyRX

View full SynergyRX review →

Rating

7.4/10Better

Monthly Price

$199Cheaper

Medications

semaglutidetirzepatide

Pros

✓A complete GLP-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked July 27, 2026)
✓Brand-name options are priced too, and Ozempic at $499 is notably cheaper here than Wegovy or Mounjaro at $947
✓Oral dissolving tablet versions of both molecules are available for people who will not inject
✓A $100 welcome credit is applied automatically at checkout with no code to hunt for
✓FSA and HSA eligible, with free shipping
✓The FAQ explicitly raises the compounded-versus-brand-name question rather than avoiding it
✓Longevity, hair, skin and sexual health lines are available from the same provider

Cons

✗On a weight-loss landing page, the product carousel opens on the longevity tab. Every GLP-1 and its price is hidden behind a 'WEIGHT LOSS' tab you have to find and click - a visitor who does not spot it sees only NAD+, sermorelin, glutathione, B12 and PT-141
✗There is no public review footprint at all - no Trustpilot profile, no BBB file - against a claim of 50,000+ patients
✗The oral tablets cost more than the injections ($299 against $199 for semaglutide), the reverse of how most competitors price them, with no explanation given
✗The call-to-action button reads 'SEE IF I'M ELLIGIBLE' - misspelled, and repeated twice on the page
✗The headline - 'The Proven Way to lose 15% of your body weight fast! Lose 1-2lbs per week' - is word-for-word the copy used by TrimRx and Embody, indicating a shared white-label funnel rather than an independently written site
✗The testimonial block under a weight-loss heading mixes weight-loss quotes with an NAD+ energy testimonial, and the same three quotes repeat on a loop
✗No refund or cancellation policy could be found anywhere on the site
✗No published phone number, support email or support hours

Choose SynergyRX

MadeMed

View full MadeMed review →

Rating

7.3/10

Monthly Price

$239

Medications

semaglutidetirzepatide

Pros

✓The compounded disclaimer is explicit and sits on the product page itself, not in a distant footer
✓It directs patients to the FDA's adverse event reporting line (1-800-FDA-1088), which almost no competitor does
✓A real customer phone number is published rather than a contact form alone
✓Both semaglutide and tirzepatide are offered in injectable and oral forms
✓Quarterly billing at the starting dose is inexpensive - $239 per refill billed every three months for injectable semaglutide, and $399 for injectable tirzepatide (checked July 27, 2026)
✓The pricing footnote is honest about what it covers: 'Advertised pricing reflects the starting dosage'
✓Peptide and NAD+ lines are available alongside weight care

Cons

✗The monthly purchase option displays a price of '$0*/month'. On the primary buying path for the flagship product, the price simply does not render
✗Pricing is not flat across doses. The footnote states 'Actual price depends on the dosage prescribed by your provider', so the advertised figure applies only at the starting dose and rises as you titrate up - the opposite of the flat-price model most competitors offer, and a significant cost risk over a year
✗The '4.8/5' rating shown on product pages has no traceable source, and no Trustpilot profile exists for the domain
✗The homepage is effectively a navigation shell - it carries menus and a phone number but almost no content, pricing or explanation
✗Product pages are only reachable at bare paths such as /injectable-semaglutide; the more conventional /products/ and /weight-loss/ paths return empty shells
✗No refund or cancellation policy could be found beyond a 'Returns' link
✗No support hours are published, and there is no independent complaint record of any kind
✗Because the real cost depends on the dose you end up on, you cannot work out what a year of treatment will cost before signing up

Feature-by-feature comparison

Feature	SynergyRX	MadeMed
Monthly Price	$199	$239
Rating	7.4/10	7.3/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Fast, free shipping claimed	Not published
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Not published	Board-certified physician review; follow-up frequency not published
Money-back Guarantee	None published	None published; only a 'Returns' link is provided
Cancellation Policy	Not published	Not published; billing is monthly or quarterly per refill

Which should you choose?

Choose SynergyRX if you:

→Want to save $40/month with a more affordable option
→Prefer a higher-rated service (7.4/10 vs 7.3/10)
→Value: a complete glp-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked july 27, 2026)

Get started with SynergyRX

Choose MadeMed if you:

→Value: the compounded disclaimer is explicit and sits on the product page itself, not in a distant footer

Get started with MadeMed

Website previews

SynergyRX

SynergyRX website

MadeMed

MadeMed website

Our recommendation

SynergyRX comes out ahead with a higher rating of 7.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with SynergyRX

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