← All providers

SynergyRX vs Shed

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

SynergyRX vs Shed: Overview

Choosing between SynergyRX and Shed for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

SynergyRX offers both semaglutide and tirzepatide at $199/month with a rating of 7.4/10. Shed also provides both semaglutide and tirzepatide at $159/month with a 8.1/10 rating.

With only a $40/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$40/mo

Rating Difference

0.7

Winner

Shed

Best For

Budget

SynergyRX

View full SynergyRX review →

Rating

7.4/10

Monthly Price

$199

Medications

semaglutidetirzepatide

Pros

✓A complete GLP-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked July 27, 2026)
✓Brand-name options are priced too, and Ozempic at $499 is notably cheaper here than Wegovy or Mounjaro at $947
✓Oral dissolving tablet versions of both molecules are available for people who will not inject
✓A $100 welcome credit is applied automatically at checkout with no code to hunt for
✓FSA and HSA eligible, with free shipping
✓The FAQ explicitly raises the compounded-versus-brand-name question rather than avoiding it
✓Longevity, hair, skin and sexual health lines are available from the same provider

Cons

✗On a weight-loss landing page, the product carousel opens on the longevity tab. Every GLP-1 and its price is hidden behind a 'WEIGHT LOSS' tab you have to find and click - a visitor who does not spot it sees only NAD+, sermorelin, glutathione, B12 and PT-141
✗There is no public review footprint at all - no Trustpilot profile, no BBB file - against a claim of 50,000+ patients
✗The oral tablets cost more than the injections ($299 against $199 for semaglutide), the reverse of how most competitors price them, with no explanation given
✗The call-to-action button reads 'SEE IF I'M ELLIGIBLE' - misspelled, and repeated twice on the page
✗The headline - 'The Proven Way to lose 15% of your body weight fast! Lose 1-2lbs per week' - is word-for-word the copy used by TrimRx and Embody, indicating a shared white-label funnel rather than an independently written site
✗The testimonial block under a weight-loss heading mixes weight-loss quotes with an NAD+ energy testimonial, and the same three quotes repeat on a loop
✗No refund or cancellation policy could be found anywhere on the site
✗No published phone number, support email or support hours

Choose SynergyRX

Shed

View full Shed review →

Rating

8.1/10Better

Monthly Price

$159Cheaper

Medications

semaglutidetirzepatide

Pros

✓Compounded semaglutide advertised from $159/mo and compounded tirzepatide from $239/mo, alongside brand-name Wegovy, Zepbound and the new Foundayo pill (checked July 26, 2026)
✓Three delivery formats: weekly injections, daily sublingual liquid drops and daily lozenges, so needle-free options are genuinely available
✓A 120-day weight loss guarantee that is actually written into the terms with defined conditions, rather than an unexplained banner claim
✓The arbitration clause and class action waiver can be opted out of within 30 days of accepting the terms
✓Buy-now-pay-later refunds are handled explicitly: Shed transmits refunds to Affirm, Klarna or Afterpay within three business days, and the terms state each lender's refund window
✓Non-GLP-1 options too - metformin, naltrexone, topiramate, MIC + B12 - so a provider has alternatives if a GLP-1 is not appropriate
✓Health coaching and a member success manager are part of the program, not an upsell
✓Members enrolled under a previous guarantee are grandfathered rather than moved to worse terms

Cons

✗The '120-Day Weight Loss Guarantee' is far more demanding than the asterisk suggests. To qualify you must log at least two weigh-ins a month (eight over the period), complete at least 50% of daily app check-ins - 60 days out of 120 - and submit every provider follow-up form on time. Miss the check-in quota and the guarantee lapses
✗The guarantee only pays out if you fail to lose 5% of your baseline body weight, so modest results still disqualify you from a refund
✗Trustpilot showed 1.8 out of 5, albeit from just 22 reviews - a small but uniformly poor public signal
✗Oral formats are not available in Alaska, Alabama, Arkansas, Connecticut, Indiana, Kentucky, Louisiana, Michigan, Minnesota, North Carolina, New Jersey, South Carolina, Virginia, Vermont, Wisconsin or West Virginia
✗'As low as $159' is a floor price; the site does not publish the plan ladder or say what commitment that rate requires
✗Shed's own product menu misspells its second GLP-1 as 'Compounded Trizepatide', which is not reassuring on a prescription page
✗The compounded products are not FDA-approved, and the '15%' and '20%' body-weight figures on the landing page come from trials of the branded drugs
✗Disputes go to binding arbitration unless you actively opt out in the first 30 days

Feature-by-feature comparison

Feature	SynergyRX	Shed
Monthly Price	$199	$159
Rating	7.4/10	8.1/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Fast, free shipping claimed	Not published
Mobile App	No	Available
Dedicated Coach	Not included	Included
Follow-up Frequency	Not published	Daily app check-ins expected under the guarantee, plus provider follow-up forms
Money-back Guarantee	None published	120-day guarantee, but only if you complete 60 daily app check-ins, 8 weigh-ins and every provider form, and still fail to lose 5% of baseline body weight
Cancellation Policy	Not published	Subscription based; refunds are governed by the 120-day guarantee conditions, with BNPL refunds transmitted within 3 business days

Which should you choose?

Choose SynergyRX if you:

→Value: a complete glp-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked july 27, 2026)

Get started with SynergyRX

Choose Shed if you:

→Want to save $40/month with a more affordable option
→Prefer a higher-rated service (8.1/10 vs 7.4/10)
→Want personalized coaching support included
→Value: compounded semaglutide advertised from $159/mo and compounded tirzepatide from $239/mo, alongside brand-name wegovy, zepbound and the new foundayo pill (checked july 26, 2026)

Get started with Shed

Website previews

SynergyRX

SynergyRX website

Shed

Shed website

Our recommendation

Shed comes out ahead with a higher rating of 8.1/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Shed

Related comparisons

SynergyRX vs CoreAge Rx

SynergyRX vs Zepbound

SynergyRX vs Mounjaro

SynergyRX vs Wegovy Pill

SynergyRX vs Foundayo

SynergyRX vs Wegovy

SynergyRX vs NovoCare Pharmacy

SynergyRX vs Ozempic

SynergyRX vs Form Health

SynergyRX vs Henry Meds

SynergyRX vs Sesame Care

SynergyRX vs FuturHealth

SynergyRX vs Circle Medical

SynergyRX vs Ro

SynergyRX vs Midi Health

SynergyRX vs Noom Med

SynergyRX vs Precision Telemed

SynergyRX vs Hims

SynergyRX vs Calibrate

SynergyRX vs PlushCare

Compare other providers

Compare GLP-1 Brands

First Brand

vs

Second Brand