SynergyRX vs System Labs
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
SynergyRX vs System Labs: Overview
Choosing between SynergyRX and System Labs for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
SynergyRX offers both semaglutide and tirzepatide at $199/month with a rating of 7.4/10. System Labs also provides both semaglutide and tirzepatide at $149/month with a 6.5/10 rating.
With only a $50/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$50/mo
Rating Difference
0.9
Winner
SynergyRX
Best For
Quality
SynergyRX
View full SynergyRX review →Rating
7.4/10Better
Monthly Price
$199
Medications
semaglutidetirzepatide
Pros
- ✓A complete GLP-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked July 27, 2026)
- ✓Brand-name options are priced too, and Ozempic at $499 is notably cheaper here than Wegovy or Mounjaro at $947
- ✓Oral dissolving tablet versions of both molecules are available for people who will not inject
- ✓A $100 welcome credit is applied automatically at checkout with no code to hunt for
- ✓FSA and HSA eligible, with free shipping
- ✓The FAQ explicitly raises the compounded-versus-brand-name question rather than avoiding it
- ✓Longevity, hair, skin and sexual health lines are available from the same provider
Cons
- ✗On a weight-loss landing page, the product carousel opens on the longevity tab. Every GLP-1 and its price is hidden behind a 'WEIGHT LOSS' tab you have to find and click - a visitor who does not spot it sees only NAD+, sermorelin, glutathione, B12 and PT-141
- ✗There is no public review footprint at all - no Trustpilot profile, no BBB file - against a claim of 50,000+ patients
- ✗The oral tablets cost more than the injections ($299 against $199 for semaglutide), the reverse of how most competitors price them, with no explanation given
- ✗The call-to-action button reads 'SEE IF I'M ELLIGIBLE' - misspelled, and repeated twice on the page
- ✗The headline - 'The Proven Way to lose 15% of your body weight fast! Lose 1-2lbs per week' - is word-for-word the copy used by TrimRx and Embody, indicating a shared white-label funnel rather than an independently written site
- ✗The testimonial block under a weight-loss heading mixes weight-loss quotes with an NAD+ energy testimonial, and the same three quotes repeat on a loop
- ✗No refund or cancellation policy could be found anywhere on the site
- ✗No published phone number, support email or support hours
System Labs
View full System Labs review →Rating
6.5/10
Monthly Price
$149Cheaper
Medications
NAD+sermorelinglutathioneMIC + B12GHK-Cu
Pros
- ✓Prices are published openly for every product, with the renewal rate shown alongside the introductory one: NAD+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, MIC + B12 $89/mo and GHK-Cu cream $109/mo (checked July 28, 2026)
- ✓Three delivery formats for NAD+ - injection, nasal spray and liposomal liquid - so needle-free options exist
- ✓Products are described as American made and third-party tested
- ✓The intake is short and a licensed provider reviews it before anything ships, with free 2-day shipping
- ✓No insurance required and no membership fee stacked on top of the product price
Cons
- ✗This is not a GLP-1 weight loss service. System Labs sells no semaglutide, no tirzepatide and no GLP-1 of any kind - the words do not appear anywhere on its site. If you are shopping for weight loss medication, this provider cannot supply it
- ✗We could not find any statement that the compounded peptides are not FDA-approved. That disclosure is standard across this category and its absence is the single biggest gap on the site
- ✗There is no refund or cancellation policy published at all - only a privacy policy and terms page
- ✗No independent review signal exists: no Trustpilot profile, no BBB file, and no rating displayed on site
- ✗Introductory pricing roughly doubles at renewal on most products, and the renewal price is the one you will pay for the rest of the course
- ✗Sermorelin, GHK-Cu and high-dose NAD+ have limited published human trial evidence for the benefits implied - 'perform 10 years younger' style claims are not supported by the kind of trials that back GLP-1 medications
- ✗No published phone number, support hours or physical address
- ✗The 'up to 1600mg' NAD+ potency claim is presented as an advantage without any evidence that higher doses produce better outcomes
Feature-by-feature comparison
| Feature | SynergyRX | System Labs |
|---|---|---|
| Monthly Price | $199 | $149 |
| Rating | 7.4/10 | 6.5/10 |
| Medications | semaglutide, tirzepatide | NAD+, sermorelin, glutathione, MIC + B12, GHK-Cu |
| Insurance Accepted | No | No |
| Support Hours | Not published | Medical team availability advertised; hours not published |
| Live Chat | No | Available |
| Free Shipping | Yes | Yes |
| Shipping Speed | Fast, free shipping claimed | Free 2-day shipping |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Not published | Ongoing clinician support advertised; frequency not published |
| Money-back Guarantee | None published | None published |
| Cancellation Policy | Not published | Not published |
Which should you choose?
Choose SynergyRX if you:
- →Prefer a higher-rated service (7.4/10 vs 6.5/10)
- →Value: a complete glp-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked july 27, 2026)
Choose System Labs if you:
- →Want to save $50/month with a more affordable option
- →Want more medication options to choose from
- →Value: prices are published openly for every product, with the renewal rate shown alongside the introductory one: nad+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, mic + b12 $89/mo and ghk-cu cream $109/mo (checked july 28, 2026)
Website previews
SynergyRX
System Labs
Our recommendation
SynergyRX comes out ahead with a higher rating of 7.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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