SynergyRX vs US Scripts MD
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
SynergyRX vs US Scripts MD: Overview
Choosing between SynergyRX and US Scripts MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
SynergyRX offers both semaglutide and tirzepatide at $199/month with a rating of 7.4/10. US Scripts MD also provides both semaglutide and tirzepatide at $299/month with a 7/10 rating.
The price difference of $100/month is significant - SynergyRX is the more budget-friendly option, while US Scripts MD positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$100/mo
Rating Difference
0.4
Winner
SynergyRX
Best For
Budget
SynergyRX
View full SynergyRX review →Rating
7.4/10Better
Monthly Price
$199Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓A complete GLP-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked July 27, 2026)
- ✓Brand-name options are priced too, and Ozempic at $499 is notably cheaper here than Wegovy or Mounjaro at $947
- ✓Oral dissolving tablet versions of both molecules are available for people who will not inject
- ✓A $100 welcome credit is applied automatically at checkout with no code to hunt for
- ✓FSA and HSA eligible, with free shipping
- ✓The FAQ explicitly raises the compounded-versus-brand-name question rather than avoiding it
- ✓Longevity, hair, skin and sexual health lines are available from the same provider
Cons
- ✗On a weight-loss landing page, the product carousel opens on the longevity tab. Every GLP-1 and its price is hidden behind a 'WEIGHT LOSS' tab you have to find and click - a visitor who does not spot it sees only NAD+, sermorelin, glutathione, B12 and PT-141
- ✗There is no public review footprint at all - no Trustpilot profile, no BBB file - against a claim of 50,000+ patients
- ✗The oral tablets cost more than the injections ($299 against $199 for semaglutide), the reverse of how most competitors price them, with no explanation given
- ✗The call-to-action button reads 'SEE IF I'M ELLIGIBLE' - misspelled, and repeated twice on the page
- ✗The headline - 'The Proven Way to lose 15% of your body weight fast! Lose 1-2lbs per week' - is word-for-word the copy used by TrimRx and Embody, indicating a shared white-label funnel rather than an independently written site
- ✗The testimonial block under a weight-loss heading mixes weight-loss quotes with an NAD+ energy testimonial, and the same three quotes repeat on a loop
- ✗No refund or cancellation policy could be found anywhere on the site
- ✗No published phone number, support email or support hours
US Scripts MD
View full US Scripts MD review →Rating
7/10
Monthly Price
$299
Medications
liraglutidesemaglutide
Pros
- ✓One of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting GLP-1
- ✓No price increase as your dose rises: "we keep our prices as low as possible and don't increase prices for high doses"
- ✓Free consultation, prescription, ongoing support and shipping are all bundled into the programme price
- ✓Free overnight, temperature-controlled shipping - genuine cold-chain handling rather than "ships fast"
- ✓An injection kit with spare syringes is included in every shipment
- ✓Anti-nausea medication is included with your first order, which is a thoughtful touch given how common GI side effects are
- ✓24/7 access to board-certified doctor support is advertised
- ✓You can cancel any time before your order ships, and there is a full refund if the providers decide you are not a fit for the programme
- ✓A $100 discount on the first month of weight-loss treatment
Cons
- ✗Expensive, and it gets more expensive: $299 for the first month, then $349/month thereafter
- ✗The alternative framing - "starter doses as low as $9.97/day" - is a per-day figure that works out to roughly $300 a month, which is not obviously cheap
- ✗Liraglutide is a daily injection and produced around 8% mean weight loss in the SCALE trial, meaningfully less than semaglutide or tirzepatide achieved in theirs
- ✗The medication is compounded and not FDA-approved
- ✗The refund guarantee only covers being declined - there is no satisfaction refund once you are on treatment
- ✗The dispensing pharmacy is not named
- ✗No insurance billing, and HSA/FSA acceptance is not stated
- ✗No published phone number
Feature-by-feature comparison
| Feature | SynergyRX | US Scripts MD |
|---|---|---|
| Monthly Price | $199 | $299 |
| Rating | 7.4/10 | 7/10 |
| Medications | semaglutide, tirzepatide | liraglutide, semaglutide |
| Insurance Accepted | No | No |
| Support Hours | Not published | Company advertises 24/7 access to partnering board-certified doctors |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Fast, free shipping claimed | Free overnight shipping in temperature-controlled packaging |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Not published | 24/7 access to partnering board-certified doctors for questions and support |
| Money-back Guarantee | None published | Full refund if the medical providers determine you are not a fit for the programme |
| Cancellation Policy | Not published | Cancel any time before your order ships; no contracts |
Which should you choose?
Choose SynergyRX if you:
- →Want to save $100/month with a more affordable option
- →Prefer a higher-rated service (7.4/10 vs 7/10)
- →Value: a complete glp-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked july 27, 2026)
Choose US Scripts MD if you:
- →Value: one of very few telehealth providers offering liraglutide, which suits people who cannot tolerate weekly dosing or who need a shorter-acting glp-1
Website previews
SynergyRX
US Scripts MD
Our recommendation
SynergyRX comes out ahead with a higher rating of 7.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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