System Labs vs Amie
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
System Labs vs Amie: Overview
Choosing between System Labs and Amie for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
System Labs offers both semaglutide and tirzepatide at $149/month with a rating of 6.5/10. Amie also provides both semaglutide and tirzepatide at $99/month with a 6.5/10 rating.
With only a $50/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$50/mo
Rating Difference
0.0
Winner
Amie
Best For
Budget
System Labs
View full System Labs review →Rating
6.5/10
Monthly Price
$149
Medications
NAD+sermorelinglutathioneMIC + B12GHK-Cu
Pros
- ✓Prices are published openly for every product, with the renewal rate shown alongside the introductory one: NAD+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, MIC + B12 $89/mo and GHK-Cu cream $109/mo (checked July 28, 2026)
- ✓Three delivery formats for NAD+ - injection, nasal spray and liposomal liquid - so needle-free options exist
- ✓Products are described as American made and third-party tested
- ✓The intake is short and a licensed provider reviews it before anything ships, with free 2-day shipping
- ✓No insurance required and no membership fee stacked on top of the product price
Cons
- ✗This is not a GLP-1 weight loss service. System Labs sells no semaglutide, no tirzepatide and no GLP-1 of any kind - the words do not appear anywhere on its site. If you are shopping for weight loss medication, this provider cannot supply it
- ✗We could not find any statement that the compounded peptides are not FDA-approved. That disclosure is standard across this category and its absence is the single biggest gap on the site
- ✗There is no refund or cancellation policy published at all - only a privacy policy and terms page
- ✗No independent review signal exists: no Trustpilot profile, no BBB file, and no rating displayed on site
- ✗Introductory pricing roughly doubles at renewal on most products, and the renewal price is the one you will pay for the rest of the course
- ✗Sermorelin, GHK-Cu and high-dose NAD+ have limited published human trial evidence for the benefits implied - 'perform 10 years younger' style claims are not supported by the kind of trials that back GLP-1 medications
- ✗No published phone number, support hours or physical address
- ✗The 'up to 1600mg' NAD+ potency claim is presented as an advantage without any evidence that higher doses produce better outcomes
Amie
View full Amie review →Rating
6.5/10
Monthly Price
$99Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓Pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
- ✓No shipment unless a provider approves you, stated on the pricing panel
- ✓Optional add-ons are priced separately and openly rather than bundled in silently
Cons
- ✗The FDA has formally told Amie that its website misrepresented its compounded products - see the warning letter above
- ✗The medication is compounded and therefore not FDA-approved - the agency has not reviewed it for safety, effectiveness or manufacturing quality
- ✗Compounded GLP-1 pricing in this tier is cheap partly because the product carries none of the trial programme, patent or distribution costs of the approved drug - and none of its regulatory review either
- ✗The three-month rate requires paying $249 up front
- ✗No phone number or support hours published
Feature-by-feature comparison
| Feature | System Labs | Amie |
|---|---|---|
| Monthly Price | $149 | $99 |
| Rating | 6.5/10 | 6.5/10 |
| Medications | NAD+, sermorelin, glutathione, MIC + B12, GHK-Cu | semaglutide, tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | Medical team availability advertised; hours not published | Not published |
| Live Chat | Available | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free 2-day shipping | Not published; no shipment unless approved |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Ongoing clinician support advertised; frequency not published | Not published |
| Money-back Guarantee | None published | None published |
| Cancellation Policy | Not published | Monthly or 3-month plans; terms not summarised on the pricing panel |
Which should you choose?
Choose System Labs if you:
- →Want more medication options to choose from
- →Value: prices are published openly for every product, with the renewal rate shown alongside the introductory one: nad+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, mic + b12 $89/mo and ghk-cu cream $109/mo (checked july 28, 2026)
Choose Amie if you:
- →Want to save $50/month with a more affordable option
- →Value: pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
Website previews
System Labs
Amie
Our recommendation
Amie offers better value at $99/month while maintaining strong ratings. It also provides multiple medication options including both semaglutide and tirzepatide.
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