← All providers

System Labs vs Enhance MD

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

System Labs vs Enhance MD: Overview

Choosing between System Labs and Enhance MD for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

System Labs offers both semaglutide and tirzepatide at $149/month with a rating of 6.5/10. Enhance MD also provides both semaglutide and tirzepatide at $212/month with a 7.7/10 rating.

The price difference of $63/month is significant - System Labs is the more budget-friendly option, while Enhance MD positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$63/mo

Rating Difference

1.2

Winner

Enhance MD

Best For

Quality

System Labs

View full System Labs review →

Rating

6.5/10

Monthly Price

$149Cheaper

Medications

NAD+sermorelinglutathioneMIC + B12GHK-Cu

Pros

✓Prices are published openly for every product, with the renewal rate shown alongside the introductory one: NAD+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, MIC + B12 $89/mo and GHK-Cu cream $109/mo (checked July 28, 2026)
✓Three delivery formats for NAD+ - injection, nasal spray and liposomal liquid - so needle-free options exist
✓Products are described as American made and third-party tested
✓The intake is short and a licensed provider reviews it before anything ships, with free 2-day shipping
✓No insurance required and no membership fee stacked on top of the product price

Cons

✗This is not a GLP-1 weight loss service. System Labs sells no semaglutide, no tirzepatide and no GLP-1 of any kind - the words do not appear anywhere on its site. If you are shopping for weight loss medication, this provider cannot supply it
✗We could not find any statement that the compounded peptides are not FDA-approved. That disclosure is standard across this category and its absence is the single biggest gap on the site
✗There is no refund or cancellation policy published at all - only a privacy policy and terms page
✗No independent review signal exists: no Trustpilot profile, no BBB file, and no rating displayed on site
✗Introductory pricing roughly doubles at renewal on most products, and the renewal price is the one you will pay for the rest of the course
✗Sermorelin, GHK-Cu and high-dose NAD+ have limited published human trial evidence for the benefits implied - 'perform 10 years younger' style claims are not supported by the kind of trials that back GLP-1 medications
✗No published phone number, support hours or physical address
✗The 'up to 1600mg' NAD+ potency claim is presented as an advantage without any evidence that higher doses produce better outcomes

Choose System Labs

Enhance MD

View full Enhance MD review →

Rating

7.7/10Better

Monthly Price

$212

Medications

semaglutidetirzepatide

Pros

✓One price at every dose, stated as 'One consistent price from your first dose to your last', so titrating up never raises the bill
✓Full tier pricing is published: GLP-1 Core (semaglutide) $112 first month then $212/mo, Advanced (tirzepatide) $180 then $280/mo, and microdosing tirzepatide at $169/mo (checked July 27, 2026)
✓The compounded, not-FDA-approved disclosure is unambiguous and placed next to the products rather than in a footer
✓Product images are labelled 'Not actual vial - For marketing purposes only'
✓The microdosing option is framed honestly, stating it suits patients seeking longevity benefits and that 'weight loss may occur, but isn't the primary aim' rather than overselling it
✓Medication ships quarterly, so there are fewer delivery events to manage
✓Discount codes and their terms are stated plainly - $100 off 3+ month plans, $50 off monthly

Cons

✗Enhance MD sells a combined semaglutide plus tirzepatide product, marketed as 'GLP-1 Elite' at $322/month. No published clinical trial evaluates taking these two medicines together; both act on the GLP-1 receptor, so stacking them plausibly compounds gastrointestinal side effects without established additional benefit. Anyone considering it should discuss the evidence base with an independent clinician first
✗The '100% Money-back guarantee' is not a money-back guarantee. Its own wording limits it to onboarding: 'If at any point during the onboarding process your provider finds you ineligible for medication, Enhance.MD will provide a refund.' Once you are prescribed, it does not apply
✗First-month pricing nearly doubles at renewal - $112 becomes $212 for semaglutide and $180 becomes $280 for tirzepatide
✗Trustpilot carries 159 reviews against a claim of 10,000+ patients transformed
✗This offer is not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee or West Virginia - eleven states
✗No published customer phone number or support hours
✗No BBB profile or independent complaint record to check
✗Quarterly shipping means committing to a longer supply of a medication you may not tolerate

Choose Enhance MD

Feature-by-feature comparison

Feature	System Labs	Enhance MD
Monthly Price	$149	$212
Rating	6.5/10	7.7/10
Medications	NAD+, sermorelin, glutathione, MIC + B12, GHK-Cu	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Medical team availability advertised; hours not published	Not published
Live Chat	Available	No
Free Shipping	Yes	Yes
Shipping Speed	Free 2-day shipping	Medication shipped every 12 weeks
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing clinician support advertised; frequency not published	Ongoing provider care and support included
Money-back Guarantee	None published	Advertised as a 100% money-back guarantee, but it only covers being found ineligible during onboarding
Cancellation Policy	Not published	Plans run monthly or in 3+ month blocks; no separate cancellation policy published

Which should you choose?

Choose System Labs if you:

→Want to save $63/month with a more affordable option
→Want more medication options to choose from
→Value: prices are published openly for every product, with the renewal rate shown alongside the introductory one: nad+ $89 first month then $149, sermorelin $109 then $219, glutathione $79 then $149, oral sermorelin $79 then $159, mic + b12 $89/mo and ghk-cu cream $109/mo (checked july 28, 2026)

Get started with System Labs

Choose Enhance MD if you:

→Prefer a higher-rated service (7.7/10 vs 6.5/10)
→Value: one price at every dose, stated as 'one consistent price from your first dose to your last', so titrating up never raises the bill

Get started with Enhance MD

Website previews

System Labs

System Labs website

Enhance MD

Enhance MD website

Our recommendation

Enhance MD comes out ahead with a higher rating of 7.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Enhance MD

Related comparisons

System Labs vs CoreAge Rx

System Labs vs Zepbound

System Labs vs Mounjaro

System Labs vs Wegovy Pill

System Labs vs Foundayo

System Labs vs Wegovy

System Labs vs NovoCare Pharmacy

System Labs vs Ozempic

System Labs vs Form Health

System Labs vs Henry Meds

System Labs vs Sesame Care

System Labs vs FuturHealth

System Labs vs Circle Medical

System Labs vs Ro

System Labs vs Midi Health

System Labs vs Noom Med

System Labs vs Precision Telemed

System Labs vs Hims

System Labs vs Calibrate

System Labs vs PlushCare

Compare other providers

Compare GLP-1 Brands

First Brand

vs

Second Brand