TMates vs Amie
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
TMates vs Amie: Overview
Choosing between TMates and Amie for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
TMates offers both semaglutide and tirzepatide at $249/month with a rating of 7.8/10. Amie also provides both semaglutide and tirzepatide at $99/month with a 6.5/10 rating.
The price difference of $150/month is significant - Amie is the more budget-friendly option, while TMates positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$150/mo
Rating Difference
1.3
Winner
TMates
Best For
Quality
TMates
View full TMates review →Rating
7.8/10Better
Monthly Price
$249
Medications
semaglutidetirzepatide
Pros
- ✓Both price ladders are published in full and the arithmetic is correct at every tier. Semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked July 27, 2026
- ✓Tirzepatide is laid out the same way: $297 monthly, $267/mo over three ($800), $217/mo over six ($1,299) and $167/mo over twelve ($1,999)
- ✓Every advertised saving checks out - the 13%, 30%, 37%, 10%, 27% and 44% figures all match the underlying numbers
- ✓One price across all doses, from 0.25mg to 2.4mg semaglutide and 2.5mg to 15mg tirzepatide, so titrating up never costs more
- ✓Possible side effects are listed openly on the product page - nausea, injection site reactions, decreased appetite and gastrointestinal discomfort - with a note that most are mild and temporary
- ✓Both injectable and oral formats are offered at the same published prices
- ✓Medication, provider review, personalised dosing and ongoing support are all included in the price, with free shipping and cancel-anytime terms
Cons
- ✗We could not find an explicit statement that the compounded medications are not FDA-approved. The site explains what compounding is but omits the disclosure nearly every competitor makes
- ✗Trustpilot has exactly one review of this domain, so there is effectively no independent evidence about the service against a claim of 2,400+ patients
- ✗Tirzepatide is billed as the 'Most powerful GLP-1 medication available' - a superiority claim made about a compounded preparation that has not been trialled against anything
- ✗The 'up to 15% of their body weight in a year' figure is presented as what TMates has seen in its own patients, with no published data behind it
- ✗The lowest advertised rates require paying for a full year upfront - $1,900 for semaglutide or $1,999 for tirzepatide
- ✗The site is behind bot protection and will not load without JavaScript, so pricing is invisible to anyone browsing with scripts disabled
- ✗No published customer phone number, support email or support hours
- ✗No BBB profile or complaint record to check
Amie
View full Amie review →Rating
6.5/10
Monthly Price
$99Cheaper
Medications
semaglutidetirzepatide
Pros
- ✓Pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
- ✓No shipment unless a provider approves you, stated on the pricing panel
- ✓Optional add-ons are priced separately and openly rather than bundled in silently
Cons
- ✗The FDA has formally told Amie that its website misrepresented its compounded products - see the warning letter above
- ✗The medication is compounded and therefore not FDA-approved - the agency has not reviewed it for safety, effectiveness or manufacturing quality
- ✗Compounded GLP-1 pricing in this tier is cheap partly because the product carries none of the trial programme, patent or distribution costs of the approved drug - and none of its regulatory review either
- ✗The three-month rate requires paying $249 up front
- ✗No phone number or support hours published
Feature-by-feature comparison
| Feature | TMates | Amie |
|---|---|---|
| Monthly Price | $249 | $99 |
| Rating | 7.8/10 | 6.5/10 |
| Medications | semaglutide, tirzepatide | semaglutide, tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | Not published | Not published |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free shipping; timeframe not published | Not published; no shipment unless approved |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Ongoing provider support included | Not published |
| Money-back Guarantee | None published | None published |
| Cancellation Policy | Cancel anytime, but multi-month plans are paid upfront | Monthly or 3-month plans; terms not summarised on the pricing panel |
Which should you choose?
Choose TMates if you:
- →Prefer a higher-rated service (7.8/10 vs 6.5/10)
- →Value: both price ladders are published in full and the arithmetic is correct at every tier. semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked july 27, 2026
Choose Amie if you:
- →Want to save $150/month with a more affordable option
- →Value: pricing is published before signup: $99/month on the monthly plan, or $83/month on a 3-month plan billed at $249
Website previews
TMates
Amie
Our recommendation
TMates comes out ahead with a higher rating of 7.8/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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