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TMates vs SynergyRX

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

TMates vs SynergyRX: Overview

Choosing between TMates and SynergyRX for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

TMates offers both semaglutide and tirzepatide at $249/month with a rating of 7.8/10. SynergyRX also provides both semaglutide and tirzepatide at $199/month with a 7.4/10 rating.

With only a $50/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$50/mo

Rating Difference

0.4

Winner

TMates

Best For

Quality

TMates

View full TMates review →

Rating

7.8/10Better

Monthly Price

$249

Medications

semaglutidetirzepatide

Pros

✓Both price ladders are published in full and the arithmetic is correct at every tier. Semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked July 27, 2026
✓Tirzepatide is laid out the same way: $297 monthly, $267/mo over three ($800), $217/mo over six ($1,299) and $167/mo over twelve ($1,999)
✓Every advertised saving checks out - the 13%, 30%, 37%, 10%, 27% and 44% figures all match the underlying numbers
✓One price across all doses, from 0.25mg to 2.4mg semaglutide and 2.5mg to 15mg tirzepatide, so titrating up never costs more
✓Possible side effects are listed openly on the product page - nausea, injection site reactions, decreased appetite and gastrointestinal discomfort - with a note that most are mild and temporary
✓Both injectable and oral formats are offered at the same published prices
✓Medication, provider review, personalised dosing and ongoing support are all included in the price, with free shipping and cancel-anytime terms

Cons

✗We could not find an explicit statement that the compounded medications are not FDA-approved. The site explains what compounding is but omits the disclosure nearly every competitor makes
✗Trustpilot has exactly one review of this domain, so there is effectively no independent evidence about the service against a claim of 2,400+ patients
✗Tirzepatide is billed as the 'Most powerful GLP-1 medication available' - a superiority claim made about a compounded preparation that has not been trialled against anything
✗The 'up to 15% of their body weight in a year' figure is presented as what TMates has seen in its own patients, with no published data behind it
✗The lowest advertised rates require paying for a full year upfront - $1,900 for semaglutide or $1,999 for tirzepatide
✗The site is behind bot protection and will not load without JavaScript, so pricing is invisible to anyone browsing with scripts disabled
✗No published customer phone number, support email or support hours
✗No BBB profile or complaint record to check

SynergyRX

View full SynergyRX review →

Rating

7.4/10

Monthly Price

$199Cheaper

Medications

semaglutidetirzepatide

Pros

✓A complete GLP-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked July 27, 2026)
✓Brand-name options are priced too, and Ozempic at $499 is notably cheaper here than Wegovy or Mounjaro at $947
✓Oral dissolving tablet versions of both molecules are available for people who will not inject
✓A $100 welcome credit is applied automatically at checkout with no code to hunt for
✓FSA and HSA eligible, with free shipping
✓The FAQ explicitly raises the compounded-versus-brand-name question rather than avoiding it
✓Longevity, hair, skin and sexual health lines are available from the same provider

Cons

✗On a weight-loss landing page, the product carousel opens on the longevity tab. Every GLP-1 and its price is hidden behind a 'WEIGHT LOSS' tab you have to find and click - a visitor who does not spot it sees only NAD+, sermorelin, glutathione, B12 and PT-141
✗There is no public review footprint at all - no Trustpilot profile, no BBB file - against a claim of 50,000+ patients
✗The oral tablets cost more than the injections ($299 against $199 for semaglutide), the reverse of how most competitors price them, with no explanation given
✗The call-to-action button reads 'SEE IF I'M ELLIGIBLE' - misspelled, and repeated twice on the page
✗The headline - 'The Proven Way to lose 15% of your body weight fast! Lose 1-2lbs per week' - is word-for-word the copy used by TrimRx and Embody, indicating a shared white-label funnel rather than an independently written site
✗The testimonial block under a weight-loss heading mixes weight-loss quotes with an NAD+ energy testimonial, and the same three quotes repeat on a loop
✗No refund or cancellation policy could be found anywhere on the site
✗No published phone number, support email or support hours

Choose SynergyRX

Feature-by-feature comparison

Feature	TMates	SynergyRX
Monthly Price	$249	$199
Rating	7.8/10	7.4/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; timeframe not published	Fast, free shipping claimed
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing provider support included	Not published
Money-back Guarantee	None published	None published
Cancellation Policy	Cancel anytime, but multi-month plans are paid upfront	Not published

Which should you choose?

Choose TMates if you:

→Prefer a higher-rated service (7.8/10 vs 7.4/10)
→Value: both price ladders are published in full and the arithmetic is correct at every tier. semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked july 27, 2026

Get started with TMates

Choose SynergyRX if you:

→Want to save $50/month with a more affordable option
→Value: a complete glp-1 price list is published once you open the weight-loss tab: compounded semaglutide $199, compounded tirzepatide $349, oral dissolving semaglutide $299 and oral tirzepatide $399 (checked july 27, 2026)

Get started with SynergyRX

Website previews

TMates

TMates website

SynergyRX

SynergyRX website

Our recommendation

TMates comes out ahead with a higher rating of 7.8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with TMates

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