TMates vs TRT Nation
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
TMates vs TRT Nation: Overview
Choosing between TMates and TRT Nation for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.
TMates offers both semaglutide and tirzepatide at $249/month with a rating of 7.8/10. TRT Nation offers tirzepatide at $219/month with a 7.5/10 rating.
With only a $30/month price difference, your choice will likely come down to features, support quality, and medication options.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$30/mo
Rating Difference
0.3
Winner
TMates
Best For
Quality
TMates
View full TMates review →Rating
7.8/10Better
Monthly Price
$249
Medications
semaglutidetirzepatide
Pros
- ✓Both price ladders are published in full and the arithmetic is correct at every tier. Semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked July 27, 2026
- ✓Tirzepatide is laid out the same way: $297 monthly, $267/mo over three ($800), $217/mo over six ($1,299) and $167/mo over twelve ($1,999)
- ✓Every advertised saving checks out - the 13%, 30%, 37%, 10%, 27% and 44% figures all match the underlying numbers
- ✓One price across all doses, from 0.25mg to 2.4mg semaglutide and 2.5mg to 15mg tirzepatide, so titrating up never costs more
- ✓Possible side effects are listed openly on the product page - nausea, injection site reactions, decreased appetite and gastrointestinal discomfort - with a note that most are mild and temporary
- ✓Both injectable and oral formats are offered at the same published prices
- ✓Medication, provider review, personalised dosing and ongoing support are all included in the price, with free shipping and cancel-anytime terms
Cons
- ✗We could not find an explicit statement that the compounded medications are not FDA-approved. The site explains what compounding is but omits the disclosure nearly every competitor makes
- ✗Trustpilot has exactly one review of this domain, so there is effectively no independent evidence about the service against a claim of 2,400+ patients
- ✗Tirzepatide is billed as the 'Most powerful GLP-1 medication available' - a superiority claim made about a compounded preparation that has not been trialled against anything
- ✗The 'up to 15% of their body weight in a year' figure is presented as what TMates has seen in its own patients, with no published data behind it
- ✗The lowest advertised rates require paying for a full year upfront - $1,900 for semaglutide or $1,999 for tirzepatide
- ✗The site is behind bot protection and will not load without JavaScript, so pricing is invisible to anyone browsing with scripts disabled
- ✗No published customer phone number, support email or support hours
- ✗No BBB profile or complaint record to check
TRT Nation
View full TRT Nation review →Rating
7.5/10
Monthly Price
$219Cheaper
Medications
tirzepatide
Pros
- ✓Flat pricing that does not punish titration: $219/month for tirzepatide with "Same Price at Any Dose — No Tiered Price Hikes"
- ✓Everything needed to inject is included - syringes, needles and step-by-step instructions - which sounds small until you have to source them yourself
- ✓Free, discreet shipping direct to your door
- ✓A published phone number, 813-413-1000, and stated support hours of Monday to Friday 10am-5pm EST
- ✓Provider-led care with ongoing medical consultations included rather than charged per visit
- ✓Weight-loss claims are footnoted to the actual trial - SURMOUNT-1, 72 weeks - with the caveat that individual results vary and are not guaranteed
- ✓An established men's health clinic with adjacent testosterone, anti-aging and sexual-health services and in-house lab ordering
Cons
- ✗A three-month minimum purchase, so $219/month is really a $657 commitment before you know how you tolerate the medication
- ✗The medication is compounded, not FDA-approved
- ✗Support hours are narrow: Monday to Friday, 10am to 5pm EST only, with nothing at evenings or weekends
- ✗Marketing claims are large and unverifiable from the page: "Trusted by 350,000+ Men" and "4.9★ (2,000+ Reviews)" are presented without linking to the source of either figure
- ✗Tirzepatide only - no semaglutide option within the weight-loss line
- ✗Framed entirely around men, so it is not the right starting point if you are not one
- ✗No insurance billing, and HSA/FSA acceptance is not stated
- ✗The scrolling marquee of claims across the top of the page is closer to advertising than disclosure
Feature-by-feature comparison
| Feature | TMates | TRT Nation |
|---|---|---|
| Monthly Price | $249 | $219 |
| Rating | 7.8/10 | 7.5/10 |
| Medications | semaglutide, tirzepatide | tirzepatide |
| Insurance Accepted | No | No |
| Support Hours | Not published | Monday to Friday, 10am-5pm EST |
| Live Chat | No | No |
| Free Shipping | Yes | Yes |
| Shipping Speed | Free shipping; timeframe not published | Free, discreet shipping direct to your door |
| Mobile App | No | No |
| Dedicated Coach | Not included | Not included |
| Follow-up Frequency | Ongoing provider support included | Ongoing medical consultations and provider check-ins included |
| Money-back Guarantee | None published | None published |
| Cancellation Policy | Cancel anytime, but multi-month plans are paid upfront | Three-month minimum purchase on the tirzepatide programme |
Which should you choose?
Choose TMates if you:
- →Prefer a higher-rated service (7.8/10 vs 7.5/10)
- →Want more medication options to choose from
- →Value: both price ladders are published in full and the arithmetic is correct at every tier. semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked july 27, 2026
Choose TRT Nation if you:
- →Want to save $30/month with a more affordable option
- →Value: flat pricing that does not punish titration: $219/month for tirzepatide with "same price at any dose — no tiered price hikes"
Website previews
TMates
TRT Nation
Our recommendation
TMates comes out ahead with a higher rating of 7.8/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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