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TMates vs Yucca Health

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

TMates vs Yucca Health: Overview

Choosing between TMates and Yucca Health for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

TMates offers both semaglutide and tirzepatide at $249/month with a rating of 7.8/10. Yucca Health also provides both semaglutide and tirzepatide at $146/month with a 8/10 rating.

The price difference of $103/month is significant - Yucca Health is the more budget-friendly option, while TMates positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$103/mo

Rating Difference

0.2

Winner

Yucca Health

Best For

Budget

TMates

View full TMates review →

Rating

7.8/10

Monthly Price

$249

Medications

semaglutidetirzepatide

Pros

✓Both price ladders are published in full and the arithmetic is correct at every tier. Semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked July 27, 2026
✓Tirzepatide is laid out the same way: $297 monthly, $267/mo over three ($800), $217/mo over six ($1,299) and $167/mo over twelve ($1,999)
✓Every advertised saving checks out - the 13%, 30%, 37%, 10%, 27% and 44% figures all match the underlying numbers
✓One price across all doses, from 0.25mg to 2.4mg semaglutide and 2.5mg to 15mg tirzepatide, so titrating up never costs more
✓Possible side effects are listed openly on the product page - nausea, injection site reactions, decreased appetite and gastrointestinal discomfort - with a note that most are mild and temporary
✓Both injectable and oral formats are offered at the same published prices
✓Medication, provider review, personalised dosing and ongoing support are all included in the price, with free shipping and cancel-anytime terms

Cons

✗We could not find an explicit statement that the compounded medications are not FDA-approved. The site explains what compounding is but omits the disclosure nearly every competitor makes
✗Trustpilot has exactly one review of this domain, so there is effectively no independent evidence about the service against a claim of 2,400+ patients
✗Tirzepatide is billed as the 'Most powerful GLP-1 medication available' - a superiority claim made about a compounded preparation that has not been trialled against anything
✗The 'up to 15% of their body weight in a year' figure is presented as what TMates has seen in its own patients, with no published data behind it
✗The lowest advertised rates require paying for a full year upfront - $1,900 for semaglutide or $1,999 for tirzepatide
✗The site is behind bot protection and will not load without JavaScript, so pricing is invisible to anyone browsing with scripts disabled
✗No published customer phone number, support email or support hours
✗No BBB profile or complaint record to check

Yucca Health

View full Yucca Health review →

Rating

8/10Better

Monthly Price

$146Cheaper

Medications

semaglutidetirzepatide

Pros

✓The FAQ publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked July 27, 2026
✓A lifetime price lock is offered under code YUCCA4LIFE at $146/mo, which if honoured protects against the mid-treatment increases common in this category
✓Trustpilot rating of 4.6 across 1,197 reviews, closely matching the figure shown on site
✓The compounded, not-FDA-approved status is spelled out in full, including the point that these drugs do not undergo FDA review for manufacturing quality
✓The whole site is available in Spanish, which almost no other provider in this category offers
✓Licensed providers in all 50 states, US-licensed pharmacies and free expedited shipping
✓Refund policy and shipping policy are both published as separate documents
✓NAD+ and sermorelin are available if you want more than weight care, without being bundled into the GLP-1 price

Cons

✗A developer's note is rendering inside the live page. Between the product cards the text reads: 'the SSR pass triggers an "Invalid hook call" because the React renderer dispatcher is null in the Cloudflare Workers SSR pipeline'. An engineering comment left in production is not reassuring on a site handling prescriptions
✗Secondary product pricing contradicts itself: NAD+ is shown as 'Starting at $158' in one block and 'As low as $215' in another, and sermorelin as both '$158' and '$199'
✗'Pricing is shared after intake once eligibility is confirmed' sits directly above a FAQ answer that then states all the prices, so the site cannot decide whether pricing is gated
✗Social-proof counters disagree with each other - one product card claims '1000+ Patients enrolled in last 7 days' while others on the same page say '100+'
✗Describing compounded products as having 'the same active pharmaceutical ingredients as brand-name drugs' is the claim type the FDA cited in a February 2026 warning letter to a competitor, even though Yucca does disclaim FDA approval immediately afterwards
✗The 'for life' price lock has no published terms explaining what would void it
✗No published phone number or support hours
✗No BBB profile or complaint record to check against the Trustpilot score

Choose Yucca Health

Feature-by-feature comparison

Feature	TMates	Yucca Health
Monthly Price	$249	$146
Rating	7.8/10	8/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Not published	Not published
Live Chat	No	No
Free Shipping	Yes	Yes
Shipping Speed	Free shipping; timeframe not published	Free expedited shipping claimed
Mobile App	No	No
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing provider support included	Not published
Money-back Guarantee	None published	A refund policy is published as a separate document; no blanket money-back guarantee is advertised
Cancellation Policy	Cancel anytime, but multi-month plans are paid upfront	Published separately; the lifetime price lock has no stated conditions

Which should you choose?

Choose TMates if you:

→Value: both price ladders are published in full and the arithmetic is correct at every tier. semaglutide runs $249 for one month, $217/mo over three ($650), $175/mo over six ($1,050) and $158/mo over twelve ($1,900), checked july 27, 2026

Get started with TMates

Choose Yucca Health if you:

→Want to save $103/month with a more affordable option
→Prefer a higher-rated service (8/10 vs 7.8/10)
→Value: the faq publishes actual prices rather than a teaser: semaglutide $146/month and tirzepatide $258/month, with six-month plans at $750 total for semaglutide ($125/mo) and $1,350 for tirzepatide ($225/mo), checked july 27, 2026

Get started with Yucca Health

Website previews

TMates

TMates website

Yucca Health

Yucca Health website

Our recommendation

Yucca Health comes out ahead with a higher rating of 8/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Yucca Health

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