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Trimi Health vs Sesame Care

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

Trimi Health vs Sesame Care: Overview

Choosing between Trimi Health and Sesame Care for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.

Trimi Health offers both semaglutide and tirzepatide at $175/month with a rating of 8.2/10. Sesame Care also provides both semaglutide and tirzepatide at $125/month with a 8.4/10 rating.

With only a $50/month price difference, your choice will likely come down to features, support quality, and medication options.

Our recommended brand

After reviewing all 86 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$50/mo

Rating Difference

0.2

Winner

Sesame Care

Best For

Budget

Trimi Health

View full Trimi Health review →

Rating

8.2/10

Monthly Price

$175

Medications

semaglutidetirzepatide

Pros

✓Publishes a complete price ladder rather than a single teaser figure: compounded semaglutide is $175 billed monthly, $145/mo on quarterly, $120/mo on bi-annual and $99/mo on annual billing ($1,188 upfront), checked July 26, 2026
✓Compounded tirzepatide advertised from $125/mo on annual billing, flat across every dose so titrating up does not raise your bill
✓The refund policy is the clearest we have read in this category: cancel any time before a clinician issues your prescription for a full refund with no fees, and a full refund including the consultation fee if a clinician decides you are not a fit
✓It also explains why the cutoff exists, citing USP <795> and <797> rules on patient-specific compounded sterile preparations rather than just asserting that sales are final
✓A 6-month money-back promise: follow the plan and your provider's guidance for six months and, if you have not lost weight, you can request a refund of the plan fees (terms apply)
✓Clinical care is provided by a named network, Arora Health, and the compounded status is disclosed repeatedly - the medications are 'not FDA-approved as drugs'
✓Free overnight shipping, FSA/HSA eligibility, and Affirm, Klarna and Afterpay financing at checkout
✓Damaged or missing deliveries are handled within 24 hours by replacement, refund or carrier claim

Cons

✗The headline $99/mo requires paying $1,188 up front for a year. Billed monthly the same treatment is $175 - a 77% difference the landing page does not put next to the $99
✗The site markets compounded semaglutide as the 'Same active ingredient as Wegovy' and tirzepatide as 'Same as Mounjaro'. That is the exact claim type the FDA cited in its February 2026 warning letter to another telehealth firm, on the basis that it implies the compounded product has been FDA-approved when it has not
✗Efficacy figures are borrowed from trials of the branded drugs and then applied to compounded copies and to individual readers - 'You could lose 44 lbs per the 22% clinical average'. No compounded product has been through those trials
✗The '22% clinical average' overstates the source: tirzepatide's SURMOUNT-1 trial reported about 20.9% mean weight loss at the top 15 mg dose over 72 weeks
✗The '4.5' rating and '50,233+ patients' shown on the site carry no source, and we could not find a Trustpilot profile for the domain to check either figure
✗Once a clinician issues your prescription the order is final and non-refundable, even if the medication has not shipped
✗Trimi publishes provider ranking articles that place Trimi first - 'Cheapest Tirzepatide Providers 2026: Trimi $125/mo of 10 Ranked' - and a guide titled 'How to Cancel TrimRx & Switch to Trimi'. Treat that content as marketing, not independent research
✗No BBB profile and no public complaint history means there is little independent record to check before you commit to an annual plan

Choose Trimi Health

Sesame Care

View full Sesame Care review →

Rating

8.4/10Better

Monthly Price

$125Cheaper

Medications

semaglutidetirzepatide

Pros

✓Low upfront cost
✓No subscription required
✓Multiple providers
✓Transparent marketplace

Cons

✗Variable pricing
✗Quality varies by provider
✗Less structured program

Choose Sesame Care

Feature-by-feature comparison

Feature	Trimi Health	Sesame Care
Monthly Price	$175	$125
Rating	8.2/10	8.4/10
Medications	semaglutide, tirzepatide	semaglutide, tirzepatide
Insurance Accepted	No	No
Support Hours	Support advertised 24/7 via the patient portal	Mon-Fri 9AM-9PM ET
Live Chat	No	Available
Free Shipping	Yes	No
Shipping Speed	Free overnight shipping claimed	Varies by provider
Mobile App	No	Available
Dedicated Coach	Not included	Not included
Follow-up Frequency	24/7 provider messaging and ongoing check-ins included	Varies by provider
Money-back Guarantee	Full refund before a prescription is issued, plus a 6-month money-back promise if you follow the plan and do not lose weight (terms apply)	Varies by provider
Cancellation Policy	Cancel any time before your prescription is issued for a full refund; once issued, the order is final	No subscription, book as needed

Which should you choose?

Choose Trimi Health if you:

→Value: publishes a complete price ladder rather than a single teaser figure: compounded semaglutide is $175 billed monthly, $145/mo on quarterly, $120/mo on bi-annual and $99/mo on annual billing ($1,188 upfront), checked july 26, 2026

Get started with Trimi Health

Choose Sesame Care if you:

→Want to save $50/month with a more affordable option
→Prefer a higher-rated service (8.4/10 vs 8.2/10)
→Value: low upfront cost

Get started with Sesame Care

Website previews

Trimi Health

Trimi Health website

Sesame Care

Sesame Care website

Our recommendation

Sesame Care comes out ahead with a higher rating of 8.4/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with Sesame Care

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