Trimi Health vs Sesame Care
Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey
Trimi Health vs Sesame Care: Overview
Choosing between Trimi Health and Sesame Care for GLP-1 weight loss medication? Both are highly-rated providers, but they differ in pricing, medication options, and service features.
Trimi Health offers both semaglutide and tirzepatide at $175/month with a rating of 8.2/10. Sesame Care also provides both semaglutide and tirzepatide at $59/month with a 8.7/10 rating.
The price difference of $116/month is significant - Sesame Care is the more budget-friendly option, while Trimi Health positions itself as a premium service.
Our recommended brand
After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.
At a glance
Price Difference
$116/mo
Rating Difference
0.5
Winner
Sesame Care
Best For
Budget
Trimi Health
View full Trimi Health review →Rating
8.2/10
Monthly Price
$175
Medications
semaglutidetirzepatide
Pros
- ✓Publishes a complete price ladder rather than a single teaser figure: compounded semaglutide is $175 billed monthly, $145/mo on quarterly, $120/mo on bi-annual and $99/mo on annual billing ($1,188 upfront), checked July 26, 2026
- ✓Compounded tirzepatide advertised from $125/mo on annual billing, flat across every dose so titrating up does not raise your bill
- ✓The refund policy is the clearest we have read in this category: cancel any time before a clinician issues your prescription for a full refund with no fees, and a full refund including the consultation fee if a clinician decides you are not a fit
- ✓It also explains why the cutoff exists, citing USP <795> and <797> rules on patient-specific compounded sterile preparations rather than just asserting that sales are final
- ✓A 6-month money-back promise: follow the plan and your provider's guidance for six months and, if you have not lost weight, you can request a refund of the plan fees (terms apply)
- ✓Clinical care is provided by a named network, Arora Health, and the compounded status is disclosed repeatedly - the medications are 'not FDA-approved as drugs'
- ✓Free overnight shipping, FSA/HSA eligibility, and Affirm, Klarna and Afterpay financing at checkout
- ✓Damaged or missing deliveries are handled within 24 hours by replacement, refund or carrier claim
Cons
- ✗The headline $99/mo requires paying $1,188 up front for a year. Billed monthly the same treatment is $175 - a 77% difference the landing page does not put next to the $99
- ✗The site markets compounded semaglutide as the 'Same active ingredient as Wegovy' and tirzepatide as 'Same as Mounjaro'. That is the exact claim type the FDA cited in its February 2026 warning letter to another telehealth firm, on the basis that it implies the compounded product has been FDA-approved when it has not
- ✗Efficacy figures are borrowed from trials of the branded drugs and then applied to compounded copies and to individual readers - 'You could lose 44 lbs per the 22% clinical average'. No compounded product has been through those trials
- ✗The '22% clinical average' overstates the source: tirzepatide's SURMOUNT-1 trial reported about 20.9% mean weight loss at the top 15 mg dose over 72 weeks
- ✗The '4.5' rating and '50,233+ patients' shown on the site carry no source, and we could not find a Trustpilot profile for the domain to check either figure
- ✗Once a clinician issues your prescription the order is final and non-refundable, even if the medication has not shipped
- ✗Trimi publishes provider ranking articles that place Trimi first - 'Cheapest Tirzepatide Providers 2026: Trimi $125/mo of 10 Ranked' - and a guide titled 'How to Cancel TrimRx & Switch to Trimi'. Treat that content as marketing, not independent research
- ✗No BBB profile and no public complaint history means there is little independent record to check before you commit to an annual plan
Sesame Care
View full Sesame Care review →Rating
8.7/10Better
Monthly Price
$59Cheaper
Medications
semaglutidetirzepatideorforglipron
Pros
- ✓Publishes cash prices dose by dose, which no other provider on this site does. Zepbound KwikPen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
- ✓The same detail applies across the range: Wegovy pill $149/mo (1.5mg, 4mg) or $299 (9mg, 25mg); Wegovy pen $199 for the first two months for new patients then $349; Foundayo from $149 to $349 depending on dose (checked July 27, 2026)
- ✓Every medication offered is FDA-approved and branded - no compounded product is involved
- ✓Insurance is accepted, and with coverage medication can drop to as low as $25/mo
- ✓The care programme itself - video visits, dedicated provider, labs and messaging - starts at $59/mo
- ✓Efficacy milestones are properly sourced, citing a study of injectable semaglutide 2.4mg with the population spelled out (BMI 30+, or 27+ with a weight-related condition, non-diabetic) and paired with lifestyle change
- ✓A full refund is available if you cancel at least three hours before your first visit
- ✓The wider marketplace lets you compare individual providers on price, with appointments from $37
Cons
- ✗The $59/mo headline depends on a 12-month 'Success by Sesame' commitment, and the annual fee is explicitly non-refundable once paid - cancel in month two and you do not get the remaining ten months back
- ✗Medication costs are not included in the programme price, which Sesame states plainly but which means the real monthly outlay is the subscription plus the drug
- ✗Cash prices escalate steeply with dose. Zepbound more than doubles from $299 to $698 as you titrate to a maintenance dose, so the entry price is not the price you will end up paying
- ✗The Wegovy pen intro rate of $199 applies to new patients only and for two months, after which it is $349
- ✗Monthly subscribers are not refunded for months already paid, even if unused
- ✗Because pricing depends on insurance status, pharmacy and dose, there is no single figure you can plan around before signing up
- ✗This is a general healthcare marketplace, so the weight-loss programme sits alongside urgent care and prescription refills rather than being a dedicated speciality service
Feature-by-feature comparison
| Feature | Trimi Health | Sesame Care |
|---|---|---|
| Monthly Price | $175 | $59 |
| Rating | 8.2/10 | 8.7/10 |
| Medications | semaglutide, tirzepatide | semaglutide, tirzepatide, orforglipron |
| Insurance Accepted | No | Yes |
| Support Hours | Support advertised 24/7 via the patient portal | Not published |
| Live Chat | No | No |
| Free Shipping | Yes | No |
| Shipping Speed | Free overnight shipping claimed | Filled at your pharmacy; not shipped by Sesame |
| Mobile App | No | Available |
| Dedicated Coach | Not included | Included |
| Follow-up Frequency | 24/7 provider messaging and ongoing check-ins included | Ongoing video visits, labs and messaging with a dedicated provider |
| Money-back Guarantee | Full refund before a prescription is issued, plus a 6-month money-back promise if you follow the plan and do not lose weight (terms apply) | Full refund if you cancel at least 3 hours before your first visit; annual fees are non-refundable once paid |
| Cancellation Policy | Cancel any time before your prescription is issued for a full refund; once issued, the order is final | Self-cancel monthly or annual subscriptions any time, but past months and annual fees are not refunded |
Which should you choose?
Choose Trimi Health if you:
- →Value: publishes a complete price ladder rather than a single teaser figure: compounded semaglutide is $175 billed monthly, $145/mo on quarterly, $120/mo on bi-annual and $99/mo on annual billing ($1,188 upfront), checked july 26, 2026
Choose Sesame Care if you:
- →Want to save $116/month with a more affordable option
- →Prefer a higher-rated service (8.7/10 vs 8.2/10)
- →Want more medication options to choose from
- →Need insurance coverage for your treatment
- →Want personalized coaching support included
- →Value: publishes cash prices dose by dose, which no other provider on this site does. zepbound kwikpen is $299/mo at 2.5mg, $398 at 5mg, $499 at 7.5mg and $698 at 10-15mg, so you can see exactly what titrating up will cost before you start
Website previews
Trimi Health
Sesame Care
Our recommendation
Sesame Care comes out ahead with a higher rating of 8.7/10. It also provides multiple medication options including both semaglutide and tirzepatide.
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