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TRT Nation vs PlushCare

Compare pricing, features, and medications to find the best GLP-1 provider for your weight loss journey

TRT Nation vs PlushCare: Overview

Choosing between TRT Nation and PlushCare for GLP-1 weight loss medication? Both are popular providers, but they differ in pricing, medication options, and service features.

TRT Nation focuses on tirzepatide at $219/month with a rating of 7.5/10. PlushCare also provides both semaglutide and tirzepatide at $20/month with a 8.5/10 rating.

The price difference of $199/month is significant - PlushCare is the more budget-friendly option, while TRT Nation positions itself as a premium service.

Our recommended brand

After reviewing all 148 providers on this platform, we've identified CoreAge Rx as offering the most transparent pricing model. At just $99/month — the same price every month, every dose — there are no surprise charges or hidden fees. Combined with exceptional service quality, personalized support, and access to both semaglutide and tirzepatide, it represents the best value without compromising on care.

Visit CoreAge Rx →Read full review

At a glance

Price Difference

$199/mo

Rating Difference

1.0

Winner

PlushCare

Best For

Budget

TRT Nation

View full TRT Nation review →

Rating

7.5/10

Monthly Price

$219

Medications

tirzepatide

Pros

✓Flat pricing that does not punish titration: $219/month for tirzepatide with "Same Price at Any Dose — No Tiered Price Hikes"
✓Everything needed to inject is included - syringes, needles and step-by-step instructions - which sounds small until you have to source them yourself
✓Free, discreet shipping direct to your door
✓A published phone number, 813-413-1000, and stated support hours of Monday to Friday 10am-5pm EST
✓Provider-led care with ongoing medical consultations included rather than charged per visit
✓Weight-loss claims are footnoted to the actual trial - SURMOUNT-1, 72 weeks - with the caveat that individual results vary and are not guaranteed
✓An established men's health clinic with adjacent testosterone, anti-aging and sexual-health services and in-house lab ordering

Cons

✗A three-month minimum purchase, so $219/month is really a $657 commitment before you know how you tolerate the medication
✗The medication is compounded, not FDA-approved
✗Support hours are narrow: Monday to Friday, 10am to 5pm EST only, with nothing at evenings or weekends
✗Marketing claims are large and unverifiable from the page: "Trusted by 350,000+ Men" and "4.9★ (2,000+ Reviews)" are presented without linking to the source of either figure
✗Tirzepatide only - no semaglutide option within the weight-loss line
✗Framed entirely around men, so it is not the right starting point if you are not one
✗No insurance billing, and HSA/FSA acceptance is not stated
✗The scrolling marquee of claims across the top of the page is closer to advertising than disclosure

Choose TRT Nation

PlushCare

View full PlushCare review →

Rating

8.5/10Better

Monthly Price

$20Cheaper

Medications

semaglutidetirzepatideliraglutide

Pros

✓Accepts insurance, which almost nothing else on this site does. Most in-network patients pay a copay of $30 or less for a visit
✓Membership is $19.99/month with the first month free, and there is no minimum commitment
✓Prescribes only FDA-approved medications - Zepbound, Wegovy, Saxenda, Contrave and Xenical - so no compounded product is involved
✓Care comes from board-certified primary care physicians rather than an asynchronous questionnaire review
✓A full refund is offered if the doctor is unable to treat you
✓Membership includes far more than weight care: 24/7 urgent care video visits, mental health support, discounted lab tests and free memberships for family
✓An in-app prescription discount card and HSA/FSA eligibility can reduce medication costs further
✓The site is candid that GLP-1s 'usually cost about $1000 per month out of pocket' and advises checking insurance coverage first, rather than hiding the real figure

Cons

✗The $19.99 membership buys access, not medication. Without insurance coverage the GLP-1 itself can run about $1,000 a month, which PlushCare states openly but which makes the headline price misleading if read as a treatment cost
✗Visits are charged on top of membership - $129 for an initial visit without in-network insurance
✗Trustpilot sits at 3.4 out of 5 across 2,735 reviews, the weakest score of any established provider we have reviewed here
✗Prescriptions are explicitly at the doctor's discretion, so paying for membership and a visit does not guarantee you leave with a GLP-1
✗This is a general telehealth service, so the weight-loss programme has less dedicated structure - no built-in coaching, food tracking or dose-titration support
✗Medication and lab costs are excluded from every advertised price, so your real monthly outlay depends entirely on your insurer
✗Contrave is offered as a $99 cash-pay alternative, but the cash cost of the GLP-1s themselves is not published
✗If you have no insurance and want a GLP-1, this route is likely to cost far more than the compounded providers listed elsewhere on this site

Choose PlushCare

Feature-by-feature comparison

Feature	TRT Nation	PlushCare
Monthly Price	$219	$20
Rating	7.5/10	8.5/10
Medications	tirzepatide	semaglutide, tirzepatide, liraglutide
Insurance Accepted	No	Yes
Support Hours	Monday to Friday, 10am-5pm EST	Video visits available 24/7
Live Chat	No	No
Free Shipping	Yes	No
Shipping Speed	Free, discreet shipping direct to your door	Filled at your pharmacy; not shipped by PlushCare
Mobile App	No	Available
Dedicated Coach	Not included	Not included
Follow-up Frequency	Ongoing medical consultations and provider check-ins included	Ongoing management with a board-certified primary care physician
Money-back Guarantee	None published	Full refund if the doctor is unable to treat you; medication and lab costs are never included
Cancellation Policy	Three-month minimum purchase on the tirzepatide programme	Cancel anytime, no minimum commitment; first month of membership is free

Which should you choose?

Choose TRT Nation if you:

→Value: flat pricing that does not punish titration: $219/month for tirzepatide with "same price at any dose — no tiered price hikes"

Get started with TRT Nation

Choose PlushCare if you:

→Want to save $199/month with a more affordable option
→Prefer a higher-rated service (8.5/10 vs 7.5/10)
→Want more medication options to choose from
→Need insurance coverage for your treatment
→Value: accepts insurance, which almost nothing else on this site does. most in-network patients pay a copay of $30 or less for a visit

Get started with PlushCare

Website previews

TRT Nation

TRT Nation website

PlushCare

PlushCare website

Our recommendation

PlushCare comes out ahead with a higher rating of 8.5/10. It also provides multiple medication options including both semaglutide and tirzepatide.

Get started with PlushCare

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